A5030352502- Renal Transplantation Outcomes and Treatments
- Renal Diseases and Glomerulopathies
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Complement system in diseases
- Blood groups and transfusion
Aristotle University of Thessaloniki
2022-2024
Ippokrateio General Hospital of Thessaloniki
2024
Hippocration General Hospital
2023
Chronic kidney disease is associated with immunological disorders, presented as phenotypic alterations of T lymphocytes. These changes are expected to be restored after a successful renal transplantation; however, additional parameters may contribute this process.To evaluate the impact positive panel reactive antibodies (PRAs) on restoration cell phenotype, transplantation.CD4CD28null, CD8CD28null, natural killer cells (NKs), and regulatory (Tregs) were estimated by flow cytometry at T0, T3,...
Abstract Background and Aims Two semiquantitative single-antigen bead (SAB) methods are currently available for the detection of anti-HLA antibodies estimation their activity, depending on complement binding. However, data accordance two specificities reactivity evaluation scarce. The purpose this study is to compare in terms binding capacity Method Sera from 97 patients with a positive Panel Reactive Antibody Test (>5%) was tested by SAB methods, Immucor (IC) One-lambda (OL), class I...
: The purpose of this study was to evaluate numerical changes in immune cells after successful kidney transplantation and associate their recovery with clinical laboratory factors.
Two semi-quantitative, Luminex-based, single-antigen bead (SAB) assays are available to detect anti-HLA antibodies and evaluate their reactivity with complement binding. Sera from 97 patients positive panel reactive antibody tests (>5%) were analyzed two SAB tests, Immucor (IC) One-Lambda (OL), for detection the evaluation of complement-binding capacity. IC detected 1608/8148 (mean fluorescent intensity (MFI) 4195 (1995-11,272)) 1136/7275 (MFI 6706 (2647-13,184)) class I II specificities,...