A5053390489- CRISPR and Genetic Engineering
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Cancer Mechanisms and Therapy
- Multiple Myeloma Research and Treatments
- Mosquito-borne diseases and control
- Cancer, Stress, Anesthesia, and Immune Response
- Bioeconomy and Sustainability Development
- vaccines and immunoinformatics approaches
- Immunotherapy and Immune Responses
- Virus-based gene therapy research
- RNA Interference and Gene Delivery
- Biotechnology and Related Fields
- African history and culture analysis
- Dermatology and Skin Diseases
- Hepatocellular Carcinoma Treatment and Prognosis
- Immune cells in cancer
- Advanced biosensing and bioanalysis techniques
- Genetics, Bioinformatics, and Biomedical Research
- Transgenic Plants and Applications
- Electrospun Nanofibers in Biomedical Applications
- Vector-borne infectious diseases
- Plant Reproductive Biology
- SARS-CoV-2 and COVID-19 Research
- Insect symbiosis and bacterial influences
Midlands State University
2018-2025
Guangzhou Institutes of Biomedicine and Health
2020-2023
State Key Laboratory of Respiratory Disease
2021-2023
Chinese Academy of Sciences
2021-2023
Lupane State University
2020
Tehran University of Medical Sciences
2016-2018
University of Tehran
2018
The role of albumin-based biomaterials in tissue engineering (TE) cannot be overemphasized. authors review the albumin lungs scaffold grafting, which promotes cell seeding. Albumin grafted on decellularized is presented as a great support material for cell-tissue interaction well ease attachment, growth, and differentiation when seeded with different types cells. fabrication from sources promising approach that may facilitate medical treatments bench-to-bed, although this surfactant proteins...
House dust mite (HDM) allergens are important elicitors of IgE-mediated allergies. This study was aimed at constructing and characterizing a recombinant fusion protein, DpTTDp, which based on carrier-bound Der p 1-derived peptides for HDM allergen immunotherapy.Using the Immune Epitope Database (IEDB), we identified from 1, 34-mer hypoallergenic peptide. Two copies hypoallergen were then fused to partial fragment tetanus toxoid molecule's N-and C terminus expressed in Escherichia coli. After...
Postoperative recurrence causes a high mortality rate among patients with hepatocellular carcinoma (HCC). The current study aimed to determine the effects of Plasmodium infection on HCC metastasis and recurrence. antitumor were determined using two murine orthotopic models: non‑resection model resection model. Tumour tissues derived from tumour‑bearing mice treated or without harvested 15 days post‑tumour inoculation. expression levels biomarkers related epithelial‑mesenchymal transition...
Our previous studies have demonstrated that Plasmodium immunotherapy (infection) has antitumor effects in mice. However, as a new form of immunotherapy, this therapy weakness: its specific killing effect on tumor cells is relatively weak. Therefore, we tested whether combined with gemcitabine (Gem), representative chemotherapy drug, synergistic effects.We designed subcutaneously and intravenously implanted murine Lewis lung cancer (LLC) models to test the chabaudi ASS (Pc) infection...
House dust mite (HDM) allergy is the leading cause of IgE-mediated hypersensitivity. Therefore identifying potential epitopes in Dermatophagoide pteronyssinus 23 (Der p 23), a major house allergen will aid development therapeutic vaccines and diagnostic kits for HDM allergy. Experimental methods epitope discovery have been widely exploited mapping allergens. This study sought to use immunoinformatic analyze structure Der immunoreactive B T-cell that could be useful AIT diagnosis. We...
Synthetic biology (SynBio) is an interdisciplinary field that has developed rapidly in the last two decades. It involves design and construction of new biological systems processes from standardized components, networks synthetic pathways. The goal Synbio to create logical forms cellular control. Biological their parts can be redesigned carry out completely functions. SynBio poised greatly impact human health, environment, biofuels chemical production with huge economic benefits. presents...
Gene drives are being used to enhance a DNA sequence's likelihood of passing between generations via sexual reproduction. can be deployed manipulate natural populations. They suppress populations by reducing the number individuals in population or modify There more than 3000 mosquito species world, some which vectors diseases. Malaria is typical disease whose mosquitoes. It affects mostly tropical countries. kills many people annually, whom children. Interventions currently use, such as...
Abstract Human telomerase reverse transcriptase (hTERT) is the most common tumor-associated antigen (TAA) and its activity upregulated in more than 90% of cancers. Therefore, targeting can be used cancer immunotherapy. In continuing with our previous study, we evaluated hTERT derived peptides conjugated to KLH mice breast models. To induce tumors Balb/C mice, about 5 × 10 4T1 cell were washed suspended 100 µl sterile PBS subcutaneously (s.c) injected 4th mammary fat pat 6–8 weeks old mice....
Synthetic biology (SynBio) is an interdisciplinary field that has developed rapidly in the last two decades. It involves design and construction of new biological systems processes from standardized components, networks synthetic pathways. The goal Synbio to create logical forms cellular control. Biological their parts can be re-designed carry out completely functions. SynBio poised greatly impact human health, environment, biofuels chemical production with huge economic benefits. presents...
Abstract Human telomerase reverse transcriptase (hTERT) is the most common tumor-associated antigen (TAA) and its activity upregulated in more than 90% of cancers. Therefore, targeting could be used cancer immunotherapy. In continuing with our previous study, we evaluated hTERT derived peptides conjugated to KLH mice breast models. To induce tumors Balb/C mice, about 5 × 10 4T1 cell were washed suspended 100 μl sterile PBS subcutaneously (s.c) injected 4 th mammary fat pat 6-8 weeks old...
Gene drives in malaria control: What we need to know aReagan Mudziwapasi*, bMunyaradzi Christopher Changara, aAbigarl Ndudzo, bTinotenda Kaseke, Farai Godobo, cRyman Shoko, dFanuel Songwe, aSakhile Ndlovu and bSandra Sibonani MlamboaDepartment of Crop Soil Sciences (Applied Biotechnology Program), Lupane State University, P. O. Box 170, Lupane, ZimbabwebDepartment Biotechnology, Chinhoyi University Technology, 7724, Chinhoyi, ZimbabwecDepartment Biology, ZimbabwedDepartment Biosciences...
Abstract Background : Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer mortality worldwide and characterized by a high rate recurrence. We have previously reported Plasmodium infection inhibits tumor development metastasis in murine Lewis lung model. In current study, we aimed to examine effects on HCC Methods Antitumor were determined using two orthotopic models, non-resection model for investigating effect liver progression metastasis, resection recurrence after was...