A5100323382- Reproductive Biology and Fertility
- Neuroscience of respiration and sleep
- Pluripotent Stem Cells Research
- Obstructive Sleep Apnea Research
- Sperm and Testicular Function
- Ovarian function and disorders
- Epigenetics and DNA Methylation
- Assisted Reproductive Technology and Twin Pregnancy
- Nanocomposite Films for Food Packaging
- Renal and related cancers
- Animal Genetics and Reproduction
- Birth, Development, and Health
- Diet and metabolism studies
- Estrogen and related hormone effects
- Wnt/β-catenin signaling in development and cancer
- Dietary Effects on Health
- Cardiovascular and Diving-Related Complications
- Plant-Microbe Interactions and Immunity
- Microplastics and Plastic Pollution
- Circadian rhythm and melatonin
- Reproductive System and Pregnancy
- Effects and risks of endocrine disrupting chemicals
- Heat shock proteins research
- Medicinal Plants and Neuroprotection
- Nematode management and characterization studies
Northwest A&F University
2012-2024
Shanghai University of Medicine and Health Sciences
2024
Ocean University of China
2024
Ministère de l'Agriculture et de la Souveraineté alimentaire
2023
Ministry of Agriculture & Farmers Welfare
2023
Ministry of Agriculture and Agro Based Industry
2023
Qingdao University
2023
Affiliated Hospital of Qingdao University
2023
Fuwai Yunnan Cardiovascular Hospital
2023
Tongji University
2023
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have enormous potential for the study of human cardiac disorders. However, their physiological immaturity severely limits utility as a model system and adoption drug discovery. Here, we describe maturation media designed to provide oxidative substrates adapted metabolic needs iPSC (hiPSC)-CMs. Compared with conventionally cultured hiPSC-CMs, metabolically matured hiPSC-CMs contract greater force show an increased reliance on...
Abstract Bacterial infection can cause chronic nonhealing wounds, which may be a great threat to public health. It is highly desirable develop an injectable wound dressing hydrogel with multifunctions including self‐healing, remodeling, antibacterial, radical scavenging ability, and excellent photothermal properties promote the regeneration of damaged tissues in clinical practice. In this work, dopamine‐modified gelatin (Gel‐DA) employed for first time as biotemplate enhancing...
Abstract Background Plant health and growth are negatively affected by pathogen invasion; however, plants can dynamically modulate their rhizosphere microbiome adapt to such biotic stresses. Although plant-recruited protective microbes be assembled into synthetic communities for application in the control of plant disease, microbial commonly contain some taxa at low abundance. The roles low-abundance remain unclear; it is also unclear whether all enriched enhance host adaptation environment....
In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this coupling is crucial for the growth development of competent as it mediates transfer metabolic support molecules. However, aging-mediated dysregulation in communication between cells affects oocyte quality. present study, we examined defected germline-soma reduced mRNA levels encoding key structural components transzonal projections (TZPs) maternally aged oocytes. Oral administration melatonin mice...
The Legume-Rhizobium symbiosis has been proposed as a promising technique for the phytoremediation of contaminated soils due to its beneficial activity in symbiotic nitrogen fixation. However, numerous studies have shown that excessive heavy metals reduce efficiency nodulation with Rhizobium and inhibit plant growth. In this study, we aimed evaluate synergistic effects IAA-producing bacteria on Medicago lupulina growth under Cu Zn stress. Pot experiments showed 400 mg kg-1 Cu2 + Zn2 greatly...
Obstructive sleep apnea (OSA), the most common upper-airway disease, is closely associated with risk of cardiovascular diseases. However, early screening OSA a main challenge, relying on polysomnography (PSG) or home test (HSAT) in hospitals. Photoplethysmography (PPG) has been developed as novel technology for OSA, while validation PPG-based smart devices limited compared to that PSG HSAT devices.This study aimed investigate feasibility and validity smartwatch OSA.A total 119 patients were...
Bisphenol A (BPA) is one of the ubiquitous environmental endocrine disruptors (EEDs). Previous studies have shown that reproduction toxicity BPA could cause severe effects on mammal oocytes and disturb quality mature oocytes. However, toxic organelles mouse not been reported. In this study, to investigate whether can be organelles, we used different concentrations (50, 100, 200 μM) culture in vitro . The results showed 100 μM exposure significantly decrease developmental capacity Then,...
Astragalus mongholicus is a widely used Traditional Chinese Medicine. However, cultivated A. often threatened by water shortage at all growth stage, and the content of medicinal compounds much lower than that wild plants. To alleviate drought stress on improve accumulation components in roots mongholicus, we combined different bacteria with plant promotion or abiotic resistance characteristics evaluated role bacterial consortium helping plants tolerate improving component simultaneously....
Abstract Background Ovarian cancer (OC) is one of the most prevalent gynecologic malignancies and exhibites highest fatality rate among all malignancies. The absence an early diagnostic biomarker therapeutic target contributes to overall 5-year survival ranging from 30 50%. Plectin (PLEC), a 500 kDa scaffolding protein, has gained prominence in recent years due its pivotal role various cellular biological functions such as cell morphology, migration adhesion, while accurate PLEC OC remains...
Abstract Estrogen is an important modulator of reproductive activity through nuclear receptors and G protein–coupled estrogen receptor (GPER). Here, we observed that both estradiol the GPER-specific agonist G1 rapidly induced cyclic adenosine monophosphate (cAMP) production in cumulus cells, leading to transient stimulation phosphorylated cAMP response element binding protein (CREB), which was conducive transcription epidermal growth factor (EGF)-like factors, amphiregulin, epiregulin,...
The overall oocyte quality declines with aging, and this effect is strongly associated a higher reactive oxygen species (ROS) level the resultant oxidative damage. C-type natriuretic peptide (CNP) well-characterized physiological meiotic inhibitor that has been successfully used to improve immature during in vitro maturation. However, underlying roles of CNP maternally aged oocytes have not reported. Here, we found age-related reduction serum concentration was highly correlated decreased...
Bone marrow mesenchymal stem cells (BMSCs) can transdifferentiate into different types of and may serve as a cell source for tissue engineering. Resveratrol has been shown to possess many benefits, including activation osteogenesis. Furthermore, Wnt/β-catenin signaling known promote osteogenic differentiation in cells. In this study, we investigated the role resveratrol osteoblastic canine BMSCs. treatment BMSCs remarkably increased alkaline phosphatase activity calcium nodules, inhibited...
OSA is an independent risk factor for several systemic diseases. Compared with mild OSA, patients moderate-to-severe have more severe impairment in the function of all organs body. Due to current limited medical condition, not every patient can be diagnosed and treated time. To enable timely screening we selected easily accessible variables establish a prediction model.We collected 492 who had polysomnography (PSG), divided them into disease-free group (control group), according PSG results....
Objective. The aim of this study was to compare the differences in thyroid hormone, intelligence, attention, and quality life (QoL) children with obstructive sleep apnea hypopnea syndrome (OSAHS) before after endoscopic adenoidectomy. Method. A total 35 OSAHS (21 males 14 females a mean age 6.81 ± 1.08 years) were included for analyzing levels QoL. There 22 underwent adenoidectomy bilateral tonsillectomy (BT), while other 13 who without BT. Results. Our results revealed no significant...
The overall oocyte quality declines with aging, and this effect is strongly associated a higher reactive oxygen species (ROS) level the resultant oxidative damage. C-type natriuretic peptide (CNP) well-characterized physiological meiotic inhibitor that has been successfully used to improve immature during in vitro maturation. However, underlying roles of CNP maternally aged oocytes have not reported. Here, we found age-related reduction serum concentration was highly correlated decreased...