- Heart Failure Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Heart Rate Variability and Autonomic Control
- ECG Monitoring and Analysis
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Cardiac Health and Mental Health
- Cardiac, Anesthesia and Surgical Outcomes
- Blood Pressure and Hypertension Studies
- Lipoproteins and Cardiovascular Health
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Health Systems, Economic Evaluations, Quality of Life
- Antiplatelet Therapy and Cardiovascular Diseases
- Animal Behavior and Welfare Studies
- Anesthesia and Sedative Agents
- EEG and Brain-Computer Interfaces
- Aortic Disease and Treatment Approaches
- Anesthesia and Pain Management
- Neuroscience and Neuropharmacology Research
Massachusetts General Hospital
2015-2025
Harvard University
2010-2025
Universidad de Cádiz
2009-2024
Hospital Universitario Puerta del Mar
2015-2024
Temple University
2024
Biomedical Research and Innovation Institute of Cadiz
2018-2024
Fundació Clínic per a la Recerca Biomèdica
2024
Universitat Autònoma de Barcelona
2024
Instituto de Investigación Biomédica de A Coruña
2022
Centro de Investigación en Red en Enfermedades Cardiovasculares
2020-2021
Background. N-terminal fragment of B-type natriuretic peptide (NT-proBNP) is a marker both fluid volume overload and myocardial damage, it has been useful as predictor mortality in patients with end-stage renal disease (ESRD). It suggested that continuous ambulatory peritoneal dialysis (CAPD), automated (APD) haemodialysis (HD) may have different effects on blood pressure control; however, whether the independent predictive value NT-proBNP for preserved when analysed conjunction modality not...
AimsThe prognosis of chronic heart failure (CHF) is extremely variable, although generally poor. The purpose this study was to develop prognostic models for CHF patients.
Electroencephalogram patterns observed during sedation with dexmedetomidine appear similar to those general anesthesia propofol. This is evident the occurrence of slow (0.1 1 Hz), delta (1 4 propofol-induced alpha (8 12 and dexmedetomidine-induced spindle (12 16 Hz) oscillations. However, these drugs have different molecular mechanisms behavioral properties are likely accompanied by distinguishing neural circuit dynamics.
Understanding the neural basis of consciousness is fundamental to neuroscience research. Disruptions in cortico-cortical connectivity have been suggested as a primary mechanism unconsciousness. By using novel combination positron emission tomography and functional magnetic resonance imaging, we studied anesthesia-induced unconsciousness recovery α2-agonist dexmedetomidine. During unconsciousness, cerebral metabolic rate glucose blood flow were preferentially decreased thalamus, Default Mode...
With an estimated 12 million consumers in Europe, cocaine (COC) is the illicit drug leading to most emergency department visits. The aim of this study was examine a consecutive series sudden deaths (SDs) focus on prevalence, toxicological characteristics, and causes death COC-related fatalities. Prospective case–control forensic autopsies carried out time interval November 2003 June 2006 at Institute Legal Medicine, Seville, south-west Spain, with reference population 1 875 462 inhabitants....
Transradial access is the approach of choice in many laboratories for diagnostic coronariography or percutaneous coronary interventions (PCI) because its lower vascular complication rate than femoral approach. However, this has a higher (5-10%) asymptomatic radial artery (RA) occlusion.We conducted prospective, controlled, single-centre trial study. We investigated whether pneumatic compression (using "TR Band Terumo") guided by mean pressure (MAP) after procedure (group A) efficient...
An improved understanding of the neural correlates altered arousal states is fundamental for precise brain state targeting in clinical settings. More specifically, electroencephalogram recordings are now increasingly being used to relate drug-specific oscillatory dynamics clinically desired states. Dexmedetomidine an anesthetic adjunct typically administered operating rooms and intensive care units produce maintain a sedative state. However, high-density characterization...
Parotid gland carcinoma is an infrequent tumor, and series that report on these neoplasms are relatively scarce in the literature. The objective of current study was to identify prognostic factors patients with parotid develop a method for defining probability recurrence.Patients who were treated at authors' institution from January 1981 through December 2004 completed treatment constituted group. Disease-free survival calculated by using Kaplan-Meier method. Logistic regression analysis...
The goal of the present study was to determine predictive value beat-to-beat QT variability in heart failure patients across continuum left ventricular dysfunction.Beat-to-beat index (QTVI), log-transformed rate variance, normalized and coherence between have been measured at rest during sinus rhythm 533 participants Muerte Subita en Insuficiencia Cardiaca (mean age, 63.1±11.7; men, 70.6%; ejection fraction >35% 254 [48%]) 181 healthy from Intercity Digital Electrocardiogram Alliance...
Prevention of hospital readmissions is one the main objectives in management patients with heart failure (HF). Most models predicting are based on data extracted from hospitalized rather than outpatients. Our objective was to develop a validated score 1-month and 1-year risk readmission for worsening HF ambulatory patients.A cohort 2507 chronic prospectively followed median 3.3 years. Clinical, echocardiographic, ECG, biochemical variables were used competing regression analysis construct...
High-frequency jet ventilation (HFJV) facilitates accurate probe placement in percutaneous ablation of lung tumors but may increase risk for adverse events, including systemic air embolism.
Abstract Understanding anesthetic mechanisms with the goal of producing states limited systemic side effects is a major objective neuroscience research in anesthesiology. Coherent frontal alpha oscillations have been postulated as mechanism sevoflurane general anesthesia. This postulate remains unproven. Therefore, we performed single-site, randomized, cross-over, high-density electroencephalogram study and sevoflurane- plus -ketamine anesthesia 12 healthy subjects. Data were analyzed...
Background Coronary heart disease is one of the leading causes mortality worldwide. Secondary prevention essential, as it reduces risk further coronary events. Mobile health (mHealth) technology could become a useful tool to improve lifestyles. Objective This study aimed evaluate effect an mHealth intervention on people with who received percutaneous intervention. Improvements in lifestyle regarding diet, physical activity, and smoking; level knowledge healthy control cardiovascular factors...
In industrialized countries with aging populations, heart failure affects 0.3-2% of the general population. The investigation 24 h-ECG recordings revealed potential nonlinear indices rate variability (HRV) for enhanced risk stratification in patients ischemic (IHF). However, long-term analyses are time-consuming, expensive, and delay initial diagnosis. objective this study was to investigate whether 30 min short-term HRV analysis is sufficient comparable IHF comparison h-HRV analysis. From...