A5102847062- Polyomavirus and related diseases
- Infectious Diseases and Tuberculosis
- Hip disorders and treatments
- Antenna Design and Analysis
- Immune Cell Function and Interaction
- Orthopedic Infections and Treatments
- Full-Duplex Wireless Communications
- Orthopaedic implants and arthroplasty
- Anesthesia and Pain Management
- Monoclonal and Polyclonal Antibodies Research
- Cardiac, Anesthesia and Surgical Outcomes
- Virus-based gene therapy research
- Botulinum Toxin and Related Neurological Disorders
- CAR-T cell therapy research
- Network Security and Intrusion Detection
- Sepsis Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Spinal Fractures and Fixation Techniques
- Immune cells in cancer
- Smart Agriculture and AI
- Parvovirus B19 Infection Studies
- Tendon Structure and Treatment
- Immunotherapy and Immune Responses
- Peripheral Nerve Disorders
- Thyroid and Parathyroid Surgery
ABES Engineering College
2023
Max Healthcare
2023
Institute of Management Technology
2023
All India Institute of Medical Sciences Rishikesh
2021-2022
Galgotias University
2022
Ono Pharmaceutical (United States)
2020-2022
Research & Development Institute
2020-2022
KU Leuven
2022
City University of Hong Kong
2022
Tokushima University
2022
Abstract In this work, we have generated novel Fc-comprising NK cell engagers (NKCEs) that bridge human NKp30 on cells to epidermal growth factor receptor (EGFR) tumor cells. Camelid-derived VHH single-domain Abs specific for and a humanized Fab derived from the EGFR-specific therapeutic Ab cetuximab were used as binding arms. By combining camelid immunization with yeast surface display, able isolate diverse panel of NKp30-specific VHHs against different epitopes NKp30. Intriguingly, NKCEs...
Objectives: Early organ dysfunction in sepsis confers a high risk of in-hospital mortality, but the relative contribution specific types failure to overall mortality is unclear. The objective this study was assess predictive ability individual or prolonged intensive care. Methods: Retrospective cohort adult emergency department patients with from October 1, 2013, November 10, 2015. Multivariable regression used odds ratios for outcomes death (primary) and ICU stay ≥ 3 days (secondary)....
Activating NK cell receptors represent promising target structures to elicit potent antitumor immune responses. In this study, novel immunoligands were generated that bridge the activating receptor NKp30 on cells with epidermal growth factor (EGFR) tumor in a bispecific IgG-like format based affinity-optimized versions of B7-H6 and Fab arm derived from cetuximab. To enhance binding, solitary N-terminal IgV domain (ΔB7-H6) was affinity matured by an evolutionary library approach combined...
To evaluate direct versus indirect monocyte chemoattractant protein (MCP)-1/CCR2 signaling and to identify the cellular producers effectors for MCP-1 during neointimal hyperplasia (NIH) development in vein grafts.Genomic analysis revealed an overrepresentation of 13 inflammatory pathways wild-type grafts compared with CCR2 knockout grafts. Further investigation various graft-host combinations MCP-1- CCR2-deficient mice was used modify genotype cells both inside (graft-intrinsic group)...
Posterolateral decompression and debridement in patients with TB spine led to defect the anterior column which makes spinal unstable, thus making reconstruction an important step surgical management.Through study, authors sought answer following questions: 1) What are differences clinical outcomes between undergoing using titanium mesh cage versus PEEK cage? 2) radiological these two groups of patients?This is a retrospective comparative study including management. The included subjects were...
<b>Background:</b> Spasticity is a syndrome associated with persistent increase in involuntary reflex activity of muscle response to stretch. Adductor spasticity common complication spinal cord and brain injury. It needs be treated if it interferes activities daily living self-care. Obturator neurolytic blockade one the cost-effective therapeutic possibilities treat adductor group muscles. In this study, we assessed efficacy interadductor approach alleviating spasticity. <b>Methods:</b>...
ABSTRACT The E2F family of transcription factors, broadly divided into activator and repressor E2Fs, regulates cell cycle genes. Current models indicate that E2Fs are necessary for progression tumorigenesis also required to mediate transformation induced by DNA tumor viruses. negatively regulated the retinoblastoma (RB) suppressor proteins, virus-encoded oncogenes disrupt RB-E2F complexes. This results in release induction E2F-dependent In agreement, expression large T antigens (TAg) encoded...
Asian nation is that the second giants in population and lots of crops Indian farmers will cultivate Most cotton large numbers however plant disease major drawback within past few decades which leads to a loss crops, their productivity cash additionally. The Cotton leaves square measure littered with malady named genus Cercospora, microorganism blight, Ascochyta Target spot generally observed by could also be long, high-priced inaccurate. {leaf malady|plant disease} Detection Associate...
Electronic survey-based study.The aim of the study was to objectively review variability in prevailing treatment protocols and surgical decision making management patients with spinal tuberculosis (TB) among spine surgeons expertise TB across country.A lack good-quality evidence, ambiguities national guidelines, demand for early rehabilitation a better quality life has led emergence various gray zones TB.Seventeen fellowship-trained experts representing different geographical regions India...
Background: Ovarian tumors and tumor like lesions of ovary frequently form pelvic masses are associated with hormonal manifestations. Clinically or surgically they can mimic malignancy but pathologically could be benign lesions.Methods: The aim present study is to do clinico-histopathological correlation ovarian also evaluate the role serum CA125, HE4 calculate risk algorithm (ROMA), for differentiation malignant tumors.233 cases were studied. Tumors classified according WHO classification....