A5003347743- Heavy Metal Exposure and Toxicity
- Alzheimer's disease research and treatments
- Advanced Drug Delivery Systems
- Mercury impact and mitigation studies
- Trace Elements in Health
- Advancements in Transdermal Drug Delivery
- Electrochemical Analysis and Applications
- Chromium effects and bioremediation
- Protein purification and stability
- Radiopharmaceutical Chemistry and Applications
- Advanced Nanomaterials in Catalysis
- Aluminum toxicity and tolerance in plants and animals
- Drug Solubulity and Delivery Systems
- Dermatology and Skin Diseases
- Gene expression and cancer classification
- Lipid Membrane Structure and Behavior
- Advanced Proteomics Techniques and Applications
- Allergic Rhinitis and Sensitization
- Parkinson's Disease Mechanisms and Treatments
- Neurological diseases and metabolism
- Inhalation and Respiratory Drug Delivery
- Nanoparticle-Based Drug Delivery
- Contact Dermatitis and Allergies
- Medical Imaging Techniques and Applications
- Nanoparticles: synthesis and applications
Banaras Hindu University
2022
Karolinska Institutet
2020-2021
JSS Academy of Higher Education and Research
2019-2020
Maastricht University
2019
Universitat Rovira i Virgili
2016-2018
Growing evidence suggest that Alzheimer’s disease (AD), the most common cause of dementia among elderly is a metabolic disorder associated with impaired brain insulin signaling. Hence, diabetic drug can be therapeutic option for management AD. The researches in this area are ongoing and Pioglitazone (PIO) one investigated Eventhough PIO treatment was found to improve AD significantly preclinical models, poor blood-brain barrier (BBB) permeability serious peripheral side effects limited its...
Relevant in vitro assays that can simulate exposure to nanoparticles (NPs) via inhalation are urgently needed. Presently, the most common method employed is expose lung cells under submerged conditions, but cellular responses NPs such conditions might differ from those observed at more physiological air-liquid interface (ALI). The aim of this study was investigate cytotoxic and inflammatory potential CeO2 (NM-212) a co-culture A549 epithelial differentiated THP-1 both ALI conditions....
Sensitization to a contact allergen brings with it lifelong risk develop allergic dermatitis. Inflammation is an important part of the skin sensitizing mechanism, and understanding how different haptens stimulate immune system, as well role played by cell types present in skin, may be helpful for developing optimized vitro models assessment new chemicals or mixtures. The aim this study was compare cytokine profile following exposure cells representing keratinocytes (HaCaT), monocytes (THP-1)...
Efavirenz (EFV) suffers from poor aqueous solubility which results in low bioavailability of the drug. Nanocarrier-based drug delivery systems offer a suitable alternative for improving physico-chemical properties and hence its efficacy. Nanosuspension (NS) EFV was formulated by solvent-anti solvent precipitation method using PVP K-30 as stabilizer sodium lauryl sulphate (SLS) wetting agent. Multi-level factorial design applied to select optimal formulation further characterized. The batch...