A5072404388- Cancer survivorship and care
- BRCA gene mutations in cancer
- Family Support in Illness
- Childhood Cancer Survivors' Quality of Life
- Cancer-related cognitive impairment studies
- Stress Responses and Cortisol
- Nausea and vomiting management
- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- Pain Management and Placebo Effect
- Cancer, Stress, Anesthesia, and Immune Response
- Complementary and Alternative Medicine Studies
- Breast Cancer Treatment Studies
- Smoking Behavior and Cessation
- Pain Management and Opioid Use
- Tryptophan and brain disorders
- Sleep and related disorders
- Health, psychology, and well-being
- Nicotinic Acetylcholine Receptors Study
- Music Therapy and Health
- Posttraumatic Stress Disorder Research
- Cancer Genomics and Diagnostics
- Anesthesia and Pain Management
- Estrogen and related hormone effects
- Optimism, Hope, and Well-being
UPMC Hillman Cancer Center
2015-2024
University of Pittsburgh Medical Center
2009-2023
University of Pittsburgh
2013-2022
Roughan & O'Donovan Innovative Solutions
2022
Campbell Collaboration
2022
Magee-Womens Hospital
2019
American Cancer Society
2015
The University of Texas at San Antonio
2015
Icahn School of Medicine at Mount Sinai
2002-2014
Babeș-Bolyai University
2007-2014
Breast cancer surgery is associated with side effects, including postsurgical pain, nausea, and fatigue. We carried out a randomized clinical trial to test the hypotheses that brief presurgery hypnosis intervention would decrease intraoperative anesthesia analgesic use effects breast it be cost effective. randomly assigned 200 patients who were scheduled undergo excisional biopsy or lumpectomy (mean age 48.5 years) 15-minute session conducted by psychologist nondirective empathic listening...
Hypnosis is a nonpharmacologic means for managing adverse surgical side effects. Typically, reviews of the hypnosis literature have been narrative in nature, focused on specific outcome domains (e.g., patients' self-reported pain), and rarely address impact different modes administration. Therefore, it important to take quantitative approach assessing beneficial adjunctive patients, as well examine whether goes beyond pain method We conducted meta-analyses published controlled studies (n =...
Persistent postmastectomy pain (PPMP) is a major individual and public health problem. Increasingly, psychosocial factors such as anxiety catastrophizing are being revealed crucial contributors to differences in processing outcomes. Furthermore, patients' responses standardized quantitative sensory testing (QST) may aid the discernment of who at risk for acute chronic after surgery. However, characterization variables that differentiate those with PPMP from whose postoperative resolves...
The objective of this study was to test the efficacy cognitive-behavioral therapy plus hypnosis (CBTH) control fatigue in patients with breast cancer undergoing radiotherapy. We hypothesized that CBTH group receiving radiotherapy would have lower levels than an attention group.Patients (n = 200) were randomly assigned either 100; mean age, 55.59 years) or 55.97 group. Fatigue measured at four time points (baseline, end radiotherapy, 4 weeks, and 6 months after radiotherapy). using Functional...
Postoperative ambulation is encouraged to promote timely recovery but rarely monitored objectively or examined as a predictor of clinical outcomes, despite growing availability wearable devices that allow passive quantification and remote real-time monitoring the number steps taken during recovery. To determine whether inpatient predicts 30- 60-day readmission risk after metastatic cancer surgery. Patients diagnosed with peritoneal scheduled for surgical resection were enrolled in this...
Abstract Each year, hundreds of thousands women undergo excisional breast biopsies for definitive diagnosis. Not only do these patients experience pain associated with the procedure, but they also endure distress threat cancer. Hypnosis has been demonstrated as effective controlling patients' in other surgical settings, surgery have received little attention. To determine impact brief presurgical hypnosis on postsurgery and to explore possible mediating mechanisms effects, 20 biopsy were...
Abstract Previous studies of rhinovirus infection indicate that about one third the persons with confirmed viral do not show evidence cold symptoms. Factors determine which infected individuals will develop colds are known. Using a inoculation protocol, authors explored possible role recent life events, current mood, and perceived stress in development symptoms known to be infected. As part larger study, 17 subjects were exposed individually isolated for 5 consecutive days; symptoms, mucus...
Having a family history of cancer is an important predictor lifetime risk. Individuals with histories have been reported to experience symptoms general distress and frequent intrusive thoughts avoidance regarding cancer. To date, little known about predictors such distress. A relation between perception risk has suggested, but the possibility that prior cancer-related events may contribute in these women received attention. The major aim study was examine contribution past death parent from...
Prior to scheduled surgery, patients frequently experience particularly high levels of distress and expect a variety postsurgery symptoms. Surgery who confront breast cancer are no exception. It has been suggested that such presurgery response expectancies predictive outcomes. To test the contribution common symptom outcomes (pain, nausea, fatigue, discomfort), 63 female undergoing surgery were recruited prospective study. Results indicated uniquely contributed patients' discomfort; specific...
Breast cancer in African-American (AA) women occurs at an earlier age than European-American (EA) and is more likely to have aggressive features associated with poorer prognosis, such as high-grade negative estrogen receptor (ER) status. The mechanisms underlying these differences are unknown. To address this, we conducted a case-control study evaluate risk factors for ER- disease both AA EA women. With the onset of Health Insurance Portability Accountability Act 1996, creative measures were...
The study purpose was to test the effectiveness of a psychological intervention combining cognitive-behavioral therapy and hypnosis (CBTH) treat radiotherapy-related fatigue.Women (n = 42) scheduled for breast cancer radiotherapy were randomly assigned receive standard medical care (SMC) 20) or CBTH 22) in addition SMC. Participants met individually with clinical psychologist. participants received training CBT. SMC control condition did not meet psychologist.Fatigue measured on weekly basis...
The present study was designed to test the hypotheses that response expectancies and emotional distress mediate effects of an empirically validated presurgical hypnosis intervention on postsurgical side (i.e., pain, nausea, fatigue).Women (n = 200) undergoing breast-conserving surgery (mean age 48.50 years; 63% White, 15% Hispanic, 13% African American, 9% other) were randomized a or attention control group. Prior surgery, patients completed assessments hypothesized mediators (response...
An illness-induced taste aversion was conditioned in mice by pairing cyclophosphamide, an immunosuppressive drug, with the consumption of saccharin, a novel drinking solution. Two weeks after conditioning, animals were injected hapten trinitrophenyl (TNP) coupled to thymus-independent carrier, lipopolysaccharide. Serum antibodies TNP titered 6 days later passive hemagglutination. Relative control groups, provided saccharin at time antigenic stimulation and, again, 3 showed significant...
The study of posttraumatic growth (PTG) has burgeoned over the last decade, particularly in area oncology. aims were to: (1) describe PTG patients with hepatobiliary carcinoma, (2) examine agreement between patient and caregiver measures PTG, (3) test associations other psychological factors clinically relevant outcomes.Two hundred two carcinoma completed a battery standardized questionnaires that measured depressive symptoms, optimism, expressed emotion, quality life (QOL). A subsample...
Little is known about the development of posttraumatic stress disorder (PTSD) over time among women diagnosed with breast cancer. This study examines changes in PTSD symptoms first 6 months after diagnosis and assesses racial/ethnic differences symptomatology time. We recruited newly cancer, stages I to III, from three sites United States. Three telephone interviews were conducted: baseline at 2 3 diagnosis, follow-up 4 second diagnosis. measured traumatic each interview using Impact Events...