In this paper, we propose the first deep reinforcement learning framework to estimate optimal Dynamic Treatment Regimes from observational medical data. This is more flexible and adaptive for high dimensional action state spaces than existing methods model real life complexity in heterogeneous disease progression treatment choices, with goal provide doctor patients data-driven personalized decision recommendations. The proposed contains a supervised step predict most possible expert actions;...

Identifying drug-drug interactions (DDIs) is a critical enabler for reducing adverse drug events and improving patient safety. Generating proper DDI alerts during prescribing workflow has the potential to prevent DDI-related events. However, implementation of alerting system remains challenge as users are experiencing alert overload which causes fatigue. One strategy optimize current establish list high-priority DDIs purposes, though it resource-intensive task. In this study, we propose...

Patient satisfaction is a key performance indicator of patient-centered care and hospital reimbursement. To discover the major factors that affect patient experiences considered as an effective way to formulate corrective actions. A during his/her healthcare journey interacts with multiple health professionals across different service units. The health-related data generated at each step valuable resource for extracting actionable insights. In particular, self-reported survey associated...

Women's health issues, including menstruation, childbirth, and menopause, significantly impact work performance career progression, pose physical mental burdens on women. Despite their importance, research how these events conditions affect women's quality of life in the workplace is limited. This study explores relationship between living environment, status, factors, working It focuses menstruation-associated symptoms (dysmenorrhea, PMS) menopausal QOL health. A cross-sectional was...

Objectives We compared the care services use and medical institutional deaths among older adults across four home facility types. Design This was a retrospective cohort study. Setting used administrative claims data from April 2014 to March 2017. Participants included 18 347 residents of Fukuoka Prefecture, Japan, who received during period, aged ≥75 years with certified needs at least level 3. were categorised based on (ie, general clinics, Home Care Support Clinics/Hospitals (HCSCs),...

Accurate Traffic Prediction is a challenging task in intelligent transportation due to the spatial-temporal aspects of road networks. The traffic network can be affected by long-distance or long-term dependencies where existing methods fall short modeling them. In this paper, we introduce novel framework known as Spatial-Temporal Multi-Granularity Framework (STMGF) enhance capture and information STMGF makes full use different granularity networks models gathering hierarchical interactive...

In the recent paper \cite{LPY2024SCM}, authors proved existence, uniqueness, regularity and exponential decay property of solution to generalized Leray's problem in a distorted infinite-long pipe with Navier-slip boundary condition, where friction ratio $\alpha>0$ flux $\Phi$ is no bigger than critical $\Phi_0=\frac{C\alpha}{1+\alpha}$. this paper, we consider condition straight $\mathcal{D}=\Sigma\times\mathbb{R}$. We show that if larger value independent $\alpha$, must be Poiseuille flow...

Objective: The current study aimed to identify workplace stress and how factors differed in employees of a multinational company's subsidiaries Japan Vietnam. Methods: For the study, total 340 Japanese 379 Vietnamese workers were included from their corresponding company headquartered Japan. data anonymously collected via an online pre-administered questionnaire between November 2021 February 2022. A brief Job Stress Questionnaire was used assess job stress. Doubly robust estimation combines...

Abstract Objective To explore the relationships between Chinese nurses’ knowledge, perceptions, and attitudes their behavior actual implementation of safety measures when handling antineoplastic drugs (ADs) in daily work. Methods This was a multisite study conducted 8 public hospitals China. A self-administered questionnaire sent to participants querying degree contact with ADs. The hypothesized relations were explored using structural equation modelling via bootstrap method. Mediation...

International immigration into Japan is increasing. It would make sense that investigating the health status of immigrants be associated with improvements in their and beneficial building a complete social security system which minorities can live safely securely. The objective this study to describe explore association between self-rated employment status. As result, half those surveyed had some problem, particularly lot mental stress. We did not find significant relationship status, but it...

Abstract Objectives We compared the care services use and medical institutional deaths among older adults across four home facility types. Design This was a retrospective cohort study. Setting used administrative claims data from April 2014 to March 2017. Participants included 18,347 residents of Fukuoka Prefecture, Japan, who received during period, aged ≥75 years with certified needs at least level 3. were categorized based on (i.e., general clinics, Home Care Support Clinics/Hospitals...

Abstract Background Due to advanced maternal age facing great risks of fertility, such as gestational hypertension, postpartum haemorrhage, miscarriage, etc., we must attach importance care. Guidelines for optimal care are available. It is significance identify potential barriers and tailor practical implementation strategies before implementing the guidelines. The purpose this study aimed use science methods develop that could promote guidelines in clinical practice. Methods Purposive...