Olivia Edwards

ORCID: 0000-0001-8753-9348
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About
Contact & Profiles
Research Areas
  • Cutaneous Melanoma Detection and Management
  • Cancer Genomics and Diagnostics
  • Bioinformatics and Genomic Networks
  • Computational Drug Discovery Methods
  • Melanoma and MAPK Pathways

Wellcome Sanger Institute
2021-2022

Abstract Combinations of anti-cancer drugs can overcome resistance and provide new treatments 1,2 . The number possible drug combinations vastly exceeds what could be tested clinically. Efforts to systematically identify active the tissues molecular contexts in which they are most effective accelerate development combination treatments. Here we evaluate potency efficacy 2,025 clinically relevant two-drug combinations, generating a dataset encompassing 125 molecularly characterized breast,...

10.1038/s41586-022-04437-2 article EN cc-by Nature 2022-02-23
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