A5101759230- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Pancreatic function and diabetes
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Organ Transplantation Techniques and Outcomes
- Cancer-related gene regulation
- Pancreatitis Pathology and Treatment
- Epigenetics and DNA Methylation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Abdominal vascular conditions and treatments
- Liver physiology and pathology
- Cerebral Palsy and Movement Disorders
- Apelin-related biomedical research
- Cancer Mechanisms and Therapy
- Abdominal Surgery and Complications
- Adenosine and Purinergic Signaling
- Photodynamic Therapy Research Studies
- Cardiac Ischemia and Reperfusion
- Cannabis and Cannabinoid Research
- Biliary and Gastrointestinal Fistulas
- Pickering emulsions and particle stabilization
- Multiple Sclerosis Research Studies
- Abdominal Trauma and Injuries
- Advanced Materials and Mechanics
Union Hospital
2012-2025
Huazhong University of Science and Technology
2012-2025
Chinese University of Hong Kong
2025
Ruijin Hospital
2022
Shanghai Jiao Tong University
2022
Zhejiang University
2022
Tianjin Medical University General Hospital
2019
Union Hospital
2014-2016
Hong Kong Polytechnic University
2016
Wuhan Union Hospital
2005
Cerebral aneurysms and brain tumors are leading life-threatening diseases worldwide. By deliberately occluding the target lesion to reduce blood supply, embolization has been widely used clinically treat cerebral tumors. Conventional is usually performed by threading a catheter through vessels lesion, which often limited poor steerability of in complex neurovascular networks, especially submillimeter regions. Here, we propose magnetic soft microfiberbots with high steerability, reliable...
Protein arginine methyltransferase 5 (PRMT5) plays multiple roles in a large number of cellular processes, and its subcellular localization is dynamically regulated during mouse development differentiation. However, little known the functional differences between PRMT5 cytoplasm nucleus. Here, we demonstrated that predominantly localized prostate cancer cells. Subcellular assays designed to span entire open-reading frame protein revealed presence three nuclear exclusion signals (NESs)...
The NSD family of histone lysine methyltransferases have emerged as important biomarkers that participate in a variety malignancies. Recent evidence has indicated somatic dysregulation the nuclear receptor binding SET domain-containing protein 1 (NSD1) is associated with tumorigenesis HCC, suggesting NSD1 may serve prognostic target for this malignant tumor. However, its mechanism human hepatocellular carcinoma (HCC), major primary tumor liver, remains unclear. Hence, we investigated how...
This research focused on exploring the association between coagulopathy scores and survival outcomes, both short-term long-term, in individuals diagnosed with liver cirrhosis complicated by sepsis. study retrospectively analyzed data from sepsis who were admitted to intensive care unit (ICU) at Beth Israel Deaconess Medical Center 2008 2022. The main outcome of interest was all-cause mortality within 28 days post-admission, while secondary assessed 90 days. We used Kaplan-Meier analysis...
Photodynamic therapy (PDT) has emerged as a promising locoregional of hepatocellular carcinoma (HCC). The utilization luminogens with aggregation-induced emission (AIE) characteristics provides new opportunity to design functional photosensitizers (PS). PSs targeting the critical organelles that are susceptible reactive oxygen species damage is strategy enhance effectiveness PDT. In this paper, PS, 1-[2-hydroxyethyl]-4-[4-(1,2,2-triphenylvinyl)styryl]pyridinium bromide (TPE-Py-OH)...
Islet transplantation may potentially cure type 1 diabetes mellitus (T1DM). However, immune rejection, especially that induced by the alloreactive T-cell response, remains a restraining factor for long-term survival of grafted islets. Programmed death ligand-1 (PD-L1) is negative costimulatory molecule. PD-L1 deficiency within donor heart accelerates allograft rejection. Here, we investigate whether in islets reduces time.Glucose Stimulation Assays were performed to evaluate has detrimental...
Background and Objective A prospective study was conducted to investigate the effect of anterior approach for hepatectomy on long-term outcome HCC patients with different tumor size. Methods Long-term outcomes were investigated between size underwent liver resection by either or conventional (i.e., AA CA group). Results The recurrence rate in group much lower than that (52.4% vs.73.1%, P = 0.001). survival higher (60.0% vs. 38.0%, < Furthermore, differences rates large-size (>5 cm) groups...
Introduction To evaluate the impact of intermittent portal clamping (IPC) on long-term postoperative outcomes in patients with hepatocellular carcinoma (HCC). Methods Clinical records 355 underwent curative liver resection for HCC January 2007 to December 2010 were retrospectively reviewed. According how was performed, grouped as: IPC, n=113; other (OPC), n=190; and no (NPC), n=52. Results Median recurrence-free survival (RFS) statistically significantly shorter IPC (39.4 months) than OPC...
Abstract Background This study aimed to compare postoperative complications in patients with esophagogastric variceal bleeding (EVB) who underwent laparoscopic splenectomy combined pericardial devascularization (LSPD) versus transjugular intrahepatic portosystemic shunt (TIPS) procedures. Methods A retrospective collection of medical records was conducted from January 2014 May 2020 at Union Hospital, Tongji Medical College, Huazhong University Science and Technology. The included the...
Laparoscopic hepatectomy has been performed in many hospitals, with the development of laparoscopic operation technique. However, performing complex hepatectomy, such as right hemihepatectomy, is still a challenge. The aim this study was to describe application simple vascular occlusion technique and new liver hanging maneuver (LHM) which are both advocated by Chen Xiaoping for open hepatectomy.The clinical data 29 consecutive patients who underwent hemihepatectomy (LRH) from October 2014...
The aim of this study is to investigate the effects multidisciplinary rehabilitation for patients with neuromyelitis optica spectrum disorders who have moderate severe disability.In 39 disorders, disability was assessed after 4 weeks and 3 months follow-up.In underwent rehabilitation, bowel bladder motor functions (pyramidal walking function) were improved compared those usual care.These results confirm shortterm effectiveness in terms improving impairment.The also suggest that a safe...
The prevalence of peripheral arterial disease (PAD) is on the rise globally, leading to adverse clinical outcomes. Our aim was investigate causal relationship between apolipoprotein and PAD, as well potential mediating role smoking, diabetes, hypertension, myocardial infarction, ischemic stroke.