- Refrigeration and Air Conditioning Technologies
- Heat Transfer and Optimization
- Adsorption and Cooling Systems
- Meningioma and schwannoma management
- Heat Transfer and Boiling Studies
- Head and Neck Surgical Oncology
- Building Energy and Comfort Optimization
- Thermodynamic and Exergetic Analyses of Power and Cooling Systems
- Engineering Applied Research
- Energy and Environmental Systems
- Pituitary Gland Disorders and Treatments
- Advanced Thermodynamics and Statistical Mechanics
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Bladder and Urothelial Cancer Treatments
- Cerebrospinal fluid and hydrocephalus
- Neurosurgical Procedures and Complications
- Thermal Radiation and Cooling Technologies
- Traumatic Brain Injury and Neurovascular Disturbances
- Solar Thermal and Photovoltaic Systems
- Fluid Dynamics and Thin Films
- Oral and Maxillofacial Pathology
- Bone Tumor Diagnosis and Treatments
Waseda University
2016-2025
Fukushima Medical University
2015-2024
Niigata University
2014-2024
Japan Organization of Occupational Health and Safety
2023
Fukushima Medical University Hospital
2022
University of Yamanashi
2022
Central Research Institute of Electric Power Industry
2000-2021
Utsunomiya University
2019
Tokushima Red Cross Hospital
2018
Nagoya University
2001-2016
Utilizing 125I-BSA administered intravenously, a simple, reliable, and sensitive method was established for the detection of plasma protein extravasation in dura rats guinea pigs following chemical, electrical, or immunological stimulation. Extravasated Evans blue noted conjunctiva but not temporalis muscle saline-perfused intravenous capsaicin, 1 mumol/kg. Capsaicin-induced mediated by unmyelinated small myelinated fibers since leakage did develop adult animals whom these were destroyed...
Abstract Although the ergot alkaloids (ergots) are useful drugs for acute treatment of migraine headaches, their mechanism action remains obscure. When administered to rats in clinically relevant doses, ergots blocked development neurogenic plasma extravasation dura mater. Plasma was induced by depolarization perivascular axons following capsaicin injection or unilateral electrical stimulation trigeminal nerve. The could not be accounted vasoconstriction alone because leakage angiotensin...
Meningiomas are among the most common intracranial tumors and mostly curable by surgical resection. However, some populations of meningiomas with benign histological profiles show malignant behavior. The reasons for this inconsistency yet to be ascertained, novel diagnostic criteria other than one urgently needed. aim present study is subclassify from viewpoint gene methylation determine subgroup characteristics. Thirty were analyzed using microarrays 6157 genes classified into three...
We studied clinical features and pathologic findings in 52 consecutively autopsied patients with multiple myeloma our center between 1979 1998. Distant extraosseous involvement was found 33 (63.5%). Thirty-one (59.6%) were proven to have infection at autopsy, among which pneumonia most common site of infection. Amyloidosis shown 8 patients. Second malignancies observed 4 cases. The three major causes death hemorrhage, infection, renal failure, accounted for approximately 70% the Advances...
The effect of human adrenomedullin on cerebral circulation was investigated in dogs vivo and vitro. Bolus administration or its homologous peptides, calcitonin gene-related peptide (CGRP) amylin, into the vertebral artery induced a dose-dependent increase blood flow. potencies CGRP were similar approximately 100 times more than that amylin. effects inhibited by 8-37 , an antagonist CGRP. In contrast to substance P, did not induce flow after prior Pretreatment with either N G...
The intravenous infusion of rat adrenomedullin, at concentrations ranging from 0.1 to 1.0 microgram/kg/min, for 60 min increased the regional cerebral blood flow (rCBF) in a dose-dependent manner rats. rCBF was measured using laser Doppler flowmetry device placed on surface parietal cortex. increase induced by microgram/kg/min adrenomedullin up 145 +/- 10.8% controls (n = 5, p < 0.001). These did not affect systemic pressure or other physiologic parameters, including pH, PaCO2, PaO2,...
THE SURGICAL TREATMENT of large pituitary adenomas with suprasellar extensions has been controversial. To elucidate the indications for transsphenoidal surgery and to evaluate techniques removing portions tumors, surgical procedures on 100 consecutive patients nonfunctioning were retrospectively investigated. Patients followed up 1 12 years (mean, 4.5 yr). One hundred twenty-five operations performed patients. The removal each tumor was facilitated by placement a lumbar subarachnoid catheter...
The authors describe the use of a bifrontal basal interhemispheric approach with or without division anterior communicating artery (ACoA) for removal large craniopharyngiomas. This is more modification approach; allowing preservation most bridging veins. Since 1988, 22 patients underwent operations using this to achieve total near-total excision Division ACoA was performed in 11 17 retrochiasmatic tumors no early late complications related artery. There were operative mortalities. Visual...