A5025909748- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastric Cancer Management and Outcomes
- Ocular Diseases and Behçet’s Syndrome
- Anesthesia and Sedative Agents
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Mycobacterium research and diagnosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Treatments and Studies
- Nausea and vomiting management
- Autoimmune and Inflammatory Disorders
- Helicobacter pylori-related gastroenterology studies
- Liver Disease and Transplantation
- Gastrointestinal Tumor Research and Treatment
- Intensive Care Unit Cognitive Disorders
- Genetic factors in colorectal cancer
- Colorectal Cancer Surgical Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Metastasis and carcinoma case studies
- Liver Diseases and Immunity
- Cancer Cells and Metastasis
- Eosinophilic Esophagitis
- Cytomegalovirus and herpesvirus research
- Vasculitis and related conditions
Ewha Womans University
2021-2025
Yonsei University
2014-2024
Ewha Womans University Medical Center
2023-2024
Severance Hospital
2018
Kyungpook National University Hospital
2008-2009
Controlled attenuation parameter (CAP) is a non-invasive method of measuring hepatic steatosis using process based on transient elastography. We investigated the diagnostic accuracy CAP in detecting patients with chronic liver disease (CLD).A total 135 CLD who underwent biopsy and were consecutively enrolled this prospective study. The performance for detection compared was calculated area under receiver operating characteristics curves (AUROC). Steatosis categorized into S0 (<5%), S1...
The hepatoma arterial-embolization prognostic (HAP) score predicts survival outcome in patients with hepatocellular carcinoma (HCC) treated trans-arterial chemoembolization (TACE). We validated the HAP Korean subjects HCC and investigated whether its performance is improved additional parameters.A total of 280 TACE between 2003 2009 were included. Validation modification performed based on multivariate Cox regression models.The median age study population (211 men, 69 women) was 60 years....
See also: Commentaire de travail D. Park et al., pp. 7Endoscopy 2008; 40(01): 88-89DOI: 10.1055/s-0032-1306799
AIMTo assess factors associated with the higher effect of metformin on mortality in diabetic colorectal cancer (CRC) patients, since related to effectiveness have not been identified yet.
Background & Aims Few noninvasive methods can accurately identify esophageal varices (EVs) in patients with compensated cirrhosis. We developed and validated a novel, acoustic radiation force impulse (ARFI) elastography-based prediction model for high-risk EVs (HEVs) Methods A total of 143 cirrhosis between February, 2010 2013 (training set) 148 June, May, (validation who underwent ARFI elastography endoscopy were prospectively recruited. Independent predictors HEVs used to construct model....
The diagnostic and prognostic values of fecal calprotectin (FC) levels in patients with inflammatory bowel diseases have been proven. However, little is known about the usefulness FC measurement predicting intestinal involvement Behçet's disease (BD).Forty-four consecutive systemic BD who underwent colonoscopy for evaluation gastrointestinal symptoms were prospectively enrolled between November 2012 March 2014 a single tertiary medical center. Fecal specimens from obtained day before...
Introduction: Periodontitis and other oral health indicators are reportedly related to systemic inflammation. Our study aimed investigate a possible association of status (periodontitis number missing teeth) hygiene behaviors (frequency tooth brushing, dental visit, scaling) with the risk inflammatory bowel disease (IBD) incidence. Methods: Utilizing Korean National Health Insurance Database, we conducted nationwide, population-based cohort involving participants from 2003 national screening...
Abstract Background The patients with ulcerative colitis (UC) can have low quality of life and their work productivity be also impaired. aim this study is to investigate the activity impairment (WPAI) moderate severe UC biologics treatment, using MOSAIK cohort (ClinicalTrials.gov: NCT02229344). Methods In cohort, we enrolled diagnosed for first time collected WPAI questionnaires annually from diagnosis. scored overall social 0 10. We compared scores between treated without biologics. Results...
Abstract Background Inflammatory bowel disease (IBD), including Crohn’s (CD) and ulcerative colitis (UC), is a chronic condition marked by intestinal inflammation. IBD diagnosed in children tends to more extensive involvement, but generally responds well treatment than adult-onset cases. This study aims compare the long-term clinical characteristics, patterns, prognosis of patients before after age 18. Methods A retrospective was conducted using data from 352 with duration exceeding 10 years...
Abstract Background The Mesentery, initially considered as a structure support of abdominal organs, has emerged an active participant in the inflammatory processes Crohn's disease (CD). It serves central hub for immune cell activity, including macrophages, T cells, and B driving propagation inflammation. Additionally, mesenteric fibroblasts play crucial role CD-associated fibrosis. These are activated by pro-fibrotic cytokines such TGF-β IL-13, leading to excessive extracellular matrix (ECM)...
Self-expandable metallic stents (SEMSs) are widely used as palliative or bridge to surgery treatments in patients with malignant colorectal obstruction (MCO). Stent occlusion is more common uncovered stents, but stent migration covered stents. Our purpose was compare the efficacy and safety of a newly designed SEMS an proximal flared end (CSEMS-UPF) that conventional (UCSEMS) treatment MCO. This prospective randomized trial conducted at tertiary-care academic hospital. We enrolled 87 stage 4...
The MiroCam MC2000 (MC2000) is a double-tip capsule with camera on each side. It designed to provide more extensive visualization of the small bowel mucosa, potentially reducing chance missing lesions. This study aimed compare detection rates for lesions in ampulla Vater (AoV) and PillCam SB3 (SB3) patients suspected bleeding. prospective, multicenter, randomized crossover trial compared lesion capabilities capsules, ingested one hour apart by primary outcome was AoV, while secondary...
The aim of this study was to identify the effect mucosal healing (MH) on clinical relapse in patients with ulcerative colitis (UC) who are remission, special reference Mayo endoscopic subscore 0.Between November 2005 and December 2013, medical records from a total 215 UC underwent colonoscopic examination at time remission were retrospectively reviewed. Endoscopic MH defined as '0 point' (Mayo 0). Patients categorized into two groups according then analyzed.The baseline characteristics both...
A considerable number of patients with Crohn's disease (CD) develop irreversible intestinal damage, although the early administration immunomodulatory or biological therapies might prevent this. The aims our study were to and validate a novel predictive model that can be used predict risk surgical intervention in Korean CD. prognostic was derived from multicenter longitudinal CONNECT (CrOhn's cliNical NEtwork CohorT) cohort consisting 1338 CD, who split into training validation sets. Disease...
Monitoring fibrosis is mandatory for detailed prognostification in patients with chronic liver disease. We developed optimized cut-offs stiffness (LS) values, based on the histological subclassification of cirrhosis, and investigated whether early on-treatment changes LS values can predict long-term prognosis hepatitis B virus (HBV)-related advanced receiving antiviral therapy.Between 2005 2008, 103 F3 or F4 biopsy were enrolled prospectively. Cirrhosis was subclassified into three groups...
BACKGROUND: Metformin may reduce cancer risk and mortality improve radiotherapy responses in several malignancies. OBJECTIVE: This study aimed to compare tumor prognoses of metformin nonmetformin groups diabetic patients receiving neoadjuvant concurrent chemoradiotherapy for rectal cancer. DESIGN: is a retrospective study. SETTING: was conducted at single institution the Republic Korea. PATIENTS: Between January 2000 November 2017, 104 with who were taking diabetes medication treated...
Nutritional support has become an important intervention for critically ill patients. Many studies have reported on the effects of nutritional patients within intensive care unit (ICU); however, no specifically assessed with gastrointestinal diseases who may difficulty absorbing enteral nutrition (EN) in ICU. Sixty-two disease were admitted to ICU between August 2014 and 2016 at a single tertiary university hospital. We analyzed 2 different patient groups retrospective cohort study: those...