A5093254249- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Viral gastroenteritis research and epidemiology
- Viral Infections and Vectors
- T-cell and Retrovirus Studies
- Plant and Fungal Interactions Research
- Animal Virus Infections Studies
- Viral Infections and Immunology Research
Plum Island Animal Disease Center
2023-2024
Oak Ridge Associated Universities
2023-2024
Oak Ridge Institute for Science and Education
2023-2024
United States Department of Agriculture
2023
Agricultural Research Service
2023
The African swine fever virus (ASFV) is currently causing a world-wide pandemic of highly lethal disease in domestic and wild boar. Currently, recombinant ASF live-attenuated vaccines based on genotype II strain are commercially available Vietnam. With 25 reported ASFV genotypes the literature, it important to understand molecular basis usefulness genotyping, as well true significance epidemiology, transmission, evolution, control, prevention ASFV. Historically, genotyping was used for...
In 2007, an outbreak of African swine fever (ASF), a deadly disease domestic and wild boar caused by the virus (ASFV), occurred in Georgia has since spread globally. Historically, ASFV was classified into 25 different genotypes. However, newly proposed system recategorized all isolates 6 genotypes exclusively using predicted protein sequences p72. large genome that encodes between 150-200 genes, classifications single gene are insufficient misleading, as strains encoding identical p72 often...
Historically, genotyping of African swine fever virus was based on partial sequencing B646L (p72). Until recently, the number differences that defined genotypes ambiguous. This tool allows a sequence to be uploaded and will report its closest matches along with likely p72 genotype.
Obtaining a complete good-quality sequence and annotation for the long double-stranded DNA genome of African swine fever virus (ASFV) from next-generation sequencing (NGS) technology has proven difficult, despite increasing availability reference sequences affordability NGS. A gap analysis conducted by global research alliance (GARA) partners identified that standardized, automatic pipeline NGS was urgently needed, particularly new outbreak strains. Whilst there are several diagnostic labs...
African swine fever virus biotyping is a recently described classification technique that based on an isolate's encoded proteome. In short, proteomes are compared and grouped unsupervised machine learning. This tool analyzes (ASFV) genomes will report their closest matches along with ASFV biotypes. Here, we describe standalone implementation can be freely downloaded used.