Background and Objectives: Early-type drug hypersensitivity reactions (DHRs) are observed within the first 1–6 h most commonly manifest as urticaria and/or angioedema. Detailed anamnesis, skin prick tests (SPTs), intradermal (IDTs), oral/intramuscular/intravenous provocation (DPTs) can be used to identify responsible. We aimed evaluate demographic characteristics, responsible drugs, DHR types, DPT results in diagnosis of allergy patients who presented our clinic with suspected allergies....

Data on adult food allergies (FAs) remain limited compared to the pediatric population, and this study investigates prevalence clinical characteristics of FAs among adults. This retrospective included adults aged 18-80 diagnosed with at Immunology Allergy Diseases Clinic Ankara Bilkent City Hospital, Turkey, between 2019 2024. During period, 10,505 patients were examined diagnose manage various allergic immunologic conditions. Among these, 563 suspected having FAs, which was confirmed in 33...

Data showing effectiveness of mepolizumab in patients with eosinophilic granulomatosis polyangiitis (EGPA) are limited.This is a single-center retrospective chart review EGPA treated mepolizumab. Clinical, laboratory, functional parameters and asthma, rhinitis control, quality life scores (Asthma Control Test [ACT], Asthma Quality Life Questionnaire [AQLQ], Rhinoconjunctivitis [RQLQ], SinoNasal Outcome [SNOT]-22) were evaluated at the baseline, 6th month, 12th month. Complete response was...

To explore in elderly patients with rheumatoid arthritis (RA) and comorbidity (1) which order why prioritize their morbidities regard to functioning health, (2) beliefs about common (age-related) musculoskeletal complaints, (3) experiences the influence of on medication treatment RA. Patients between 50 85 years RA ≥ 1 or lifestyle risk factor were invited for a semi-structured interview. Two readers coded transcripts interviews, by using NVivo11 software. Fifteen (14 women; mean age 67...

OBJECTIVES: Management of chronic obstructive pulmonary disease (COPD) includes interventions such as improving skills in coping with the disease.We aimed to examine effect self-management training on quality life and functional parameters patients moderate severe COPD. MATERIALS AND METHODS:Sixty-one consecutive COPD were recruited study prospectively.The randomized into two groups: (n=31) standard care (n=30).Each patient was evaluated by spirometry, assessment test (CAT), St George's...

This year, pollen season coincided with the first wave of coronavirus disease 2019 pandemic. Strict preventive measures have been implemented during April and May then a normalization phase started in our country June. Our aim is to evaluate effect pandemic process on allergic airway symptoms.A prospective questionnaire-based study was planned questionnaire form sent cell-phones subjects allergy followed clinic. Number airborne grass pollens determined by Burkard volumetric 7-day spore...

Mepolizumab has been approved as a treatment option for severe eosinophilic asthma (SEA) patients in our country. We aimed to evaluate the clinical and functional efficacy of mepolizumab this group real life well response rates possible factors affecting response.The study was retrospective chart review with SEA treated mepolizumab. The data were collected at baseline, 6th 12th month.A total 62 (41F/21M) mean age 44.41 ± 13.24 years included study. They had poor symptom control test (ACT)...

CoronaVac, the first coronavirus disease 2019 vaccine administered in our country, was found safe clinical trials.We aimed to reveal rate and features of CoronaVac vaccine-associated allergic reactions among vaccinated healthcare workers (HCWs) real-life.This study planned as a questionnaire-based study. Participants who reported postvaccination reaction were interviewed on phone their medical records also checked for confirmation.A total 2,488 HCWs took part 4,054 complete...

Allergen-specific immunotherapy (AIT) is accepted as the only disease-modifying therapy for IgE-mediated allergic airway diseases and hymenoptera venom allergy. AIT requires repeated contact between patient physician or nurse in hospital. Because it a long-term treatment, compliance essential issue to obtain maximal efficacy. Coronavirus disease 2019 (COVID-19) pandemic reshaped doctor-patient interaction pattern of hospital admissions.We aimed determine possible changes administration...

Studies have shown the frequency of anxiety and depression decreased quality life (QoL) in patients with allergic diseases. The aim this study was to evaluate symptoms QoL asthma, rhinitis (AR), urticaria/angioedema (U/A) drug allergy without any psychiatric diagnosis compare these four diseases respects. In cross-sectional demographic clinical characteristics were collected from patients’records. Hospital Anxiety Depression Scale (HADS) Short Form 36 (SF-36) used assess QoL. A total 159...

Introduction: We aimed to investigate the frequency and sociodemographic clinical distinguishing features of asthmatic patients in whom long-acting muscarinic antagonists (LAMA) were added maintenance therapy our clinic. Methods: In this cross-sectional study, data on sociodemographic, phenotypic, characteristics with asthma using Steps 4 5 medications, who followed up center for at least 1 year, obtained from file records. Whether received add-on LAMA 6 months was also noted. Results: A...

Background. Asthma is a disease that combines different biological mechanisms, inflammatory pathways, and phenotypic features. Our aim was to investigate the demographic characteristics of patients with asthma reveal distribution phenotypes according endotype groups. Methods. Patients were identified as eosinophilic if absolute eosinophil count measured at least once ≥ 300/μL during oral corticosteroid free period or 150/μL under corticosteroids. sensitive one inhalant allergen skin prick...

According to recent guidelines; patients with controlled asthma who are stable for at least three months and don't have risk factor should be considered step down.To evaluate our down attempts affecting factors.This study was a retrospective-cohort of were followed up in clinic one year. Sociodemographic, phenotypic, clinical features number step-down recorded from the files. Step tried well as successful whether descending maintained or lower reached until last visit.A total 239 (196 F/43...

<b>Introduction:</b> Bacterial colonization is one of the factors determining morbidity in bronchiectasis. <b>Methods:</b> Data 100 stable bronchiectasis patients who were under follow up with sputum cultures evaluated. <b>Results:</b> Patients had a mean age 55(60M,40F). Overall 38 or more bacterial growth cultures. Nineteen patients(36%) <i>H.influenza</i>, 17(32%) <i>P.aeurginosa</i>, 7(13%) <i>S.pneumonia</i>, 6(11%) <i>M.catarhallis</i>, 2(4%) <i>S.aureus</i> and <i>E.coli</i>. FEV1...

The profile of severe asthmatics: Results from a specialized asthma clinic Introduction: In patients with asthma, individualized treatment, and appropriate phenotyping are required to achieve control.In our study, aim was examine the characteristics specific patient group in tertiary outpatient clinic, which is primary setting for evaluating patients, intention obtaining national data. Materials Methods:In this cross-sectional observational sociodemographic, clinical presentations,...

Randomized controlled studies have shown that anti-IL-5 treatments reduce the need for oral corticosteroids, annual asthma exacerbation and hospitalization rates, blood eosinophil count increase FEV1 values, control, quality of life in patients with eosinophilic severe asthma. Although number real-life is limited, there are 10 real mepolizumab, one study benralizumab reslizumab current literature. Similar to randomized trials, reported a reduction counts control test scores, Response...

Tumor necrosis factor-alpha (TNF-α) inhibitors are effective alternatives for chronic inflammatory diseases.They generally well tolerated; however, they may lead to the immediate/delayed local or systemic hypersensitivity reactions (HSR).Tocilizumab is a monoclonal antibody against interleukin 6 receptors.It given both via intravenous (IV) and subcutaneous (SC) routes there limited data reporting that overall injection and/or infusion reaction rate tocilizumab estimated as...