A5037888832- Metabolomics and Mass Spectrometry Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Cancer, Lipids, and Metabolism
- Cancer therapeutics and mechanisms
- Lung Cancer Treatments and Mutations
- Pharmaceutical and Antibiotic Environmental Impacts
- Diet and metabolism studies
- Antibiotic Resistance in Bacteria
- Hepatitis C virus research
- Antibiotics Pharmacokinetics and Efficacy
- Tryptophan and brain disorders
- Autoimmune and Inflammatory Disorders Research
- Rheumatoid Arthritis Research and Therapies
- Bioinformatics and Genomic Networks
Sechenov University
2022-2025
Ministry of Health of the Russian Federation
2024
Abstract Lung cancer is referred to as the second most common worldwide and mainly associated with complex diagnostics absence of personalized therapy. Metabolomics may provide significant insights into improvement lung through identification specific biomarkers or biomarker panels that characterize pathological state patient. We performed targeted metabolomic profiling plasma samples from individuals non-small cell (NSLC, n = 100) without any chronic pathologies (n identify relationship...
Metabolomics is a promising technology for the application of translational medicine to cardiovascular risk. Here, we applied liquid chromatography/tandem mass spectrometry approach explore associations between plasma concentrations amino acids, methylarginines, acylcarnitines, and tryptophan catabolism metabolites cardiometabolic risk factors in patients diagnosed with arterial hypertension (HTA) (n = 61), coronary artery disease (CAD) 48), non-cardiovascular (CVD) individuals 27). In...
Abstract Lung cancer is referred to as the second most common worldwide and mainly associated with poor diagnostics absence of personalized therapy. Metabolomics may provide significant insights into improvement lung treatment through identification specific biomarkers or biomarker panels that characterize pathological state patient. We performed targeted metabolomic profiling plasma samples from individuals non-small cell (NSLC, n = 100) without any chronic pathologies (n identify...
Prevalent drug resistance of pathogenic bacteria is a major concern for healthcare. Decreased bacterial susceptibility to antibiotics reduces treatment efficiency, putting lives patients at risk. To overcome this issue, novel anti-virulence Fluorothiazinon (FT) was developed. The inhibits type three secretion system and flagella motility many Gram-negative bacteria. It showed therapeutic activity against number microorganisms, such as Pseudomonas aeruginosa, Acinetobacter baumannii,...