Jaesun Lee

ORCID: 0000-0001-6857-4092
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About
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Research Areas
  • Ginseng Biological Effects and Applications
  • Pharmacological Effects of Natural Compounds
  • Biological and pharmacological studies of plants
  • Magnolia and Illicium research
  • Gastrointestinal Tumor Research and Treatment
  • Pediatric Hepatobiliary Diseases and Treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Exercise and Physiological Responses
  • Natural Antidiabetic Agents Studies
  • Gastrointestinal disorders and treatments
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Adipose Tissue and Metabolism
  • Sirtuins and Resveratrol in Medicine
  • Drug Transport and Resistance Mechanisms
  • Gut microbiota and health
  • Phytochemicals and Antioxidant Activities

Konyang University
2022-2023

Daegu TechnoPark
2022

Hallym University
2019-2020

Bile acids are synthesized from cholesterol and play an important role in regulating intestinal microflora. The different degrees of hydrophobicity acidity individual bile may affect their antimicrobial properties. We examined the effects on various microorganisms vitro confirmed whether these remain consistent vivo. Using human acids, including ursodeoxycholic acid, cholic chenodeoxycholic deoxycholic lithocholic a disc diffusion test was performed, rodent model created to determine each...

10.3390/microorganisms10091792 article EN cc-by Microorganisms 2022-09-06

Individual differences in ginsenoside pharmacokinetics following ginseng administration humans are still unclear. We aimed to investigate the pharmacokinetic properties of various ginsenosides, including Rb1, Rg3, Rg5, Rk1, F2, and compound K (CK), after a single oral red (RG) bioconverted extract (BRG). This was randomized, open-label, single-dose, single-sequence crossover study with washout every 1 week, 14 healthy Korean men were enrolled. All subjects equally assigned two groups given...

10.1155/2022/8427519 article EN Evidence-based Complementary and Alternative Medicine 2022-01-24

Peroxisome proliferator-activated receptor-gamma co-activator-1α (PGC-1α) has a central role in regulating muscle differentiation and mitochondrial metabolism. PGC-1α stimulates growth fiber remodeling, concomitantly lactate lipid metabolism promoting oxidative Gynostemma pentaphyllum (Thumb.) been widely employed as traditional herbal medicine possesses antioxidant, anti-obesity, anti-inflammatory, hypolipemic, hypoglycemic, anticancer properties. We investigated whether G. extract (GPE)...

10.4162/nrp.2022.16.1.14 article EN Nutrition Research and Practice 2022-01-01

Anti-obesity activities of Korean red ginseng saponin fraction (RGS) and/or Glycyrrhiza glabra L. extract (GG) were investigated in 3T3-L1 adipocytes and high-fat diet-induced C57BL/6J obese mice. RGS GG extracts mixed at a mass ratio 3:1 (SG31), 1:1 (SG11), or 1:3 (SG13). SG31 showed the highest anti-obesity activity among three different ratios extracts. higher inhibition efficiency on triglyceride (TG) accumulation than either single without any cytotoxicity. It also decreases expression...

10.1089/jmf.2019.4660 article EN Journal of Medicinal Food 2020-03-01

In patients with obscure gastrointestinal bleeding, re-examination standard upper endoscopes by experienced physicians will identify culprit lesions in a substantial proportion of patients. A common practice is to insert an adult-sized forward-viewing endoscope into the second part duodenum. When tip enters after papilla, which marker for descending duodenum, it difficult endoscopically judge how far duodenum has been traversed beyond part.We three cases proximal jejunal masses that were...

10.12998/wjcc.v11.i4.962 article EN World Journal of Clinical Cases 2023-02-03
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