Quantitative and multiparametric blood analysis is of great clinical importance in cardiovascular disease diagnosis. Although there are various methods to extract information, they often require invasive procedures, lack continuity, involve bulky instruments, or have complicated testing procedures. Flexible sensors can realize on-skin assessment several vital signals, but generally exhibit limited function monitor characteristics. Here, we report a flexible optoacoustic 'stethoscope' for...

A handheld approach to 3D photoacoustic imaging is essential in clinical applications. To this end, we develop a imager for dynamic (temporally and spatially) volumetric visualization. In imager, the optically transmitting part acoustically receiving are integrated into single probe with compact size about 160 mm ×64 ×40 mm. Besides, dedicated reconstruction algorithm heterogeneous medium developed based on phase-shift migration method frequency domain, which deals well stratified condition...

Acoustic resolution photoacoustic microscopy (AR-PAM) is a promising medical imaging modality that can be employed for deep bio-tissue imaging. However, its relatively low has greatly hindered wide applications. Previous model-based or learning-based PAM enhancement algorithms either require design of complex handcrafted prior to achieve good performance lack the interpretability and flexibility adapt different degradation models. model AR-PAM subject both depth center frequency ultrasound...

A novel coil-based electromagnetic-induced thermo-acoustic system is presented for detecting the flaws inside a rail. The fundamental derived and overall energy density distribution simulated using finite element method. This paper gives an overview of architecture describes design process in detail. mixed numerical experimental methodology employed to extract lumped parameters planar coil with ferrite plate designing matching network, then rail are co-simulated observe current distributions...

Malaria parasite- <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Plasmodium falciparum</i> infection is a severe healthcare problem in tropical and subtropical regions. Early detection of such disease vital reducing mortality controlling the spread affected areas. In this article, detecting ring-stage malaria parasite carried out by using proposed photoacoustic (PA)-surface acoustic wave (SAW) sensing system. By optical radiation, PA signal...

Acoustic resolution photoacoustic micros- copy (AR-PAM) can achieve deeper imaging depth in biological tissue, with the sacrifice of compared optical microscopy (OR-PAM). Here we aim to enhance AR-PAM image quality towards OR-PAM image, which specifically includes enhancement resolution, restoration micro-vasculatures, and reduction artifacts. To address this issue, a network (MultiResU-Net) is first trained as generative model simulated AR-OR pairs, are synthesized physical transducer...

In recent years, photoacoustic image reconstruction has received extensive attention. Various methods, such as back-projection, frequency domain reconstruction, time reversal, and model-based reconstructions have been developed. Although these methods are based on different propagation theories, they relatively simple implementations when reconstructing images homogenous media. However, in cases of heterogeneous layered media, like transcranial imaging, the models to be modified accommodate...

For precise health status monitoring and accurate disease diagnostics in the current COVID-19 pandemic, it is essential to detect various kinds of target signals robustly under high noise strong interferences. Moreover, system preferred be realized a small form factor for convenient mass deployments. A CMOS-integrated coherent sensing platform proposed achieve goal, which synergetically leverages quadrature photoacoustic (PA) detection radar achieving universal healthcare. By utilizing...

Photoacoustic Microscopy (PAM) optical resolution (OR) imaging method is suited to get high bio-tissue image but suffers from shallow penetration depth. By contrast, photoacoustic acoustic (AR) has deeper depth with degraded resolution. Inspired by the current advances in field of deep neural network (DNN), we proposed a new DNN framework named Prior Residual U-Net (PRU-Net), which combines global residual block and prior for AR OR enhancement. It helps aggregate advantages both methods...

Diabetic patients need long-term and frequent glucose monitoring to assist in insulin intake. The current finger-prick devices are painful costly which make noninvasive sensors highly demanded. In this review paper, we discuss several advanced electromagnetic (EM) wave based technologies for measurement, including infrared (IR) spectroscopy, photoacoustic (PA) Raman fluorescence, optical coherent tomography (OCT) microwave sensing. Development progress of each method discussed regarding...

Acoustic resolution photoacoustic microscopy (AR-PAM) is a non-invasive medical imaging modality that can be employed for deep bio-tissue and vasculature imaging. However, to achieve clinical translation, system improvements algorithmic techniques are still required further enhance the performance. In this paper, hardware modules of specifically analyzed, then typical AR-PAM its miniaturized counterparts have also been demonstrated. Furthermore, optical acoustic simulation proposed...

Optical resolution photoacoustic microscopy (OR-PAM) imaging method can achieve high lateral $(\lt 5 \mu \mathrm{m})$, while the penetration depth for OR is shallow (up to $1 \sim 2$ mm). In contrast, acoustic (AR-PAM) only has limited $(\gt 50 \mathrm{m})$ but with deeper up several millimeters (3-10 Enlighted by recent progress in field of machine learning, we proposed enhance AR-PAM OR-PAM maintaining its merit deep neural network, where a novel network structure named MultiResU-Net...

As a novel biomedical imaging setup, acoustic resolution photoacoustic microscopy (AR-PAM) employs effect for visualizing vasculature and bio-structure. Nevertheless, this modality suffers from low which greatly limited the application clinical usage. Model based data driven algorithms have been developed to enhance quality, however, there exists limitations in both kinds of respectively. In paper, we proposed Plug Play prior regularized AR-PAM enhancement algorithm, combined merits model...

Photoacoustic (PA) imaging is becoming more attractive because it can obtain high-resolution and high-contrast images through merging the merits of optical acoustic imaging. High sensitivity receiver required in deep in-vivo PA due to detecting weak noisy ultrasound signal. A novel photoacoustic system-on-chip (SoC) with coherent detection (CD) based on early-and-late acquisition tracking developed first fabricated. In this system, a signal negative signal-to-noise-ratio (SNR) be clearly...

We introduce a compact, non-contact multimodal imaging platform that integrates ultrasound (US) imaging, inclusive of photoacoustic (PA) detection, with optical coherence tomography (OCT). This integration is achieved through novel virtual acoustic detector array (VADA) technique for all-optical US sensing, utilizing the temporal and spatial resolving capabilities swept-source interferometry. The extracts signals from phase time evolution OCT's spectral sweep. It enables construction VADA...

Coil designs and associated circuits for wireless power transfer have been extensively studied. This paper introduces the fundamentals of application in rail, investigates transmitting coils with different conical angles obtains magnetic field intensity distributions at various lift-off distances between coil rail. An equivalent circuit model is built to illustrate relationship Then finally, thermoacoustic generated inside rail verified through experiment.

Photoacoustic endoscopy (PAE), combining both advantages of optical contrast and acoustic resolution, can visualize the chemical-specific information tissues inside human-body. Recently, its corresponding reconstruction methods have been extensively researched. However, most them are limited on cylindrical scan trajectories, rather than a helical which is more clinically practical. On this note, article proposes methodology imaging evaluation for guided PAE. Different from traditional...

Acoustic-resolution microscopy is an important imaging method in studying biological tissues with deep penetration. Using high-frequency transducer could reduce the size of acoustic focal spot, thereby improving resolution microscopy. However, photoacoustic signals usually suffer from attenuation which weakens their energy and distorts image. In this paper, compensation for acoustic-resolution proposed. This technique upgrades wavenumber term by considering dispersion during wavefield...