A5069473386- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Neuroscience of respiration and sleep
- Pediatric health and respiratory diseases
- Airway Management and Intubation Techniques
- Infant Development and Preterm Care
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Air Quality and Health Impacts
- Peripheral Nerve Disorders
- Tracheal and airway disorders
- Urinary and Genital Oncology Studies
- Urinary Tract Infections Management
- Reproductive tract infections research
- Urologic and reproductive health conditions
- Infection Control and Ventilation
- Nerve Injury and Rehabilitation
- Preterm Birth and Chorioamnionitis
- Uterine Myomas and Treatments
- Fibroblast Growth Factor Research
- Endometrial and Cervical Cancer Treatments
- Infant Nutrition and Health
- Salivary Gland Disorders and Functions
- Congenital Anomalies and Fetal Surgery
- Obstructive Sleep Apnea Research
Penn State Milton S. Hershey Medical Center
2020-2024
Westchester Medical Center
2019-2024
Maria Fareri Children's Hospital
2019-2024
New York Medical College
2019-2024
Pennsylvania State University
2020-2024
Maimonides Medical Center
2014-2017
Radial tunnel syndrome (RTS) is a rare disease which should be considered in elbow and forearm pain. It presents with lateral dorsal pain may radiated to wrist dorsum of the finger. caused by intermittent compression on radial nerve (RN) from head inferior border supinator muscle, without obvious extensor muscle weakness. Electrodiagnostic test imaging studies helpful diagnosis these problems. This case report successful management RTS using ultrasoundguided perineuronal hydro dissection...
Background: Hypersensitivity pneumonitis (HP) is an interstitial lung disease caused by inhalation of common environmental organic particles. Surfactant proteins (SPs) play a role in innate immunity and surfactant function. We hypothesized that single nucleotide polymorphisms (SNPs) or haplotypes the SP genes associate with HP. Methods: Seventy-five HP patients avian antigen 258 controls, asymptomatic exposed non-exposed were enrolled. SNP association was performed using logistic regression...
Prolonged labor can lead to infection, fetal distress, asphyxia, and life-threatening harm both the mother baby. Surfactant protein A (SP-A) was shown contribute maintenance of pregnancy timing term labor. SP-A modulates stoichiometric expression SP-R210
Co-enzyme nicotinamide adenine dinucleotide (NAD(H)) redox plays a key role in macrophage function. Surfactant protein (SP-) A modulates the functions of alveolar macrophages (AM) and ozone (O3) exposure presence or absence SP-A reduces mouse survival sex-dependent manner. It is unclear whether how NAD(H) status innate immune response We investigated AM from SP-A2 knockout (KO) mice to O3 filtered air (control) using optical imaging technique. found: (i) In mice, alteration showed...
Background: Neonatal respiratory distress syndrome (RDS), due to surfactant deficiency in preterm infants, is the most common cause of morbidity. The proteins (SFTP) genetic variants have been well-studied association with RDS; however, impact SNP-SNP (single nucleotide polymorphism) interactions on RDS has not addressed. Therefore, this study utilizes a newer statistical model determine SFTP single SNP and two three interaction susceptibility. Methods: This used available genotype clinical...
Employing the optical redox imaging technique, we previously identified a significant shift of nicotinamide adenine dinucleotide (NAD and reduced form NADH) in freshly isolated alveolar macrophages (AM) from ozone-exposed mice. The goal here was twofold: (a) to determine NAD(H) cryopreserved AM mice (b) investigate whether there is difference status between AM. We found: (i) were more oxidized state compared that filtered air (FA)-exposed mice, consistent with results obtained mouse AM; (ii)...
Abstract Background Infantile botulism (IB) is a devastating and potentially life-threatening neuromuscular disorder resulting from intestinal colonization by Clostridium botulinum the resultant toxin production. It can present with constipation, descending paralysis, and, potentially, respiratory failure. Botulism diagnosis that more commonly seen in pediatric intensive care unit (PICU) or on general wards would not typically be managed neonatal (NICU), therefore requires high clinical...
This perspective work by academic neonatal providers is written specifically for the audience of newborn care and neonatologists involved in hypoglycemia screening. Herein, we propose adding a screen congenital hyperinsulinism (CHI) measuring glucose ketone (i.e., β-hydroxybutyrate (BOHB)) concentrations just prior to hospital discharge as close 48 h after birth possible, at same time that mandated state Newborn Dried Blood Spot Screen obtained. In proposed protocol, do not recommend...
CPAP benefits preterm infants with respiratory distress, including reduced bronchopulmonary dysplasia (BPD) incidence, surfactant use, and extubation failure. Successful weaning also promotes oral feeding. However, there is no consensus on the optimal of in neonates. This study aimed to determine effects guideline implementation neonatal outcomes. gradual pressure guidelines were implemented Penn State Children's Hospital ICU 2020. We included baseline data from (epoch 1) before 2018-2019....
This study investigates the effectiveness of extubation from conventional mechanical ventilation using an endotracheal tube (MVET) compared to synchronized non-invasive positive-pressure (sNIPPV) neurally adjusted ventilatory assist (NAVA) and (NIPPV) in extremely low-birth-weight (ELBW) infants.
Background-Bronchopulmonary dysplasia (BPD) is a condition of poor alveolar formation that causes chronic breathing impairment in infants born prematurely. Preterm lungs lack surfactant and are vulnerable to oxidative injuries driving the development BPD. Our recent studies reported protein A (SP-A) genetic variants influence susceptibility neonatal lung disease. SP-A modulates activation macrophages parturition onset late gestation. We asked whether alters alveolarization mouse model...
Bronchopulmonary dysplasia (BPD) is a condition of poor alveolar formation that causes chronic breathing impairment in infants born prematurely. Preterm lungs lack surfactant and are vulnerable to oxidative injuries driving the development BPD. Our recent studies reported protein A (SP-A) genetic variants influence susceptibility neonatal lung disease. SP-A modulates activation macrophages parturition onset late gestation. We asked whether alters alveolarization mouse model hyperoxia-induced...
Background: MicroRNAs (miRNA) are small non-coding RNAs that regulate gene expression playing a key role in organogenesis. MiRNAs studied tracheal aspirates (TA) of preterm infants. However; this is difficult to obtain infants who not intubated. This study examines early salivary miRNA as non-invasive biomarkers extremely low gestational age newborns (ELGANs). Methods: Saliva was collected using DNA-genotek swabs, miRNAs were analyzed RNA seq and RT PCR arrays. Salivary compared TA at 3 days...
Abstract: We happened to manage a case of acute urinary retention that was relieved by drainage 2L urine and sent home attend out patient Gynecology department next day after the ultrasound diagnosis huge myoma. This came be cervical myoma filled vagina pushing uterus up level umbilicus. is in reference general interest everybody any woman suffering having gynecological bearing must well evaluated before disposing them without inserting indwelling catheter.