A5022182422- COVID-19 Clinical Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Long-Term Effects of COVID-19
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Cerebral Palsy and Movement Disorders
- Occupational Therapy Practice and Research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- CAR-T cell therapy research
- Infant Development and Preterm Care
- Respiratory Support and Mechanisms
- Family and Disability Support Research
- Venous Thromboembolism Diagnosis and Management
- Intensive Care Unit Cognitive Disorders
- Travel-related health issues
- Respiratory viral infections research
- Radiomics and Machine Learning in Medical Imaging
- Global Cancer Incidence and Screening
- Asthma and respiratory diseases
- Service-Learning and Community Engagement
- Indigenous Health, Education, and Rights
- Acute Myocardial Infarction Research
- Chronic Disease Management Strategies
- High Altitude and Hypoxia
Shrewsbury and Telford Hospital NHS Trust
2014-2024
Keele University
2023
University Hospitals Bristol NHS Foundation Trust
2023
University Hospitals Bristol and Weston NHS Foundation Trust
2023
The University of Queensland
2016-2023
Stanford University
2023
Princess Royal Hospital
2019-2020
Institute for Urban Indigenous Health
2017
University Hospitals of North Midlands NHS Trust
2015-2016
British Association for Immediate Care Scotland
2015
<h3>ABSTRACT</h3> A 40-year-old man developed acute brainstem dysfunction 3 days after hospital admission with symptoms of the novel SARS-CoV-2 infection (COVID-19). Magnetic resonance imaging showed changes in keeping inflammation and upper cervical cord, leading to a diagnosis rhombencephalitis. No other cause explained patient9s abnormal neurological findings. He was managed conservatively rapid spontaneous improvement some his signs discharged home continued neurology follow up.
BackgroundOutcomes are poor for patients with large B-cell lymphoma who relapse after CD19-directed chimeric antigen receptor (CAR) T-cell therapy (CAR19). CD22 is a nearly universally expressed surface and the efficacy of CD22-directed CAR (CAR22) in unknown, which was what we aimed to examine this study.MethodsIn single centre, open-label, dose-escalation phase 1 trial, intravenously administered CAR22 at two dose levels (1 million 3 CAR22-positive T cells per kg bodyweight) adult (aged...
Asylum seekers experience occupational deprivation in the context of restrictive social structures while awaiting refugee visa-status determination. How do citizenship status and policy shape asylum seekers' experiences? experiences Australia are examined using constructivist grounded theory. Field notes from 10 months weekly participant observation, 11 formal interviews, 34 survey responses four documents combined to identify a substantive theory - Structural-Personal Interaction (SPI). The...
People with chronic pain often have limited avenues for social support. Social isolation develops as their abilities to engage in daily and vocational activities decrease. With recent advancements technology increasing use of media, virtual platforms such blogging may provide opportunities This study analyzed published blog posts people investigate how support occurs through users the nature online interactions.A total 810 from January 2014 December 2015 on 44 publicly accessible blogs were...
Abstract Testifying in court is a daunting experience for any witness and an understanding of legal terminology can be beneficial. Previous research has found that children under 11 years have significant gaps their knowledge court. However, while older been to know more, misunderstandings warrant further investigation. This study was designed examine the understanding/misunderstanding key words by (aged between 12 15 years). Also, it predicted within current sample, participants from...
Background/aim Education on human rights will place occupational therapists in a strong position to address societal inequities that limit engagement for many client groups. The imminent changes the Minimum Standard of Occupational Therapists engender efforts towards social change and require university‐level education. This education might enhance profession's influence disadvantaging structures order effect change. To contribute evidence base therapy, this research aims understand...
Evidence suggests that participation in a Chronic Disease Self-Management (CDSM) program improves the health of clients. Many factors are known to influence these programs for broader Australian population. However, less is about why Aboriginal and Torres Strait Islanders choose participate. This study identifies key support or enable participate CDSM an urban setting.Twelve focus groups were undertaken with total 102 participants who diagnosed at risk chronic disease. These recruited from...
Interprofessional collaboration between clinicians, interpreters, and translators is crucial to providing care for consumers with limited English proficiency. training these professions has been overlooked outside of the medical field. This study investigated whether face-to-face speech pathologists, improved their knowledge, confidence, practice, attitudes engage in interprofessional collaboration. It also examined single-profession pathologists can produce similar outcomes when delivered...
<h3>ABSTRACT</h3> Why we only infrequently detect or report two more respiratory viruses co-infecting an adult host is poorly understood. We a rare case where influenza B and SARS-CoV-2 caused viral pneumonia in 74-year-old man diagnosed during the UK winter epidemic/pandemic for these organisms discuss concepts of co-infection.
Chemotherapy-associated cardiotoxicity is a common adverse event. Immune checkpoint inhibitors (ICI) – new class of monoclonal antibodies have revolutionized the management various diseases. Their use expected to increase in near future and their cardiac side effects been increasingly recognized.We describe case 67-year-old female patient with urothelial carcinoma undergoing treatment pembrolizumab who presented emergency department progressive fatigue, retrosternal pain palpitations for...
Refractory hypoglycaemia in a patient with solitary fibrous tumour (SFT) is very rare and was first reported 1930 independently by Doege Potter, leading to it being named 'Doege-Potter syndrome'. Here, we report the unusual case of 77-year-old woman giant pleural who presented complicating pulmonary hypertension associated heart failure hypoglycaemia, subsequently underwent curative resection mass clinical improvement.
Over recent decades research has confirmed the sensible belief that to participate in criminal proceedings (that were designed for adults) child witnesses may benefit from support and preparation. This is so even countries where special measures have been introduced make it less arduous children give their testimony (e.g. closed circuit television allow testify away actual courtroom; video recorded evidence-in-chief). Indeed, could be argued as more provide alleged victims or witnesses),...
As we approach the 10-year countdown to Sustainable Development Goals (SDGs), it is clear are far from achieving SDG 5 on gender equality, and 6 universal access water sanitation. While equality safe sanitation often treated as separate issues, they deeply linked interdependent. This paper argues that achieve both Goals, the international community must adopt more gender-transformative approaches development. Improved data collection at national sub-national levels needed; there also a...
Work It Out is a holistic chronic disease self-management program for urban Aboriginal and Torres Strait Islander people in Queensland, which part of an integrated comprehensive system care management. This study examines differences primary healthcare services use between participants non-participants. retrospective observational use, analysed data extracted from the clinical medical records assessments. General practitioner allied health were compared among non-participants using logistic...
ABSTRACTBackground Becoming a parent is significant occupational transition. Many contemporary approaches to infant care focus on algorithmic schedules and rigid routines for sleep feeding; delayed responses cues related feeding, sleep, cry-fuss communication; minimising sensory stimulation address sometimes highly medicalized unsettled behaviour via lenses of reflux, allergy, tongue-tie, often without supportive evidence-base or adequate assessment. Such interventions are at odds with...
Background: Patients with relapsed/refractory large B-cell lymphoma (LBCL) who progress after CD19 CAR T-cell therapy (CAR19) have poor outcomes. CD22 is expressed on the majority of lymphomas. Here, we report evaluation an autologous targeting (CAR22) for treatment adult patients R/R LBCL predominantly relapsed CAR19. Aims: The primary aims this trial assessed ability to successfully manufacture CAR22 and determine initial safety CAR22. Key secondary included overall response rate, complete...
Occupational justice research can generate knowledge about societal conditions that support participation in meaningful occupations. This is useful because occupational therapy's human rights goal to create are conducive engagement. Participants this field likely be vulnerable and need special ethical considerations. However, no model exists considerations for participants research.This study aimed develop a additional with participants.A secondary analysis was carried out on data from...
My body's getting healthy and my mind is with it.Considering Urban Aboriginal Torres Strait Islander Conceptions of Health.Drawing on the salutogenic, or 'origins health' framework, this article explores health well-being conceptions urban people identifies individual community health-enabling strategies employed to support their well-being.This qualitative study included 12 focus groups 83 predominantly Indigenous Australian participants Work It Out, a chronic disease self-management...