A5062698391- Parvovirus B19 Infection Studies
- Cytomegalovirus and herpesvirus research
- HIV/AIDS Research and Interventions
- Prenatal Screening and Diagnostics
- COVID-19 Impact on Reproduction
- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Herpesvirus Infections and Treatments
- COVID-19 and healthcare impacts
- Fetal and Pediatric Neurological Disorders
- Pediatric Urology and Nephrology Studies
- HIV-related health complications and treatments
- Urological Disorders and Treatments
- Neonatal and fetal brain pathology
- Gestational Diabetes Research and Management
- Autopsy Techniques and Outcomes
- Dermatological and COVID-19 studies
- Maternal and Perinatal Health Interventions
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and fetal healthcare
- HIV/AIDS drug development and treatment
- Congenital Heart Disease Studies
- Gestational Trophoblastic Disease Studies
- Virology and Viral Diseases
- Skin and Cellular Biology Research
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2016-2025
University of Milan
1993-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2021
Weatherford College
2021
Agostino Gemelli University Polyclinic
2021
Ospedale Maggiore
2011-2016
Ospedale dei Bambini Vittore Buzzi
2007-2010
To assess the diagnostic and prognostic value of fetal cerebral magnetic resonance (MR) imaging congenital cytomegalovirus (CMV) infection in comparison with that level II ultrasonography (US).Institutional review board approval informed consent for MR data collection were obtained. Thirty-eight fetuses CMV infection, examined by using serial US, underwent (mean gestational age, 25 weeks; age range at first examination, 20-34 weeks). The frequency pathologic findings US (29 cases...
Please cite this paper as: Fabbri E, Revello M, Furione Zavattoni Lilleri D, Tassis B, Quarenghi A, Rustico Nicolini U, Ferrazzi Gerna G. Prognostic markers of symptomatic congenital human cytomegalovirus infection in fetal blood. BJOG 2011;118:448–456. Objective To identify cord blood prognostic (HCMV). Design Retrospective observational study. Setting Fetal medicine unit Milan and Medical virology Pavia, Italy. Population HCMV-infected -uninfected fetuses mothers with primary HCMV during...
To assess whether sonographic diagnosis of fetal head position before instrumental vaginal delivery can reduce the risk failed vacuum extraction and improve outcome.Randomised Italian Sonography for occiput POSition Trial Ante (R.I.S.POS.T.A.) is a randomized controlled trial term (37 + 0 to 41 6 weeks' gestation) singleton pregnancies with cephalic presentation requiring by extraction, which was conducted between April 2014 June 2017 involved 13 maternity hospitals. Patients were assessment...
ABSTRACT A significant increase in Parvovirus B 19 (B19V) infections has been reported the last months some European countries. This outbreak could be highly detrimental for pregnant women, considering capacity of virus to harm fetus. However, magnitude and spread this is yet unclear. Evidence from other areas required there need focus more on impact pregnancy. To aim, women with B19V infection who were managed a referral hospital located Milan, Northern Italy reviewed. The primary aim was...
Chagas Disease (CD), caused by Trypanosoma cruzi, is endemic in Latin America (LA). However, due to migration, it now present globally. We aimed evaluate the prevalence of CD among LA pregnant women Milan, Italy, and incidence T. cruzi transmission their newborns. A prospective multicenter observational study was conducted five different Obstetrics Gynecology outpatient clinics Italy between September 2019 October 2024. Pregnant from areas for were tested means two serological tests directed...
To investigate whether invasive procedures performed in the presence of human cytomegalovirus (HCMV) DNA maternal peripheral blood (HCMV DNAemia) represent a risk for iatrogenic transmission HCMV infection to fetus, 194 pregnant women undergoing prenatal diagnosis because primary and their 199 fetuses were investigated. Overall, 27 (37%) 73 mothers uninfected 22 59 infected DNAemia-positive at amniocentesis. Of 8 with false-negative amniocentesis results, 4 DNAemia-negative Therefore,...
To compare the sonographic measurement of maternal subcutaneous and visceral adipose thickness between pregnant women with gestational diabetes mellitus (GDM) patients nondiabetic pregnancies.Adipose was measured by transabdominal ultrasound in attending our antenatal clinics at 24-28 weeks' gestation. All underwent a 75-g oral glucose challenge as diagnostic test for GDM.The study population comprised 56 positive 112 pregnancies. Measurements tissues were converted into multiples median...
Abstract Background Human cytomegalovirus (HCMV) is the leading infectious cause of congenital disabilities. We designed a prospective study to investigate rate, outcome, and risk factors CMV (cCMV) infection in neonates born immune women, potential need effectiveness hygiene recommendations this population. Methods The was composed 2 sequential parts: an epidemiology (part 1) prevention 2) study. Performance part depended upon cCMV rate >0.4%. Women enrolled 1 did not receive...
Abstract Fifteen fetuses at risk of congenital human cytomegalovirus (HCMV) infection underwent prenatal diagnosis 16–30 weeks' gestation by a combination amniocentesis and fetal blood sampling. HCMV was isolated from the amniotic fluid in six patients, but HCMV‐specific IgM detected only three them. Two nine neonates, who were delivered following negative diagnosis, had diagnosed virus isolation urine. The interval to testing 3 4 weeks two false‐negative cases ⩾ 7 true‐positive cases....
Given the difficulty in establishing exact time of HCMV transmission from mother to fetus, intrauterine infection was investigated 46 infected fetuses/newborns by correlating maternal and fetal parameters with clinical outcome according interval between onset prenatal diagnosis. In detail, 17/28 (60.7%) asymptomatic 18/18 (100%) symptomatic were as a consequence primary acquired ≤8 weeks gestational age, while 11/28 (39.3%) 0/18 (0%) congenitally when >8 weeks' gestation. Symptomatic...
We investigated association between sociodemographic characteristics and COVID-19 disease among pregnant women admitted to our unit, the largest high-risk maternity unit in Milan metropolitan area.Between March 1, 2020 April 30, 2020, 896 were Institution tested for COVID-19. collected information regarding their characteristics. Additional on geographical area of residence, number family members, members positive COVID-19, clinical data was Odds ratios (ORs) 95% confidence intervals (CIs)...
The risk of intrauterine death (IUD) at term varies from less than one to up three cases per 1,000 ongoing pregnancies. cause is often largely undefined. Protocols and criteria prevent define the rates causes stillbirth are subjects important scientific clinical debates. We examined gestational age rate in a 10-year period our maternity hub evaluate possible favorable impact surveillance protocol on maternal fetal well-being growth.Our cohort included all women with singleton pregnancies...
No AccessJournal of UrologyPediatric urology1 Dec 2007Fetal Serum β2-Microglobulin Before and After Bladder Shunting: A 2-Step Approach to Evaluate Fetuses With Lower Urinary Tract Obstruction Frank J. Craparo, Mariangela Rustico, Beatrice Tassis, Dario Coviello, Umberto Nicolini CraparoFrank Craparo , RusticoMariangela Rustico TassisBeatrice Tassis CovielloDario Coviello NicoliniUmberto View All Author Informationhttps://doi.org/10.1016/j.juro.2007.08.052AboutFull TextPDF ToolsAdd...
Three cases of placental chorioangiomas, from 6.5 to 10 cm in diameter, were diagnosed prenatally by ultrasound and color Doppler imaging at 21-34 weeks gestation. In 1 case, due fetal hydrops maternal 'mirror syndrome', immediate delivery a neonate, who was severely anemic, thrombocytopenic had consumption coagulopathy, required. the other 2 pregnancies, conservative management possible, once cardiac failure anemia ruled out combination blood sampling serial echographic investigations.
Fourteen fetuses at risk of Varicella-Zoster virus (VZV) infection underwent prenatal diagnosis 10-24 weeks' gestation by a combination chorionic villus sampling, amniocentesis, and fetal blood sampling. Polymerase chain reaction (PCR) was done on placental tissues, using primers which define 221 bp region the gene coding for 44 kD protein VZV. Positive cases were further analysed dot blot hybridization, radiolabelled DNA probes corresponding to Hind III fragment VZV genome. The rate...
Abstract Objective The technique used to perform transabdominal chorionic villus sampling (CVS) is not standardized, but aspiration of villi generally obtained by discontinuous vacuum created in a syringe, manually or hand‐grip device. We evaluated the feasibility new method performing CVS which employs 4‐mL Vacutainer ® connected needle, producing continuous negative pressure. Methods Two hundred pregnant women, whose gestational age ranged from 10 + 2 16 (mean, 12 1) weeks, entered...