- Protein Hydrolysis and Bioactive Peptides
- Food Quality and Safety Studies
- Ginseng Biological Effects and Applications
- Biochemical effects in animals
- Phytochemicals and Antioxidant Activities
- Fungal Biology and Applications
- Pharmacological Effects of Natural Compounds
- Polysaccharides and Plant Cell Walls
- GABA and Rice Research
- Biochemical Analysis and Sensing Techniques
- Skin Protection and Aging
- Microbial Metabolites in Food Biotechnology
- Diet and metabolism studies
- Phytoestrogen effects and research
- Seaweed-derived Bioactive Compounds
- Tea Polyphenols and Effects
- Nutrition, Health and Food Behavior
- melanin and skin pigmentation
- Gastrointestinal motility and disorders
- Probiotics and Fermented Foods
- Enzyme Production and Characterization
- Sleep and Wakefulness Research
- Gut microbiota and health
- Bee Products Chemical Analysis
- Food composition and properties
Korea University
2016-2025
Korea National University of Transportation
2022
Graduate School USA
2020-2021
Seoul Institute
2020-2021
Government of the Republic of Korea
2015-2021
Food and Nutrition Service
2015
Daegu Technical University
2011
Catholic University of Korea
2010
Dongduk Women's University
2009
Hankyong National University
2008
γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter and it well established that activation of GABAA receptors favours sleep. l-Theanine, a naturally occurring amino first discovered in green tea, well-known anti-anxiety supplement with proven relaxation benefits.This study investigated potential synergistic sleep enhancement effect GABA/l-theanine mixture.Pentobarbital-induced test was applied to find proper concentration for sleep-promoting ICR mice. Electroencephalogram...
This study investigated the effects of Lactobacillus brevis-fermented gamma-aminobutyric acid (LB-GABA) on depressive and anxiety-like behaviors with underlying molecular mechanism in a chronic stress model BALB/c mice. LB-GABA attenuates both neuronal cell death increase monoamine oxidase activity induced by hydrogen peroxide. Behavioral tests revealed that GABA significantly increased sucrose preference reduced immobility time tail suspension forced swimming tests. exploration open arms...
The objective of this study was to evaluate the anti-aging potential and skin safety red ginseng (RG) fermented (FRG) using Lactobacillus brevis for use as cosmetic ingredients. Concentrations uronic acid, polyphenols, flavonoids, antioxidant activities were greater in FRG compared RG. contents total ginsenosides not significantly different. However, ginsenoside metabolite content higher (14,914.3 μg/mL) RG (5697.9 μg/mL). tyrosinase inhibitory activity (IC50) 27.63 μg/mL, more potent with...
This study was conducted to investigate the hypocholesterolemic effect of hot-water fraction (HW) from cultured mycelia Cordyceps sinensis in a 5 l fermenter. The composition HW mainly carbohydrate (83.9%) and protein (11.8%) on dry basis, consisted glucose, mannose, galactose, arabinose molecular ratio 1.0 : 0.8 0.5 0.1, respectively. In mice fed cholesterol-free diet those cholesterol-enriched diet, body liver weights were not significantly different controls. serum total cholesterol (TC)...
The anti-stress and anti-fatigue effects of a hot water extract fermented rice bran (FRB) were investigated with Saccharomyces cerevisae IFO 2346 on rats or mice. Oral administration (1 g/kg/day) FRB inhibited major changes in weight the adrenal, thymus, spleen thyroid, showing effect. A also increase GPT LDH activity, cholesterol serum glucose levels. Administration for 2 weeks significantly prolonged swimming time, resulting an From these results, it can be considered that has
BACKGROUND: To determine biomaterial components, the components must first be transferred into solution; thus extraction is step in analysis. High hydrostatic pressure technology was used for ginsenoside from ginseng roots. In of fresh and red ginseng, high (HHPE) found to more effective than heat (HE). RESULTS: under HHPE, total ginsenosides (1602.2 µg mL−1) metabolite (132.6 levels were slightly higher those HE (1259.0 78.7 mL−1), respectively. similar results indicated amounts according...
Green tea contains numerous polyphenols, which have health-promoting effects. The purpose of this study was to evaluate the effect tannase-converted green extract (TGE) formulation on physical stability and activities skin-related enzymes.Physical evaluated by measuring pH, precipitation, colors at 25 ± 2 °C/ambient humidity 40 °C/70% 5% relative for 4 months. Activities collagenase, elastase, tyrosinase as enzymes were assessed TGE formulation.The concentrations epigallocatechin-3-gallate...
This study describes increases in extraction efficiency and the bioconversion of catechins after treatment with several commercial enzymes. Tannase was also used to improve anti-radical activities green tea extracts. Enzymatic various enzymes introduced polyphenols. The total polyphenol, flavonoid, catechin contents 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity extract treated Viscozyme (VG) were significantly higher than those other enzymatic extractions (p<0.05). More...
Scope Punicalagin (PCG) is one of the most abundant phytochemicals found in pomegranates. The effects and mechanistic action PCG on obesity obesity‐induced inflammatory oxidant responses are investigated vitro vivo. Methods results effect adipogenesis examined using Oil red O staining. mechanism determined adipocyte‐conditioned medium (ACM)‐cultured macrophages, a cell‐to‐cell contact system, transwell system. inflammatory/oxidant high‐fat diet (HFD)‐fed mice. effectively suppresses lipid...