A5100376339- Multiple Myeloma Research and Treatments
- Adipose Tissue and Metabolism
- Dyeing and Modifying Textile Fibers
- Combustion and flame dynamics
- Antimicrobial Peptides and Activities
- Monoclonal and Polyclonal Antibodies Research
- Protein Hydrolysis and Bioactive Peptides
- Ginseng Biological Effects and Applications
- Advanced Combustion Engine Technologies
- Sirtuins and Resveratrol in Medicine
- Acute Myeloid Leukemia Research
- Seaweed-derived Bioactive Compounds
- Glycosylation and Glycoproteins Research
- Rocket and propulsion systems research
- Chronic Myeloid Leukemia Treatments
- Radiative Heat Transfer Studies
- Exercise and Physiological Responses
- Skin Protection and Aging
- Erosion and Abrasive Machining
- Fungal Biology and Applications
- Adipokines, Inflammation, and Metabolic Diseases
- Cassava research and cyanide
- Biomedical Ethics and Regulation
- Nutrition, Health and Food Behavior
- Inertial Sensor and Navigation
Research Institute of Industrial Science and Technology
2022
Pukyong National University
2014-2019
Hanyang University
2018
Sungkyunkwan University
2016-2018
Kyung Hee University
2017
Seoul National University
2003-2014
Gachon University Gil Medical Center
2008-2014
Seoul Media Institute of Technology
2003
Gynostemma pentaphyllum is widely used in Asia as a herbal medicine to treat type 2 diabetes, dyslipidemia, and inflammation. Here, we investigated the anti-obesity effect underlying mechanism of G. extract (GPE) enriched gypenoside L, LI, ginsenoside Rg3 obtained using novel extraction method. Five-week-old male C57BL/6N mice were fed control diet (CD), high-fat (HFD), HFD + 100 mg/kg body weight (BW)/day GPE (GPE 100), 300 BW/day 300), or 30 Orlistat (Orlistat 30) for 8 weeks. The HFD-fed...
Peroxisome proliferator-activated receptor-gamma co-activator-1α (PGC-1α) has a central role in regulating muscle differentiation and mitochondrial metabolism. PGC-1α stimulates growth fiber remodeling, concomitantly lactate lipid metabolism promoting oxidative Gynostemma pentaphyllum (Thumb.) been widely employed as traditional herbal medicine possesses antioxidant, anti-obesity, anti-inflammatory, hypolipemic, hypoglycemic, anticancer properties. We investigated whether G. extract (GPE)...
The skin is the outermost organ of human body and plays a protective role against external environmental damages, such as sunlight pollution, which affect anti-oxidant defenses inflammation, resulting in erythema or reddening, immunosuppression, epidermal DNA damage.The present study aimed to investigate potential effects red orange complex H extract (ROC) ultraviolet (UV)-induced photoaging Skh:HR-2 mice. ROC was orally administered at doses 20, 40, 80 mg/kg/day for 13 weeks, along with UV...
The effectiveness of natural compounds in improving athletic ability has attracted attention both sports and research. Gynostemma pentaphyllum (Thunb.) leaves are used to make traditional herbal medicines Asia. active components G. pentaphyllum, dammarane saponins, or gypenosides, possess a range biological activities. On the other hand, anti-fatigue effects from extract (GPE) its effective compound, gypenoside L (GL), remain be determined.This study examined GPE on fatigue exercise...
Mori Folium (Morus alba leaf, MF) and Cortex Radicis root cortex, MR) have been studied for their anti-obesity effects by enhancing the browning process inhibiting adipogenesis. However, important aspects of protective mechanisms not thoroughly investigated, which could aid in developing functional food. Thus, this study aims to determine synergistic MF MR against obesity its associated mechanisms. In an vitro cell culture model brown adipocytes, a 1:1 mixture showed effect on expression...
Long-term hepatic damage is associated with human morbidity and mortality owing to numerous pathogenic factors. A variety of studies have focused on improving liver health using natural products herbal medicines. We aimed investigate the effect enzyme-treated Zizania latifolia ethanol extract (ETZL), which increases content tricin via enzymatic hydrolysis, for 8 weeks liver-related outcomes, lipid metabolism, antioxidant activity, fatigue compared a placebo. Healthy Korean adult males aged...
Activating brown adipose tissue (BAT) and stimulating white (WAT) browning is a prospective obesity treatment method. Dietary components derived from plants are the most effective approach to activate BAT promote WAT in rodents. This study investigated synergistic effects of Panax ginseng (PG) Diospyros kaki leaf (DKL) extract on adipocyte differentiation browning, as well molecular mechanism underlying their beneficial effects. The administration PG DKL HFD-induced obese mice significantly...
Ensuring uniform addition of coloring material to the fabric is an essential requirement in textile dyeing process. Beam machine consists a special beam, barrel which evenly perforated with holes. The dye liquor forced into through this beam. For coloring, equal distribution porous beam has be ensured. present methodology employs theoretical and computational fluid dynamics aspects process obtain better performance. analysis single row branches shows that nonuniformity increases increase...
The stability of inverse nonpremixed oxygen (O2)/methane (CH4) coaxial jet flames near blowout limits in a model combustor is studied by analyzing signals for their local combustion phenomena using high-speed imaging and dynamic pressure. power spectral analysis the statistical are conducted to delineate flames. Depending on O2 CH4 momentum flux ratio ((O/F)mom), two distinguished which lead different liftoff mechanisms observed same burner configuration: partial related aerodynamic...
아무르불가사리(Asterias amurensis)의 6가지의 조직 추출물들을 사용하여 항균활성, 항산화 활성 및 평활근에 대한 수축과 이완반응에 활성을 측정하였다. 1% (v/v) 초산용액을 동결 건조한 샘플들을 추출하여 각각의 활성측정에 사용한 결과, 껍질을 제외한 모든 추출물들은 E. coli D31에 대해 강한 항균활성을 나타내었고, 근육 장관 별불가사리(Asterina pectinifera)의 DRM에 수축반응을 나타냈다. 한편, 오징어(Todarodes pacificus) 식도에 수축반응은 실험에 추출물들에서 검출되었다. 특히, 간 추출물의 수축활성은 다른 조직의 활성에 비해 더 높았다. 뿐만 아니라 간, 소화관 추출물은 졸복(Takifugu pardalis)의 장관에 대해서 별불가사리의 이완반응은 활성은 장관, 껍질의 강하게 나타났다. 따라서 아무르불가사리는 새로운 생체기능 조절물질의 발견에 가능성을 지닌 자원이라는 것을 본 연구의 결과들은 제시한다....