A5047135813- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Liver physiology and pathology
- Drug Transport and Resistance Mechanisms
- Amino Acid Enzymes and Metabolism
- Enhanced Recovery After Surgery
- Neuroendocrine Tumor Research Advances
- Renal Transplantation Outcomes and Treatments
- Neonatal Health and Biochemistry
- Colorectal and Anal Carcinomas
- HIV/AIDS drug development and treatment
- Nutrition and Health in Aging
- Renal cell carcinoma treatment
- Hydrogen's biological and therapeutic effects
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Organ Transplantation Techniques and Outcomes
- Colorectal Cancer Surgical Treatments
- Cancer Cells and Metastasis
- Transplantation: Methods and Outcomes
Huazhong University of Science and Technology
2016-2020
Union Hospital
2016-2017
Union Hospital
2011-2016
Central South University
2006-2010
Third Xiangya Hospital
2006-2010
Background and Objective A prospective study was conducted to investigate the effect of anterior approach for hepatectomy on long-term outcome HCC patients with different tumor size. Methods Long-term outcomes were investigated between size underwent liver resection by either or conventional (i.e., AA CA group). Results The recurrence rate in group much lower than that (52.4% vs.73.1%, P = 0.001). survival higher (60.0% vs. 38.0%, < Furthermore, differences rates large-size (>5 cm) groups...
Abstract Background The predictive model of postsurgical recurrence for solitary early hepatocellular carcinoma (SE-HCC) is not well established. aim this study was to develop a novel prediction and survival patients with hepatitis B virus (HBV)-related SE-HCC ≤10 cm. Patients Methods Data from 1,081 HBV-related cm who underwent curative liver resection 2003 2016 in our center were collected retrospectively randomly divided into the derivation cohort (n = 811) internal validation 270). Eight...
Introduction To evaluate the impact of intermittent portal clamping (IPC) on long-term postoperative outcomes in patients with hepatocellular carcinoma (HCC). Methods Clinical records 355 underwent curative liver resection for HCC January 2007 to December 2010 were retrospectively reviewed. According how was performed, grouped as: IPC, n=113; other (OPC), n=190; and no (NPC), n=52. Results Median recurrence-free survival (RFS) statistically significantly shorter IPC (39.4 months) than OPC...
Objective To investigate the influence of MDR polymorphism on CsA-associated hepatotoxicity. Methods PCR/RFLP was used to analyze genotypes exon26 in 187 recipients. hepatotoxicity evaluated among groups being classified according genotypes. Results takes 3 genotypes:CC,CT and TT, following ratio: 29.4%(55/187), 40.1%(75/187), 30. 5%(57/187). Among same range whole blood CsA concentration, incidence is markedly higher CT/TT group than that patients with between CC signifiimportant role...
Objective To investigate the influence of donor MDR polymorphism on acute CsA-associated nephrotoxicity.Methods By using PCR/REFP, exon26 genotypes were analyzed among donors (n=116) and recipients (n=173).All patients grouped according to donor's respectively.The in each group followed up with serum creatine, BUN 24 h urine amount within 3 months postoperatively.Results Exon26 CC, CT, TT recipients, ratio as follows: 28.3% (49/173), 41.6 % (72/173) 30.0 (52/173) donors; 28.4 (33/116), 41.3...
Objective To evaluate the iminunosuppressive efficacy of Tacrolimus under context alteration lymphocytes P-gp expression in transplant recipients. Methods According to level healthy adults (14.5% ) ,78 recipients were classified into high (>20% and low (<20% groups. Using lymphocyte culture experimental system, we analyzed influence on suppress proliferation IL-2 secretion by PHA stimulation. Results Under concentration between (5-10) μg/L medium, almost suppressed control (25% ,10 ng/L)...