A5080864828- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Advanced Radiotherapy Techniques
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Endometrial and Cervical Cancer Treatments
- Intestinal Malrotation and Obstruction Disorders
- Advances in Oncology and Radiotherapy
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Abdominal Trauma and Injuries
- Nonmelanoma Skin Cancer Studies
- Esophageal Cancer Research and Treatment
- Global Cancer Incidence and Screening
- Cancer Diagnosis and Treatment
- Breast Implant and Reconstruction
- Lung Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related Molecular Pathways
- Sarcoma Diagnosis and Treatment
- Medical Imaging Techniques and Applications
University of Belgrade
2015-2025
Oncology Institute of Vojvodina
2016-2025
Institut za onkologiju i radiologiju Srbije
2002-2022
University of Novi Sad
2021
University of Arts in Belgrade
2016
University of Nis
2016
Hospital Clínic de Barcelona
2015
Research Institute of Radiology
2005
Klinički centar Vojvodine
2000
Background: Methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms (SNPs) have been suggested as risk, prognostic, and predictive factors for colorectal cancer in various populations, but not validated so far. The aim of this study was to examine the association MTHFR C677T (rs1801133) A1298C (rs1801131) with risk rectal well response neoadjuvant chemoradiotherapy (nCRT) based on 5-Fluorouracil (5-FU)/leucovorin (LV) locally advanced setting. Patients methods: This...
Background and Objectives: The standard treatment for locally advanced rectal cancer (LARC) includes neoadjuvant chemoradiotherapy (nCRT), followed by surgery with or without adjuvant chemotherapy (CT). This study evaluated the efficacy safety of dose-escalated radiotherapy (RT) using volumetric modulated arc therapy-simultaneous integrated boost (VMAT-SIB) technique in patients LARC compared to 3D conformal (3D-CRT). Materials Methods: prospectively enrolled 75 LARC. All received nCRT...
Background and Objectives: The standard treatment for locally advanced rectal cancer (LARC) includes neoadjuvant chemoradiotherapy (nCRT), followed by surgery with or without adjuvant chemotherapy (CT). This study evaluated the efficacy safety of dose-escalated radiotherapy (RT) using volumetric modulated arc therapy–simultaneous integrated boost (VMAT–SIB) technique in patients LARC compared to 3D conformal (3D-CRT). Materials Methods: prospectively enrolled 75 LARC. All received nCRT...
Introduction: Standard therapy for patients with ovarian cancer involves cytoreductive surgery followed by platinum-based chemotherapy. Factors such as the stage of disease at diagnosis, histological type tumor, size tumor and presence residual after influence prognosis patients. Material methods: This scientific paper presents a retrospective study in which following parameters were analyzed analyzing data obtained from documentation treated Institute Oncology Radiology Serbia Vojvodina:...
(1) Background: This study aimed to develop a machine learning model based on radiomics of pretreatment magnetic resonance imaging (MRI) 3D T2W contrast sequence scans combined with clinical parameters (CP) predict neoadjuvant chemoradiotherapy (nCRT) response in patients locally advanced rectal carcinoma (LARC). The also assessed the impact dimensionality predictive performance. (2) Methods: Seventy-five were prospectively enrolled clinicopathologically confirmed LARC and nCRT before...
Abstract Background Understanding the molecular features associated with response to neoadjuvant chemoradiotherapy is an unmet clinical need in locally advanced rectal cancer (LARC). The aim of study was apply a high-sensitivity proteomic approach for in-depth characterization LARC proteome search patients who might have good preoperative treatment and potentially be followed by watch-and-wait strategy, rather than having immediate surgery, maximizing therapeutic effect quality life. Methods...
Introduction: The standard treatment for locally advanced rectal cancer (LARC) is neoadjuvant chemoradiotherapy (nCRT). To select patients who would benefit the most from nCRT, there a need predictive biomarkers. aim of this study was to evaluate role clinical, pathological, radiological, inflammation-related genetic, and hematological parameters in prediction post-nCRT response. Materials methods: In silico analysis published transcriptomics datasets conducted identify candidate genes,...
Locally advanced rectal cancer (LARC) presents a challenge in identifying molecular markers linked to the response neoadjuvant chemoradiotherapy (nCRT). This study aimed utilize sensitive proteomic method, data-independent mass spectrometry (DIA-MS), extensively analyze LARC proteome, seeking individuals with favorable initial responses suitable for watch-and-wait approach. research addresses unmet need understand treatment, potentially guiding personalized strategies patients....
It is projected that, by 2040, the number of new cases colorectal cancer (CRC) will increase to 3.2 million, and deaths 1.6 highlighting need for prevention strategies, early detection adequate follow-up. In this study, we aimed provide an overview progress in personalized medicine CRC Serbia, with results insights from Institute Oncology Radiology Serbia (IORS), propose guidance tackling observed challenges future.
Abstract Background Historically, the treatment of choice for anal cancer had been abdominoperineal resection (APR). Radical radiotherapy with concurrent 5-fluorouracil plus mitomycin C chemotherapy was later established as standard therapy, although a failure rate 20–30%. The aim this study to evaluate outcomes after radical chemoradiotherapy (CRT), prognostic and predictive factors patterns failure. Patients methods This included 47 patients treated CRT patohistologicaly confirmed squamous...