A5059964259- Parasites and Host Interactions
- Research on Leishmaniasis Studies
- Mosquito-borne diseases and control
- CRISPR and Genetic Engineering
- Insect symbiosis and bacterial influences
- Biochemical and Molecular Research
- Computational Drug Discovery Methods
- Parasite Biology and Host Interactions
- Mollusks and Parasites Studies
Chinhoyi University of Technology
2021-2022
Schistosomiasis is a neglected tropical disease affecting over 250 million people worldwide. The the second most prevalent after malaria. Treatment of schistosomiasis relies on administration praziquantel (also known as biltricide). Reliance single drug poses threat to public health system parasite may become resistant shown by some laboratory findings. possibility resistance rising clinically significant levels has motivated scientific community search for new nominees. For long time,...
Reports of snails' resistance to niclosamide appeared recently and finding new molluscicides becomes necessary. We investigated the molluscicidal effects Cucurbita maxima seed extracts on Biomphalaria pfeifferi, Bulinus globosus snails under laboratory conditions. For B. we tested juvenile adult while only were available for testing. Snails exposed water crude ethanol 72 h significant concentration-dependent mortality rates observed. The number pfeifferi juveniles collected was not enough a...
Schistosomiasis, a disease usually related to poverty and poor sanitation, affects more than 200 million people worldwide. Since the 1970s, medical sector has depended on single drug, praziquantel, for treatment of disease. The emerging evidence resistance Schistosoma parasite praziquantel drug's inefficacy against juvenile stages makes need find alternative drugs an urgent matter. In this study, we explored inhibition potential compounds from Cucurbita maxima using molecular docking studies...
Gene drives are being used to enhance a DNA sequence's likelihood of passing between generations via sexual reproduction. can be deployed manipulate natural populations. They suppress populations by reducing the number individuals in population or modify There more than 3000 mosquito species world, some which vectors diseases. Malaria is typical disease whose mosquitoes. It affects mostly tropical countries. kills many people annually, whom children. Interventions currently use, such as...