A5093521388- Renal Transplantation Outcomes and Treatments
- Complement system in diseases
- Animal Virus Infections Studies
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- SARS-CoV-2 and COVID-19 Research
- Renal Diseases and Glomerulopathies
Hippocration General Hospital
2023-2024
: The purpose of this study was to evaluate numerical changes in immune cells after successful kidney transplantation and associate their recovery with clinical laboratory factors.
Multiple vaccinations have potential inimical effects on the immune system aging process. We examined whether response to SARS-CoV-2 vaccination with Tozinameran is associated immunosenescence and immunoexhaustion in kidney transplant recipients (KTRs).
Two semi-quantitative, Luminex-based, single-antigen bead (SAB) assays are available to detect anti-HLA antibodies and evaluate their reactivity with complement binding. Sera from 97 patients positive panel reactive antibody tests (>5%) were analyzed two SAB tests, Immucor (IC) One-Lambda (OL), for detection the evaluation of complement-binding capacity. IC detected 1608/8148 (mean fluorescent intensity (MFI) 4195 (1995-11,272)) 1136/7275 (MFI 6706 (2647-13,184)) class I II specificities,...