A5053504786- Educational Research and Pedagogy
- EFL/ESL Teaching and Learning
- Acute Kidney Injury Research
- Digital Storytelling and Education
- Education and Learning Interventions
- Dialysis and Renal Disease Management
- Educational Systems and Policies
- Central Venous Catheters and Hemodialysis
- Second Language Acquisition and Learning
- Education and Critical Thinking Development
- Chronic Kidney Disease and Diabetes
- Educational Methods and Media Use
- Educational Practices and Challenges
- Chemotherapy-induced organ toxicity mitigation
- Body Composition Measurement Techniques
- Renal and Vascular Pathologies
- Education, Safety, and Science Studies
- Nutrition and Health in Aging
- Natural Language Processing Techniques
- biodegradable polymer synthesis and properties
- Muscle and Compartmental Disorders
- Vascular Procedures and Complications
- Dental materials and restorations
- Second Language Learning and Teaching
- Pharmacological Effects and Toxicity Studies
Chungnam National University
2017-2025
Chungnam National University Hospital
2015-2023
Sungkyunkwan University
2019-2021
Kangwon National University
2020-2021
ORCID
2020
Kyungpook National University
2017
Gangneung–Wonju National University
2016
Korea University of Technology and Education
2013-2014
Seoul National University of Education
2011-2013
Advanced Energy Materials (United States)
2013
Background: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.This disease, which quickly spreading worldwide, has high potential for infection and causes rapid progression of lung lesions, resulting in a mortality rate.This study aimed to investigate the effects SARS-CoV-2 on renal function patients with COVID-19.Methods: From February 21 April 24, 2020, 66 diagnosed COVID-19 at Chungnam National University Hospital were...
Hepatic fibrosis is characterized by persistent deposition of extracellular matrix proteins and occurs in chronic liver diseases. The aim the present study to investigate whether estrogen deficiency (ED) potentiates hepatic a thioacetamide (TAA)-treated rat model. Fibrosis was induced via intraperitoneal injection (i.p.) TAA (150 mg/kg/day) for four weeks ovariectomized (OVX) female, sham-operated or male rats. In TAA-treated OVX rats, activities serum alanine aminotransferase (ALT),...
For reducing the high mortality rate of severe acute kidney injury (AKI) patients initiating continuous renal replacement therapy (CRRT), diagnosing sepsis and predicting prognosis are essential. However, with reduced function, biomarkers for unclear. This study aimed to assess whether C-reactive protein (CRP), procalcitonin, presepsin could be used diagnose predict in impaired function CRRT. was a single-center, retrospective involving 127 who initiated Patients were divided into non-sepsis...
Background/Aims: The kidneys and retina are highly vascularized organs that frequently exhibit shared pathologies, with nephropathy often associated retinopathy. Previous studies have successfully predicted estimated glomerular filtration rates (eGFRs) using fundus photographs. We evaluated the performance of Modification Diet in Renal Disease (MDRD) Chronic Kidney Epidemiology Collaboration (CKD-EPI) formulas eGFR prediction.Methods: enrolled patients photographs corresponding creatinine...
Benzo[a]pyrene (BaP) is a well-known carcinogen formed during the cooking process. Although BaP exposure has been implicated as one of risk factors for lung cancer in animals and humans, there are only limited data on BaP-induced gastrointestinal cancer. Therefore, this study investigated protective effects curcumin DNA damage rat stomach tissues. (20 mg/kg/day) (50, 100, or 200 mg/kg) were administered daily to Sprague-Dawley rats by oral gavage over 30 days. Curcumin was pre-administered...
The aquatic extract of Dendropanax morbifera (DP) is typically consumed as a beverage in Korea and China also used various traditional medicines. However, the functional role DP on diabetes-induced renal fibrosis unclear. Here, protective effects against were evaluated. Streptozotocin (STZ, 60 mg/kg) was injected intraperitoneally rats to induce diabetes. After 5 days, (25 mg/kg/day) metformin (50 administered orally diabetic for 28 days. administration protected both body organ weight loss...
Renal disease associated with type 2 diabetes mellitus (T2DM) has become the leading cause of chronic kidney (CKD). ultrasonography is an imaging examination required in work-up renal disease. This study aimed to identify differences ultrasonographic findings between patients and without DM, evaluate relationship ultrasound prognosis DM. A total 252 who underwent at Chungnam National University Hospital were included. Kidney progression was defined as a ≥10% decline annual estimated...
To investigate whether high-intensity focused ultrasound (HIFU) combined with microbubbles enhances the therapeutic effects of chemotherapy. A pancreatic cancer xenograft model was established using BALB/c nude mice and luciferase-expressing human cells. Mice were randomly assigned to five groups according treatment: control (n = 10), gemcitabine alone (GEM; n 12), HIFU (HIFU + MB, 11), (HIGEM; HIGEM MB 13). After three weekly treatments, apoptosis rates evaluated terminal deoxynucleotidyl...
We investigated possible conditions or drugs that could target P-glycoprotein (P-gp)-overexpressing drug-resistant KBV20C cancer cells. Specifically, we focused on identifying a single treatment with relatively low half maximal inhibitory concentration (IC50). Our approach utilized repurposing drugs, which are already used in clinical practice. evaluated 13 TKIs (gefitinib, imatinib, erlotinib, nilotinib, pazopanib, masatinib, sunitinib, sorafenib, regorafenib, lapatinib, vandetanib,...
Use of the chemotherapeutic agent cisplatin (CDDP) in cancer patients is limited by occurrence acute kidney injury (AKI); however, no protective therapy available. We aimed to investigate renoprotective effects Dendropanax morbifera water extract (DM) on CDDP-induced AKI. Male Sprague-Dawley rats (six animals/group) received: Vehicle (control); CDDP (6 mg/kg, intraperitoneally (i.p.); DM (25 oral); or + injection. treatment significantly increased blood urea nitrogen (BUN), serum creatinine...
To determine the optimal timing for post space preparation of root canals sealed with epoxy resin-based AH Plus sealer in terms its polymerization and influence on apical leakage.
Cognitive dysfunction is more frequent in end-stage renal disease (ESRD) patients undergoing hemodialysis compared with the healthy population, emphasizing need for early detection. Interest serum markers that reflect cognitive function has recently increased. Elevated growth differentiation factor 15 (GDF-15) levels are known to be associated an increased risk of decreased and dysfunction. This study investigated relationship between GDF-15 using a retrospective analysis 92 individuals aged...
Hyun Jin Kim, M.D., Ph.D., Manmyung Hyunjae Zhang, M.E., Hae Ri Jae Wan Jeon, Yuri Seo, and Qute Choi, Ph.D.. Ann Lab Med -0001;0:. https://doi.org/10.3343/alm.2024.0304
Knowledge of the proper dry weight plays a critical role in efficiency dialysis and survival hemodialysis patients. Recently, bioimpedance spectroscopy(BIS) has been widely used for set However, BIS is often misrepresented clinical healthy weight. In this study, we tried to predict clinically (DWCP) using machine learning patient's information including BIS. We then analyze factors that influence prediction weight.As retrospective, single center data 1672 patients were reviewed. DWCP...
Background: Cushing syndrome is characterized by glucose intolerance, cardiovascular disease, and an enhanced systemic inflammatory response caused chronic exposure to excess cortisol.Eosinopenia frequently observed in patients with adrenal syndrome, but the relationship between eosinophil count peripheral blood indicators of level has not been determined.Methods: A retrospective study was undertaken clinical laboratory findings 40 diagnosed at Chungnam National University Hospital from...
The photocatalytic production of hydrogen from water using solar energy is potentially a clean and renewable source for fuel. This study examines the over In, P-TiO 2 s photocatalysts. 1 mol% In-TiO were produced solvothermal method treated at 500 800 ∘ C to obtain anatase rutile structure, respectively. photocatalysts characterized by X-ray diffraction, photoluminescence spectra, spectroscopy, UV-visible scanning electron microscopy. H methanol photodecomposition was greater structure than...
The aim of this study was to investigate changes in the intracellular metabolism resulting from cisplatin (CDDP)-induced nephrotoxicity normal kidney tubular epithelial NRK-52E cells. Cytotoxicity, cell cycle analysis, and apoptotic death were all evaluated cells treated with CDDP. Subsequently, proton nuclear magnetic resonance (1H-NMR) spectroscopy used cellular metabolic profiles. CDDP-induced determined vivo model. Cytotoxicity significantly rose following treatment CDDP these increases...
A 68-year-old man presented at the emergency room with sudden blindness. The day before, he had eaten sashimi and eel drank alcohol for dinner. He experienced nausea, vomiting, dizziness afterward. His medical history included hypertension diabetes, latter was treated metformin. Initial laboratory tests revealed severe metabolic acidosis (lactic acidosis). Massive hydration intravenous sodium bicarbonate replacement therapies were initiated, but acidosis) did not resolve, in turn, leading to...