- Nanoplatforms for cancer theranostics
- Immunotherapy and Immune Responses
- Nanoparticle-Based Drug Delivery
- Immune cells in cancer
- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- Extracellular vesicles in disease
- Photoacoustic and Ultrasonic Imaging
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
KU Leuven
2020-2025
Over the past decades, medical exploitation of nanotechnology has been largely increasing and finding its way into translational research clinical applications. Despite their biomedical potential, uncertainties persist regarding intricate role that nanomaterials may play on altering physiology in healthy diseased tissues. Extracellular vesicles (EVs) are recognized as an important pathway for intercellular communication known to be mediators cellular stress. EVs currently explored targeted...
Abstract Cancer immunotherapy is often hindered by an immunosuppressive tumor microenvironment (TME). Various strategies are being evaluated to shift the TME from immunologically ‘cold’ ‘hot’ and hereby improve current immune checkpoint blockades (ICB). One particular hot topic use of combination therapies. Here, we set out screen a variety metallic nanoparticles explored their in-vitro toxicity against series non-tumor cell lines. For silver nanoparticles, also effects core size surface...
Cancer immunotherapy is often hindered by an immunosuppressive tumor microenvironment (TME). Various strategies are being evaluated to shift the TME from immunologically 'cold' 'hot' and hereby improve current immune checkpoint blockades (ICB). One particular hot topic use of combination therapies. Here, we set out screen a variety metallic nanoparticles explored their in vitro toxicity against series non-tumor cell lines. For silver nanoparticles, also effects core size surface chemistry on...