Mariaelena D’Ambrosio

ORCID: 0000-0001-8802-0943
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About
Contact & Profiles
Research Areas
  • Marine Invertebrate Physiology and Ecology
  • Environmental Toxicology and Ecotoxicology
  • Marine Toxins and Detection Methods
  • Marine Sponges and Natural Products
  • Venomous Animal Envenomation and Studies
  • Mercury impact and mitigation studies
  • Nicotinic Acetylcholine Receptors Study
  • Heavy metals in environment
  • Photodynamic Therapy Research Studies
  • Microplastics and Plastic Pollution
  • Porphyrin Metabolism and Disorders
  • Parasite Biology and Host Interactions
  • Insect and Pesticide Research
  • Marine and coastal ecosystems
  • Ion channel regulation and function
  • Heme Oxygenase-1 and Carbon Monoxide
  • Marine Ecology and Invasive Species
  • Porphyrin and Phthalocyanine Chemistry
  • Pesticide Exposure and Toxicity

Universidade Nova de Lisboa
2020-2024

University of Lisbon
2021-2024

University of Coimbra
2013-2018

Institute of Marine Research
2013

The current study investigates the venom-delivery system of green and red morphotypes sea anemone Actinia equina to disclose its potential as a source bioactive compounds. We compared two using electron optical microscopy, proteomics, toxicity assessment on zebrafish embryos. Specialized venom-injecting cells (nematocysts) are equally distributed found in tentacles both varieties. Proteomics revealed proteins interest Actinia, yielding three most abundant Gene Ontology (GO) terms related...

10.3390/ani14060981 article EN cc-by Animals 2024-03-21

The present study investigated the potential toxicity of venomous secretions two polychaetes, Hediste diversicolor and Glycera alba (Annelida: Phyllodocida). Toxic activity putative toxins, measured on mussel gills through Comet assay, revealed higher effects caused by extracts from H. skin G. specialised, jawed proboscis, when compared to control. results suggest that secretes toxins via for protection against predators, contrarily alba, who predation.

10.1016/j.toxcx.2022.100116 article EN cc-by-nc-nd Toxicon X 2022-03-10

Porphyrins and derivatives form one of the most abundant classes biochromes. They result from breakdown heme have crucial physiological functions. Bilins are well-known representatives this group that, besides significant antioxidant anti-mutagenic properties, also photosensitizers for photodynamic therapies. Recently, we demonstrated that Polychaeta Eulalia viridis, common in Portuguese rocky intertidal, holds a high variety novel greenish yellowish porphyrinoid pigments, stored as granules...

10.3390/md18060302 article EN cc-by Marine Drugs 2020-06-06

The immense biodiversity of marine invertebrates makes them high-value targets for the prospecting novel bioactives. present study investigated proteinaceous toxins secreted by skin and proboscis Glycera alba (Annelida: Polychaeta), whose congenerics G. tridactyla dibranchiata are known to be venomous. Proteomics bioinformatics enabled detection bioactive proteins that hold potential biotechnological applications, including like glycerotoxins (GLTx), which can interfere with neuromuscular...

10.3390/toxins15110655 article EN cc-by Toxins 2023-11-14

The past decade has seen growing interest in marine natural pigments for biotechnological applications. One of the most abundant classes biological is tetrapyrroles, which are prized targets due their photodynamic properties; porphyrins best known examples this group. Many animal porphyrinoids and other tetrapyrroles produced through heme metabolic pathways, bile biliverdin bilirubin. Eulalia a Polychaeta characterized by its bright green coloration resulting from remarkably wide range...

10.3390/molecules26133924 article EN cc-by Molecules 2021-06-27

Marine biodiversity has been yielding promising novel bioproducts from venomous animals. Despite the auspices of conotoxins, which originated paradigmatic painkiller Prialt, biotechnological potential gastropod venoms remains to be explored. bioprospecting is expanding towards temperate species like dogwhelk Nucella lapillus, suspected secrete immobilizing agents through its salivary glands with a relaxing effect on musculature preferential prey, Mytilus sp. This work focused detecting,...

10.3390/md19050276 article EN cc-by Marine Drugs 2021-05-15

Event Abstract Back to Drivers of interannual abundance changes in gelatinous carnivore zooplankton the Iberian Peninsula, (Portugal) Sónia C. Marques1, 2, 3*, Mariaelena D'Ambrosio4, Ana L. Primo2, Juan-Carlos Molinero5 and Miguel Â. Pardal2 1 Center for Marine Environmental Sciences (MARE), Portugal 2 Functional Ecology, University Coimbra, 3 Portuguese Institute Ocean Atmosphere (IPMA), 4 SeaTox Lab, Faculty Technology, New Lisbon, 5 UMR9190 Centre pour la biodiversité marine,...

10.3389/conf.fmars.2019.08.00187 article EN cc-by Frontiers in Marine Science 2019-01-01
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