A5101783587- Mesenchymal stem cell research
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Immunodeficiency and Autoimmune Disorders
- Effects of Radiation Exposure
- Corneal Surgery and Treatments
- Gastric Cancer Management and Outcomes
- Cytomegalovirus and herpesvirus research
- Acute Myeloid Leukemia Research
- Ocular Surface and Contact Lens
- Prostate Cancer Treatment and Research
- Testicular diseases and treatments
- Skin Protection and Aging
- Neurogenesis and neuroplasticity mechanisms
- Multiple Myeloma Research and Treatments
- Helicobacter pylori-related gastroenterology studies
Harbin Medical University
2023
Children's Hospital of Fudan University
2022
North China University of Science and Technology
2021
Zhejiang University
2021
Shanghai Jiao Tong University
2019
XinHua Hospital
2019
Abstract Background Multiple myeloma (MM) is a major health concern. Understanding the different burden and tendency of MM in regions crucial for formulating specific local strategies. Therefore, we evaluated epidemiologic patterns explored risk factors death. Methods Data on were collected from 2019 Global Burden Disease study. We used incidence, mortality, disability adjusted life-years to estimate global, regional, national MM. Results In 2019, there 155,688 (95% UI, 136,585 – 172,577)...
To investigate the effects of mesenchymal stem cell-conditioned medium (MSC-CM) on radiation-induced oxidative stress, survival and apoptosis in hippocampal neurons.The following groups were defined: Control, radiation treatment (RT), RT+MSC-CM, MSC-CM, RT + N-Acetylcysteine (RT+NAC), MSC-CM PI3 K inhibitor (LY294002). A cell Counting Kit-8 (CCK-8) was used to measure proliferation. Apoptosis examined by AnnexinV/PI flow cytometric analyses. Intracellular reactive oxygen species (ROS)...
Stem cells play an important role in acute myeloid leukemia (AML). However, their precise effect on AML tumorigenesis and progression remains unclear.
To explore the protective effect of zeaxanthin on human limbal and conjunctival epithelial cells against UV-radiation excessive oxidative stress.Human were isolated from cadaver cultured in vitro. They challenged with UVB radiation H2O2 without pretreatment. Cell viability, p38 c-JUN NH(2)-terminal kinase (JNK) phosphorylation, IL-6, IL-8 MCP-1 secretion malondialdehyde (MDA) content measured.Zeaxanthin had no measurable cytotoxicity or when used at concentrations 5 µg/mL below. At 30 mJ/cm2...
Objective: To investigate the risk factors and outcomes of cytomegalovirus (CMV) infection post umbilical cord blood stem cell transplantation (UCBT) in children with primary immunodeficiency diseases (PID). Methods: Clinical data 143 PID who received UCBT Children's Hospital Fudan University from January 2015 to June 2020 were collected retrospectively. CMV-DNA plasma was surveilled once or twice a week within 100 days post-UCBT. According test results, divided into CMV-infected group...