Stereology (from the Greek stereos = solid) is considered as spatial interpretation of profiles seen in sections. It a multidisciplinary science field dealing with three-dimensional objects appearing on sectional planes metallurgical materials or tissues. supplies practical techniques for obtaining quantitative information about three-dimensional, real-world structures from two-dimensional planar profiles. After acknowledging fact that sections are not true representations real objects, need...

Purpose: Adverse effects on human health caused by electromagnetic fields (EMF) associated with the use of mobile phones, particularly among young people, are increasing all time. The potential deleterious EMF exposure resulting from phones being used in close proximity to brain require particular evaluation. However, only a limited number studies have investigated prenatal development pyramidal cells using melatonin (MEL) and omega-3 (ω-3).Materials methods: We established seven groups...

Number of particles in an organ or region is a valuable data as well the volume. Many techniques have been developed for estimation total number numerical density cells tissues and organs. The quality reliability each method has constantly increased compared to its predecessors. Numerical one parameters that used assess association between structure function. It should be kept mind biological comments derived from dependent on quantitative parameters. As stated previously, most important...

Melatonin is widely studied for its neuroprotective properties in various cellular models, but the optimal dosage therapeutic effects remains poorly defined, especially neuronal cell lines like HT22.Discrepancies literature regarding effective melatonin concentrations necessitate a systematic investigation to establish standardized window that balances efficacy and safety.The aim identify of promotes viability neuroprotection HT22 hippocampal line over exposure times.A quantitative analysis...

This study was conducted to determine the effects of different doses and methods extracorporeal shock wave treatment (ESWT) on sciatic nerve regeneration rat model using unbiased quantitative stereological techniques know which method dose were effective.Twenty-five Wistar albino rats used in experiment. All animals randomly divided into 5 groups. To first group (control, n = 5) ESWT surgery not applied. 2nd (E300*2, 5), twice 300 impulses uESWs (unfocused) 3rd (E500*2, 500 4th fESWs...

Demyelination and subsequent remyelination are well-known mechanisms in multiple sclerosis (MS) pathology. Current research mainly focused on preventing demyelination or regulating the peripheral immune system to protect further damage central nervous system. However, information about another essential mechanism, remyelination, its balance of response within system's boundaries is still limited.In this study, we tried demonstrate effect recently introduced Janus kinase (JAK)-signal...

Abstract The aim of this study is to analyze the effects autogenous dentin graft and mixture platelet-rich fibrin (PRF) applied tooth extraction sockets on bone healing process. A total 57 in 9 patients who were planned be treated with dental implant after evaluated study. Extraction divided randomly into 3 groups for each patient. In first group, filled (Group D). second PRF DP). third left empty as control group C). After months, histological immunohistochemical evaluations performed...

Biofilm is an example of bacterial group behavior. We investigated the effect N-acetylcysteine (NAC) alone and in combination with ciprofloxacin on Pseudomonas aeruginosa biofilm formation. Four groups (each contains six molds) standardized bone cement molds were infected. NAC, each alone, NAC/ciprofloxacin evaluated point inhibiting eradicating capacity using microbiological electron microscopical evaluation techniques. Microbial counts observations showed that NAC formation valuable....

Non-steroidal anti-inflammatory drugs (NSAIDs) can have adverse effects for in both mother and fetus following administration during the prenatal period. If given pregnancy, diclofenac sodium (DS), an NSAID, is may also affect development of central nervous system (CNS) or related structures.Pregnant rats were separated into pure control (PG), saline (SG) groups (DG). A daily dose 1 mg/kg DS mL/kg was injected intraperitoneally to DG SG groups, respectively, from 5th gestation day a 15...

To seek out the bone regeneration effect of human umbilical cord-mesenchymal stem cell (hUC-MSC)-derived exosomes loaded chitosan/hydroxyapatite (CS/HA) scaffold in a rat calvarium model.The hUC-MSC were purified and characterized. The scaffolds prepared by freeze-drying method. Animals divided into five groups, CS/HA/exosome (CS/HA/Exo) transplanted to 5 × 2-mm critical-sized calvarial defects for repair rats. All animals sacrificed at postoperative sixth week. Immunohistochemical...

The purpose of this study is to investigate the potential local administration different doses rosuvastatin (RSV) on autogenous grafted critical-sized cortical bone defects. Twenty-four rats were divided into 3 groups: Group C (control), RSV-0.1, and RSV-1. A 5-mm diameter critical-size defect was created in calvarium each animal. In C, filled by graft sterile saline–treated absorbable collagen sponge (ACS) applied. Defects experimental groups (groups RSV-0.1 RSV-1) ACS with saline solution...

Objectives: Bisphosphonate-related osteonecrosis of the jaw is potential side effect long-term bisphosphonate therapy. Different treatment modalities have been used in this and investigate effects low-level laser therapy (LLLT) extracorporeal shockwave (ESWT) on socket healing after tooth extraction rats given bisphosphonates. Methods: Forty male Wistar-Albino were experimental study. About 0.1 mg/kg zoledronic acid was administered intraperitoneally to all animals 3 times per week for 8...

Abstract Background Marriage satisfaction is one of the factors that affects life in healthy people and patients. In current literature, it found there a positive correlation between marriage satisfaction. Many such as sexual dysfunction, depression neurological disorders affect negatively satisfactions. However, not enough research dealing with how multiple sclerosis (MS) women's marital This study aimed to examine female patients MS (pwMS) relation dysfunction depression. A total 139...

Peripheral nerve injury is common and negatively affects an individual's quality of life. Drugs used for peripheral regeneration should aim to eliminate symptoms such as neuropathic pain have therapeutic effects. In recent studies, pigment epithelium-derived factor (PEDF) has been considered essential agent because its potential neuroprotective properties. this study, we aimed investigate the efficacy locally applied PEDF regeneration. Twenty-four Wistar albino male rats were used. The study...