- Lymphoma Diagnosis and Treatment
- Nanoparticle-Based Drug Delivery
- COVID-19 Clinical Research Studies
- RNA Interference and Gene Delivery
- CRISPR and Genetic Engineering
- Long-Term Effects of COVID-19
- Advanced biosensing and bioanalysis techniques
- SARS-CoV-2 and COVID-19 Research
- Antifungal resistance and susceptibility
- Saffron Plant Research Studies
- Chemotherapy-related skin toxicity
- Chronic Lymphocytic Leukemia Research
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Fungal Infections and Studies
- Peptidase Inhibition and Analysis
- Inflammatory Biomarkers in Disease Prognosis
- Graphene and Nanomaterials Applications
- Retinoids in leukemia and cellular processes
- Synthesis and biological activity
- Animal Disease Management and Epidemiology
- Nanoplatforms for cancer theranostics
- Monoclonal and Polyclonal Antibodies Research
- Vector-Borne Animal Diseases
- Plant chemical constituents analysis
Shahid Sadoughi University of Medical Sciences and Health Services
2024-2025
Mashhad University of Medical Sciences
2015-2024
Ghaem Hospital
2016-2024
University of Pittsburgh
2024
Tabriz University of Medical Sciences
2022-2023
Zanjan University of Medical Sciences
2020-2022
Biotechnology Research Center
2021-2022
Aim: To prepare a novel hybrid system for the controlled release and delivery of curcumin (CUR). Methods: A method ultrasound-assisted fabrication protein-modified nanosized graphene oxide-like carbon-based nanoparticles (CBNPs) was developed. After being modified with bovine serum albumin (BSA), CUR loaded onto synthesized (labeled CBNPs@BSA-CUR). The structure properties were elucidated using transmission electron microscopy (TEM), atomic force (AFM), ultraviolet-visible spectroscopy...
Crocetin, the major carotenoid in saffron, exhibits potent anticancer effects. However, antileukemic effects of crocetin are still unclear, especially primary acute promyelocytic leukemia (APL) cells. In current study, potential antipromyelocytic activity and underlying molecular mechanisms were investigated. Crocetin (100 µM), like standard anti-APL drugs, all-trans retinoic acid (ATRA, 10 µM) As2 O 3 (arsenic trioxide, 50 significantly inhibited proliferation induced apoptosis APL cells,...
Introduction. Breast cancer has been represented a challenging issue worldwide as it is one of the major leading causes death among women. CD81 gene, member tetraspanin protein family, associated with development human cancers. Genome editing technologies, particularly CRISPR-Cas9 system, have shown rapid progress in gene function studies. In this study, we aimed to evaluate ability plasmid-based system modify specific regions MDA-MB-231 breast cell line. Materials and methods. Using...
Introduction: Human coronavirus disease 2019 (COVID-19) is an emerging respiratory that has become pandemic worldwide. The patients have a range of mild to severe symptoms, such as pneumonia, acute distress syndrome, arrhythmia, shock, and other organs involvement. Clinical hematological evidence can serve prognostic factor detect cases COVID-19. Objectives: present study aimed evaluate parameters related the severity in COVID-19 Mashhad, Eastern Iran. Patients Methods: All individuals with...
Aim: Quorum sensing (QS) is a density-dependent chemical process of cell-to-cell communication in which certain signals are activated, leading to the coordination pathogenic behaviors and regulation virulence bacteria. Inhibition QS can prevent biofilm formation reduce Herein, bovine serum albumin (BSA)-coated silver nanoparticles (NPs) (Ag-Ag2S@BSA NPs) were synthesized studied as an anti-QS agent. Materials & methods: Ag-Ag2S NPs prepared through BSA-mediated biomineralization under...
بهمنظور بررسی و مقایسه روشهای شیمیایی غیر مدیریت علفهای هرز مزارع زعفران(Crucus sativus) آزمایشهای مزرعهای طی سالهای 1388 تا 1390 در ایستگاه تحقیقات زعفران گیاهان دارویی شهرستان گناباد بهصورت طرح پایه بلوکهای کامل تصادفی با 6 تیمار سه تکرار به اجرا درآمد. تیمارها شامل گیاه پوششی جو (Hordeum vulgare)، مالچ بستر قارچ، علفکش گالانت سوپر (هالوکسی فوپ-آر- متیل) (EC%10)، علفکش شوالیه (مزوسولفوروم + یدوسولفوروم) (WG%6)، وجین دستی شاهد (عدم کنترل) بودند. تعیین قابلیت کنترل وزن خشک نیز...