Hui Yan

ORCID: 0000-0001-8810-0193
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About
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Research Areas
  • Virus-based gene therapy research
  • Herpesvirus Infections and Treatments
  • Platelet Disorders and Treatments
  • Lung Cancer Treatments and Mutations
  • Dietary Effects on Health
  • MicroRNA in disease regulation
  • Blood Coagulation and Thrombosis Mechanisms
  • Antimicrobial Peptides and Activities
  • Blood disorders and treatments
  • Plant tissue culture and regeneration
  • Cancer Research and Treatments
  • Clinical Nutrition and Gastroenterology
  • Hematopoietic Stem Cell Transplantation
  • Renal and related cancers
  • Toxin Mechanisms and Immunotoxins
  • Cancer Genomics and Diagnostics
  • Enhanced Recovery After Surgery
  • Transgenic Plants and Applications
  • Aquaculture disease management and microbiota
  • Venomous Animal Envenomation and Studies
  • Circular RNAs in diseases
  • Immunotherapy and Immune Responses
  • Genetic factors in colorectal cancer

Nanjing Drum Tower Hospital
2024

Huaqiao University
2023

Chifeng Municipal Hospital
2021

Tongji Hospital
2020

Zhejiang Academy of Medical Sciences
2008-2020

Huazhong University of Science and Technology
2020

Hangzhou Normal University
2020

Chinese Academy of Fishery Sciences
2015

Xijing Hospital
2003

Air Force Medical University
2003

Platelet transfusion is important in the prevention and treatment of bleeding patients with acute myeloid leukemia (AML) after receiving intensive chemotherapy. However, platelet refractoriness (PTR) an intractable clinical issue occurred these patients. And its immunological features remain largely unknown. The potential causes PTR were retrospectively analyzed 560 who diagnosed as de novo AML Tongji Hospital from June 2012 through 2018. A high-throughput antibody screening for detection...

10.1002/cam4.3140 article EN cc-by Cancer Medicine 2020-05-18

Cancer is still a leading of cause death worldwide. Among the bio-therapy strategies for cancer, vaccinia virus (VV) has been widely used as an expression vector because its potent oncolytic activities in addition to large capacity insertion foreign genes and excellent safety records. In present study, novel recombinant VV, VV-HBD2-lac

10.1016/j.omto.2019.03.010 article EN cc-by-nc-nd Molecular Therapy — Oncolytics 2019-04-04

Anti-tumor vaccines have been shown to be effective in cancer therapeutics ever since the anti-HPV vaccine was developed. Compared conventional chemotherapy, anti-tumor can specifically target cells and they lower side effects. We developed a recombinant vaccinia virus (VACV) (Western Reserve) WR strain, we tested its effects an animal model.A VACV strain expressing mutant survivin T34A (SurT34A) FilC constructed validated. Its oncolytic effect vitro using CCK-8 assay, tolerance were murine...

10.2147/ott.s230902 article EN OncoTargets and Therapy 2020-02-01

Thrombosis has been emerging as a major global life-threatening issue with high mortality and serious complications, especially in the post-COVID-19 era. Compared commonly used plasminogen activators thrombolytic drugs, fibrinolytic drugs are no longer heavily dependent on patients’ own plasminogen, which poorly expressed most patients. As novel “direct acting” agent, considered to have stronger efficacy safety than widely activators. However, risk of their hemorrhage remains concern....

10.1097/mbc.0000000000001231 article EN Blood Coagulation & Fibrinolysis 2023-06-07

The incidence of enteral feeding intolerance (ENFI) in the early postoperative period is high patients after gastric cancer resection due to characteristics surgical traumatic stress and changes physiological structure digestive tract, current evaluation ENFI mostly depends on symptoms complaints resection, which lagging subjective. Early accurate objective prediction risk critical guide clinical nutrition practice.

10.3389/fnut.2024.1480390 article EN cc-by Frontiers in Nutrition 2024-11-26
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