We retrospectively reviewed the clinical features and outcome of benign malignant eyelid tumors from 1995 to 2015 in a tertiary medical center. Among 4,521 histologically confirmed tumors, 4,294 (95.0%) were 227 (5.0%) tumors. The mean age at diagnosis was significantly higher patients with lid than those (72.5 55.4 years, resp., p < 0.001). most common intradermal nevus (21.1%), followed by seborrheic keratosis (12.6%) xanthelasma (11.2%). basal cell carcinomas (57.8%), sebaceous gland...

The mutations in the genes encoding subunits of complex I mitochondrial electron transport chain are most common cause Leber's hereditary optic neuropathy (LHON), a maternal disease characterized by retinal ganglion cell (RGC) degeneration. characteristics incomplete penetrance indicate that nuclear genetic and environmental factors also determine phenotypic expression LHON. Therefore, further understanding role mutant nicotinamide adenine dinucleotide dehydrogenase subunit proteins...

This retrospective study included 10 eyes of 9 patients diagnosed with microsporidial keratitis. All them were known to contract this disease after taking baths in hot springs. The was based on detecting microsporidia corneal scrapings using Gram stain and the modified Kinyoun's acid-fast stain. specimens from last six subjected PCR then sequencing. revealed that microorganism identified has a high similarity Vittaforma corneae. Repeated debridement epithelial lesions successfully eradicated...

Our purpose was to determine the association of cataract surgery with subsequent development dementia in older adults newly diagnosed cataract.By using data from Taiwan National Health Insurance Research Database (NHIRD), a population-based cohort study including 491 226 subjects aged 70 or first-time diagnosis coded 2000 2009 conducted. After matching patients receiving without for age, sex, index date, Charlson Comorbidity Index score, interval between first coding and hypertension...

<h3>Aims</h3> To compare the clinical features and treatment outcome between lacrimal plug-related canaliculitis primary canaliculitis. <h3>Methods</h3> Patients with 2007 2014 in a medical centre were collected. Charts reviewed for features, microbiological profiles, time lapse plug insertion symptom onset, type of outcomes. <h3>Results</h3> Of 76 eligible cases collected, 13 63 The most common presenting was discharge both groups (85% 79%, respectively). average interval from to symptoms...

Diabetic macular edema (DME) is a sight-threatening condition that needs regular examinations and remedies. Optical coherence tomography (OCT) the most common used examination to evaluate structure thickness of macula, but software in OCT machine does not tell clinicians whether DME exists directly. Recently, artificial intelligence (AI) expected aid diagnosis generation therapy selection. We thus develop smartphone-based offline AI system provides diagnostic suggestions medical strategies...

The purpose of the study was to evaluate clinical features, treatment, and outcome patients with conjunctival papilloma.Twenty-two (22 eyes) biopsy-proven papilloma between January 2005 2015 in a tertiary medical center were retrospectively reviewed. Clinical profiles, outcome, factors related recurrence evaluated.There 16 males (73%) 6 females (27%), mean age 47 years. most common location caruncle (43%), followed by palpebral conjunctiva (29%), bulbar (14%), fornix (14%). Recurrence...

Orbital fibrosis, a hallmark of tissue remodeling in Graves’ ophthalmopathy (GO), is chronic, progressive orbitopathy with few effective treatments. fibroblasts are effector cells, and transforming growth factor β1 (TGF-β1) acts as critical inducer to promote myofibroblast differentiation subsequent fibrosis. Curcumin natural compound anti-fibrotic activity. This study aims investigate the effects curcumin on TGF-β1-induced pro-angiogenic activities orbital fibroblasts. from one healthy...

A 64-year-old male presented with progressive proptosis of the left eye for 3 months. Orbital computed tomography (CT) demonstrated a 3.9 cm infiltrative mass over superotemporal quadrant orbit. Pathology biopsy revealed ductal adenocarcinoma lacrimal gland positive immunohistochemical staining androgen receptor (AR), cytokeratin-7 (CK7), and gross cystic disease fluid protein 15 (GCDFP-15). The patient received orbital exenteration adjuvant chemoradiotherapy. No recurrence or metastasis was...

Purpose: To investigate the change of serum IgG4 concentrations correlated with clinical evolution in patients ocular adnexal marginal zone B cell lymphoma associated IgG4-related ophthalmic disease (IgG4-ROD). Methods: Three consecutive histopathologically confirmed IgG4-ROD were evaluated. Two received radiotherapy and 1 patient steroid therapy. Treatment outcome was evaluated by symptoms, radiologic examination, level these patients. Results: All had elevated before treatment (462, 338,...

We provided the first report of an association between changes in corneal endothelial cells, retina, and choriocapillaris a choroideremia family.Four members Asian family, comprising two affected patients carriers, were evaluated. All participants underwent complete eye examinations, including visual acuity (VA), slit-lamp examination, ophthalmoscopy, perimetry, electrophysiology tests. In addition, images endothelium captured with noncontact specular microscope. Genomic DNA amplification...

Purpose: Marin-Amat syndrome is an acquired facial synkinesis manifesting as involuntary eyelid closure on jaw movement. The authors investigate the clinical features, especially quantitative changes in parameters of patients with syndrome. Methods: Patients between 2015 and 2017 a medical center were collected. Clinical features change parameters, including margin reflex distance 1 (MRD-1), 2 (MRD-2), palpebral fissure height, evaluated. Results: There 5 men 3 women mean age 76 years. All...

Malignant melanoma can arise from melanocytes in various structures of the eye, orbit, and ocular adnexa. We reviewed clinical features long-term results all subjects with histologically proved originating any periocular a tertiary referral center. Overall, 88 patients including 47 men were recruited. The tumor was primarily located uvea, followed by conjunctiva, eyelid, lacrimal sac. Patients uveal diagnosed at relatively younger age (47.0 years), while those orbital eyelid melanomas older...

Abstract: Traumatic diplopia can be caused by an entrapped, ruptured, or lost extraocular muscle, which is clinically challenging. Numerous surgical approaches tailored, depending on muscle involved. We present a patient suffering from inferior rectus disruption treated with endoscopic transmaxillary approach and plication procedure. This technique novel effective in managing traumatic diplopia.

Clinical relevance Conjunctivitis, chalazion and blepharitis are routinely managed by optometrists. However, it is especially important to consider the diagnosis of canaliculitis in patients with chronic or recurrent conditions.Background This study aimed report clinical features, radiological findings treatment outcomes plug-related canaliculitis.Methods retrospective included secondary plug insertion between 2007 2020. All data regarding epidemiological characteristics, presentation,...

(1) Background: hydrogel scleral buckles (HSB)-related complications can happen decades after implantation, although this material has been retrieved for a long time. Due to its fragile texture, ensuring the complete removal of and avoiding are challenging. Incomplete removal, iatrogenic complication, recurrent retinal detachment, infection could occur. (2) Methods: chart review patients who developed delayed HSB-related received HSB in Taipei Veterans General Hospital from 2004 2021. The...

Purpose: To report the observation of corneal ring infiltrate in a patient with cytomegalovirus (CMV) endotheliitis. Methods: Single interventional case report. Results: A 37-year-old man presented 6-month history multiple recurrent attacks inflammatory glaucoma both eyes. diagnosis Posner-Schlossman syndrome was made 10 years previously. Slit-lamp examination showed well-defined patch endotheliitis and some keratic precipitates corneas. The intraocular pressure elevated Aqueous humor...