A5100333906- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Radiopharmaceutical Chemistry and Applications
- Atrial Fibrillation Management and Outcomes
- Alzheimer's disease research and treatments
- Neuroscience and Neuropharmacology Research
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Tracheal and airway disorders
- Musicians’ Health and Performance
- Innovations in Medical Education
- Congenital Heart Disease Studies
- Adrenal Hormones and Disorders
- Healthcare Systems and Technology
- Cardiovascular Function and Risk Factors
- Computational Drug Discovery Methods
- Hormonal Regulation and Hypertension
- Clinical Reasoning and Diagnostic Skills
- Chemotherapy-related skin toxicity
- HER2/EGFR in Cancer Research
- Anesthesia and Pain Management
- Motor Control and Adaptation
- Dental Anxiety and Anesthesia Techniques
- HIV/AIDS drug development and treatment
- Reconstructive Surgery and Microvascular Techniques
University Hospitals of Cleveland
2025
Kaiser Permanente
2022-2024
University Hospital of Lausanne
2024
California State University, Fullerton
2024
Stanford University
2023
Yale University
2022-2023
Mayo Clinic in Arizona
1995-2023
Touro College
2021-2023
Johns Hopkins University
2022
Mayo Clinic Hospital
2021
Satellite glia are the major glial cells in sympathetic ganglia, enveloping neuronal cell bodies. Despite this intimate association, extent to which functions influenced by satellite vivo remains unclear. Here, we show that critical for metabolism, survival, and activity of neurons modulate autonomic behaviors mice. Adult ablation results impaired mTOR signaling, soma atrophy, reduced noradrenergic enzymes, loss neurons. However, persisting have elevated activity, glia-ablated mice increased...
The opioid overdose crisis had progressed broadly in the United States, with an 21% increase from 2016 to 2017, and specifically Massachusetts, a peak rate of 1,374 deaths 2016. In 2016, students faculty at Harvard Medical School (HMS) established Substance Use Pain Curriculum Committee (SUPCC) expand substance use pain education. However, capacity, financial resources, administrative support were insufficient implement changes across all phases medical school curriculum. HMS SUPCC...
IMPORTANCE Insurers are increasingly deploying “narrow networks” with fewer contracted physicians both in health plans offered new state exchanges under the Affordable Care Act and Medicare Advantage (MA) plans, which commercial alternatives to beneficiaries. Patients choosing rely on accuracy of network directories posted by insurers. The MA must meet adequacy requirements,and inaccurate participating might prejudice those determinations.OBJECTIVE To determine plan dermatologists,and...
Heart failure is a leading cause of death, yet its underlying electrophysiological (EP) mechanisms are not well understood. In this study, we use multiscale approach to analyze model heart and connect results features the electrocardiogram (ECG). The derived by modifying previously validated electrophysiology for healthy rabbit heart. Specifically, in accordance with literature, modified cell EP changing both membrane currents calcium handling. At tissue level, modeled increased gap junction...
Chronic obstructive pulmonary disease (COPD) has been shown to be associated with lower levels of vitamin D, and the latter total cardiovascular (CVD) mortality.We hypothesized that D will further enhance association COPD its severity CVD studied 7746 US adults age ≥40 years without known (mean age, 59.8 years) followed up through 2006 (8.2 ± 2.5 for mortality. Serum 25-hydroxyvitamin were categorized as tertiles: first tertile, <50.9 nm/L; second 50.9 73.6 third >73.6 nm/L. Severity was...
Background: The objective of this study was to evaluate if anticoagulation therapy reduces recurrent stroke in embolic undetermined source (ESUS) patients with left atrial enlargement (LAE) or abnormal markers coagulation and hemostatic activity (MOCHA) compared antiplatelet therapy. Methods: ESUS from January 1, 2017, June 30, 2019, underwent outpatient cardiac monitoring the MOCHA profile (serum d -dimer, prothrombin fragment 1.2, thrombin–antithrombin complex, fibrin monomer)....
Objectives: Tenecteplase is a fibrin-specific plasminogen activator that has shown promising results in the treatment of acute ischemic stroke. been suggested to reduce door-to-needle time and increase rate spontaneous recanalization. In February 2021, Mayo Clinic Health System switched as standard thrombolytic therapy for Methods: this center-based observational cohort study, we present clinical characteristics outcomes patients with stroke treated tenecteplase between 2021 May 2022...
Background The current global trend of growth in medical training is increasing the demand for teaching and supervision students junior doctors. If well trained supported, doctors represent an important resource. Unfortunately, there limited evidence available on whether Australian are equipped with skills. This study aimed to gain insight into type amount teaching-skills peer-to-peer present schools. Methods A survey schools was conducted between May December 2014. An online 22-item...
Background Transdermal lidocaine patches have few systemic toxicities and may be useful analgesics in cardiac surgery patients. However, studies evaluated their efficacy the perioperative setting. Objective To compare of topical 5% patch plus standard care (opioid nonopioid analgesics) with alone for postthoracotomy or poststernotomy pain adult patients a cardiothoracic intensive unit. Methods A single-center, retrospective cohort evaluation was conducted from January 2015 through December...
Introduction Synapse loss is one of the hallmarks Alzheimer's disease (AD) and associated with cognitive decline. In this study, we tested [ 18 F]SDM-16, a novel metabolically stable SV2A PET imaging probe, in transgenic APPswe/PS1dE9 (APP/PS1) mouse model AD age-matched wild-type (WT) mice at 12 months age. Methods Based on previous preclinical studies using 11 C]UCB-J F]SynVesT-1 same strain animals, used simplified reference tissue (SRTM), brain stem as pseudo region to calculate...
Background: Persons living with human immunodeficiency virus (HIV) (PWH) on antiretroviral therapy (ART) are frequently admitted to the intensive care unit (ICU). HIV ART may be at higher risk for potential drug-drug interactions (pDDIs) due polypharmacy in ICU. We determined prevalence of pDDI critically ill PWH. Objectives: The primary outcome was between and ICU medications. Secondary outcomes included per admission, severity, ICU, hospital length stay (LOS). Methods: A single-center,...