A5070145460- Nanoparticles: synthesis and applications
- Air Quality and Health Impacts
- Heavy Metal Exposure and Toxicity
- Heavy metals in environment
- Microplastics and Plastic Pollution
- Advanced Nanomaterials in Catalysis
- Healthcare and Environmental Waste Management
- Inhalation and Respiratory Drug Delivery
- Toxic Organic Pollutants Impact
- Noise Effects and Management
Stockholm University
2016-2020
Occupational exposure to airborne nickel is associated with an elevated risk for respiratory tract diseases including lung cancer. Therefore, the increased production of Ni-containing nanoparticles necessitates a thorough assessment their physical, chemical, as well toxicological properties. The aim this study was investigate and compare characteristics metal (Ni) oxide (NiO) particles focus on Ni release, reactive oxygen species (ROS) generation, cellular uptake, cytotoxicity genotoxicity....
Relevant in vitro assays that can simulate exposure to nanoparticles (NPs) via inhalation are urgently needed. Presently, the most common method employed is expose lung cells under submerged conditions, but cellular responses NPs such conditions might differ from those observed at more physiological air-liquid interface (ALI). The aim of this study was investigate cytotoxic and inflammatory potential CeO2 (NM-212) a co-culture A549 epithelial differentiated THP-1 both ALI conditions....
Abstract The use of refined toxicological methods is currently needed for characterizing the risks airborne nanoparticles (NPs) to human health. To mimic pulmonary exposure, we have developed an air–liquid interface (ALI) exposure system direct deposition NPs on lung cell cultures. Compared traditional submerged systems, this allows more realistic conditions effects induced by NPs. purpose study was investigate how silver (AgNPs) affected different ALI system. Additionally, viability and...
Abstract Studies using advanced toxicological methods enabling in vitro conditions that are more realistic currently needed for understanding the risks of pulmonary exposure to airborne nanoparticles. Owing carcinogenicity certain nickel compounds, increased production nanoparticles (Ni‐NPs) raises occupational safety concerns. The aim this study was investigate genotoxicity Ni‐NPs a recently developed air–liquid interface system. wild‐type Chinese hamster lung fibroblast cell line (V79)...
The European chemical framework REACH requires that hazards and risks posed by chemicals, including alloys metals, are identified proven safe for humans the environment. Therefore, differences in bioaccessibility terms of released metals synthetic biological fluids (different pH (1.5–7.4) composition) relevant different human exposure routes (inhalation, ingestion, dermal contact) have been assessed powder particles an alloy containing high levels nickel (Inconel 718, 57 wt% nickel). This is...