Tomoko Horie

ORCID: 0000-0001-8799-827X
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About
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Research Areas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Colorectal Cancer Treatments and Studies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Nutrition and Health in Aging
  • Colorectal Cancer Surgical Treatments
  • GABA and Rice Research
  • Ear and Head Tumors
  • Noise Effects and Management
  • Colorectal Cancer Screening and Detection
  • Frailty in Older Adults
  • Sesame and Sesamin Research
  • Head and Neck Surgical Oncology
  • Animal Nutrition and Physiology
  • Multiple and Secondary Primary Cancers
  • Ocular Oncology and Treatments
  • Multiple Myeloma Research and Treatments
  • Cancer Diagnosis and Treatment
  • Abdominal Surgery and Complications
  • Hearing Loss and Rehabilitation
  • Genetic factors in colorectal cancer
  • Esophageal and GI Pathology
  • Salivary Gland Tumors Diagnosis and Treatment
  • Abdominal vascular conditions and treatments
  • Peptidase Inhibition and Analysis

Tokyo National Hospital
2020-2022

National Cancer Center Hospital East
2021

National Center for Global Health and Medicine
2016

Center for Global Health
2016

Children's Medical Center
2007

Toyota Memorial Hospital
2003

Abstract Background Assessment of preoperative general condition to predict postoperative outcomes is important, particularly in older patients who typically suffer from various comorbidities and exhibit impaired functional status. In addition indices such as Charlson Comorbidity Index (CCI), National Institute on Aging Cancer (NIA/NCI), Adult Evaluation-27 (ACE-27), American Society Anesthesiologists Physical Status classification (ASA-PS), controlling nutritional status (CONUT) score...

10.1186/s12885-019-6218-8 article EN cc-by BMC Cancer 2019-11-06

Pseudomyxoma peritonei (PMP) is a rare disease with an estimated incidence of 1–2 cases per million individuals year. PMP characterized by the accumulation abundant mucinous or gelatinous fluid derived from disseminated tumorous cells. Most cells are originated rupture appendiceal neoplasms, but some metastasis cancer colon, ovary, fallopian tube, urachus, colorectum, gallbladder, stomach, pancreas, lung and breast. Although frequent mutations in KRAS and/or GNAS genes have been reported,...

10.1186/s12881-016-0356-5 article EN cc-by BMC Medical Genetics 2016-12-01

The feasibility of laparoscopic surgery for elderly patients remains unclear, as these usually present with comorbidities. Recently, the controlling nutritional status (CONUT) score has drawn attention an evaluation patients’ general well a predictor survival. We retrospectively analyzed overall survival in 424 aged ≥75 years colon cancer, who underwent curative (laparoscopic (n = 167) or open 257)) between January 2004 and December 2013. To adjust heterogeneity both groups, propensity...

10.1080/01635581.2020.1743868 article EN Nutrition and Cancer 2020-04-07

Although right-sided colon cancer is increasingly recognized as having a worse prognosis than left-sided colorectal for liver metastases, little known about the differences between and rectum.This study evaluated prognostic value of primary tumor location in patients with metastases by examining rectum separately.This was retrospective from 2003 to 2017.The conducted National Cancer Center Hospital.The cohort included 489 ( n = 119, 24%), 251, 51%), or rectal 24%) who underwent hepatic...

10.1097/dcr.0000000000002228 article ES Diseases of the Colon & Rectum 2021-12-30

平成17年度, 新生児聴覚スクリーニングより精査目的に紹介された50例について, 受診前後の診断過程, 結果を検討した。50例中, 両側難聴が22例, うち21例が補聴器装用となった。一側難聴は19例, 両側正常が9例であった。診断方法は月齢, 紹介元の検査結果などに応じてBOA・COR・DPOAE・ABR/ASSRを組み合わせて行い, 高度難聴ではおおよそ6ヵ月, 中等度難聴では8.2ヵ月で補聴器装用となった。

10.4295/audiology.50.211 article EN AUDIOLOGY JAPAN 2007-01-01

本研究では,抗酸化成分(ゴマリグナン類およびビタミンE)を有するゴマに着目し,すりゴマの給与が肥育後期豚の発育と肉質に及ぼす影響を調査するため2つの実験を実施した。実験1では,LWD豚12頭を6頭ずつ(去勢3頭·雌3頭)2区に分け,対照区飼料(トウモロコシ80%含有)およびすりゴマ区飼料(トウモロコシ77%,すりゴマ3%含有)を給与して,体重66kgから114kgまでの肥育試験を行った。実験2では,LWD豚12頭を6頭ずつ(去勢3頭·雌3頭)2区に分け,対照区飼料(トウモロコシ40%,飼料用玄米40%含有)およびすりゴマ区飼料(トウモロコシ37%,飼料用玄米40%,すりゴマ3%含有)を給与して,体重64kgから110kgまでの肥育試験を行った。実験1,2共に,飼育期間中の増体や飼料摂取量に有意な差は認められなかった。と畜解体後に胸最長筋を採取し,豚肉の理化学特性の分析を行ったところ,実験1,2共にすりゴマ区の豚において背部内層脂肪中のリノール酸の割合が有意に高くなり(P<0.05),γ-トコフェロール量が増加した(P<0.05)。また実験1では,すりゴマを給与した全頭の豚で,背部...

10.5938/youton.54.3_109 article JA Nihon Yoton Gakkaishi 2017-01-01

症例は77歳の男性で,意識障害・ショックを主訴に救急搬送された.精査中に血圧低下を来し,CTにて盲腸から上行結腸にかけて造強効果の減弱を伴う浮腫性壁肥厚を認め非閉塞性腸間膜虚血症(non-occlusive mesenteric ischemia;以下,NOMIと略記)が疑われた.腸管壊死が否定できなかったことより開腹術を施行した.盲腸と上行結腸には虚血を認めるものの壊死を認めなかったため切除は行わずに閉腹した.術後ただちに血管造影検査を行い,上腸間膜動脈からの塩酸パパベリン選択的動注療法を開始した.術翌日には上腸間膜血流は著明な改善を認めた.血管拡張薬の持続動注療法導入を前提として術式決定を行ったNOMIの報告はまれであり報告する.

10.5833/jjgs.2015.0202 article JA The Japanese Journal of Gastroenterological Surgery 2016-01-01

A rare case of recurrent pleomorphic adenoma temporal bone in a 67-year-old woman is described. The primary tumor originated the superficial lobe right parotid gland, and was treated with surgery 10 times over 30 years, followed by radiotherapy 50 Gy. secondary appeared 32 months after bone, extending to posterior cranial f ossa foramen magnum. Right partial resection lateral suboccipital craniotomy were performed on this metastasizing adenoma. Metastasizing very unusual tumor, which appears...

10.5106/jjshns.13.41 article EN JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY 2003-01-01
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