- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Renal function and acid-base balance
- Nosocomial Infections in ICU
- Patient Safety and Medication Errors
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Heart Failure Treatment and Management
- Antibiotics Pharmacokinetics and Efficacy
- Healthcare Technology and Patient Monitoring
- Quality and Safety in Healthcare
- Medication Adherence and Compliance
- Thermal Regulation in Medicine
- Pneumonia and Respiratory Infections
The University of Sydney
2017-2024
Royal Prince Alfred Hospital
2020-2024
The primary objective was to determine the proportion of hospitals that administered norepinephrine peripheral vasopressor infusions (PVIs) in critically ill adult patients. Secondary objectives were describe how is used such as maximum duration, infusion rate and concentration, most common first-line PVI by country. An international multi-centre cross-sectional survey study conducted intensive care units Australia, US, UK, Canada, Saudi Arabia. Critical pharmacists from 132 institutions...
The aim of this study was to determine the conversion dose ratio between continuous infusion metaraminol and norepinephrine in critically ill patients with shock.A retrospective cohort conducted adult shock admitted an intensive care unit from 29 October 2018 30 2019 who transitioned monotherapy monotherapy. Mean arterial pressure (MAP) doses for both drugs were collected at hourly intervals; 2 hours before 5 after switching defined as (μg.kg-1 .min-1) : .min-1 ) required achieve a similar...
<h3>Objective</h3> There is limited evidence to support metaraminol use in critically ill patients. Metaraminol not included as a vasopressor choice international guidelines for the management of shock. Nevertheless, used rates up 42% this patient population. The objective study was investigate effectiveness treatment patients with <h3>Methods</h3> A single-centre retrospective matched observational conducted 54-bed intensive care unit tertiary hospital. Patients aged 16 years or older who...
Background: There is little known about antibiotic de-escalation (ADE) practices in the intensive care unit (ICU). Objective: The objective was to determine proportion of patients who received ADE within 24 hours actionable cultures and identify predictors timely ADE. Methods: Multicenter cohort study ICUs 15 hospitals Australia New Zealand. Adult were included if they started on broad-spectrum antibiotics ICU admission. defined as switching from a agent narrower-spectrum or cessation....
Introduction: Initial empiric broad-spectrum antibiotics for sepsis should be followed by antimicrobial de-escalation (ADE) when possible, to minimize patient harm and the development of resistance. The primary objective this study was determine proportion patients who received ADE within 24 hours definitive culture results. Methods: This a multicenter, retrospective cohort conducted in intensive care units (ICU) 15 hospitals Australia New Zealand. Consecutive medical records admitted ICU...