A5045639222- Pesticide Residue Analysis and Safety
- Pluripotent Stem Cells Research
- Identification and Quantification in Food
- Insect and Pesticide Research
- Analytical Methods in Pharmaceuticals
- Renal and related cancers
- Tissue Engineering and Regenerative Medicine
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotics Pharmacokinetics and Efficacy
- Salmonella and Campylobacter epidemiology
- Bone Metabolism and Diseases
- MicroRNA in disease regulation
- Indoor Air Quality and Microbial Exposure
- Pharmacological Effects and Assays
- Analytical Chemistry and Chromatography
- Muscle Physiology and Disorders
- Health and Lifestyle Studies
- TGF-β signaling in diseases
- Environmental DNA in Biodiversity Studies
- Advanced Chemical Sensor Technologies
- Child Nutrition and Water Access
- Iron Metabolism and Disorders
- Inflammatory mediators and NSAID effects
- Bee Products Chemical Analysis
Salk Institute for Biological Studies
2020-2022
Altos Labs
2022
Universidad Católica San Antonio de Murcia
2011-2020
Universidad de Murcia
2016
Short-term, systemic expression of the Yamanaka reprogramming factors (Oct-3/4, Sox2, Klf4 and c-Myc [OSKM]) has been shown to rejuvenate aging cells promote tissue regeneration in vivo. However, mechanisms by which OSKM promotes are unknown. In this work, we focus on a specific demonstrate that local OSKM, specifically myofibers, induces activation muscle stem or satellite (SCs), accelerates young mice. contrast, expressing directly SCs does not improve regeneration. Mechanistically,...
Mammals have limited regenerative capacity, whereas some vertebrates, like fish and salamanders, are able to regenerate their organs efficiently. The regeneration in these species depends on cell dedifferentiation followed by proliferation. We generate a mouse model that enables the inducible expression of four Yamanaka factors (Oct-3/4, Sox2, Klf4, c-Myc, or 4F) specifically hepatocytes. Transient vivo 4F induces partial reprogramming adult hepatocytes progenitor state concomitantly...
Introducción: La quinua es un pseudocereal que contiene hidratos de carbono bajo índice glucémico, fibra alimentaria, proteínas alto valor biológico, fitoesteroles y ácidos grasos n-3 n-6 ha suscitado interés en la intervención nutricional prediabetes. Este estudio aleatorizado (2:1), controlado con placebo doble ciego evaluó los efectos sobre el masa corporal (IMC), hemoglobina glicada (HbA1c), glucemia basal (GB) grado saciedad plenitud pacientes prediabéticos. Material método: Se...