A5011716445- Cancer-related gene regulation
- Wnt/β-catenin signaling in development and cancer
- Hippo pathway signaling and YAP/TAZ
- Metabolism, Diabetes, and Cancer
- Cancer Mechanisms and Therapy
- Epigenetics and DNA Methylation
- Chemical Reactions and Isotopes
- Galectins and Cancer Biology
Institut Cochin
2018-2019
Université Paris Cité
2018
Centre National de la Recherche Scientifique
2018
Inserm
2018
Délégation Paris 5
2018
Physiologie de la Reproduction et des Comportements
2018
Hepatocellular carcinomas (HCCs) are known to be highly heterogenous. Within the extensive histopathological and molecular heterogeneity of HCC, tumors with mutations in CTNNB1, encoding β-catenin (CTNNB1-mutated HCC), constitute a very homogeneous group. We previously characterized distinctive metabolic histological phenotype for CTNNB1-mutated HCC. They were found well-differentiated, almost never steatotic, often cholestatic, microtrabecular or acinar growth pattern. Here, we investigated...