- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Plant biochemistry and biosynthesis
- Mollusks and Parasites Studies
- Parasite Biology and Host Interactions
- Helminth infection and control
- Antioxidant Activity and Oxidative Stress
- Phytochemistry Medicinal Plant Applications
- Natural product bioactivities and synthesis
- Plant Growth Enhancement Techniques
- Insect Pest Control Strategies
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Phytochemistry and Biological Activities
- Wound Healing and Treatments
- Agricultural and Food Sciences
- Biological Activity of Diterpenoids and Biflavonoids
- Asymmetric Synthesis and Catalysis
- Chemical synthesis and alkaloids
- Cholesterol and Lipid Metabolism
- Carbohydrate Chemistry and Synthesis
- Plant chemical constituents analysis
- Composting and Vermicomposting Techniques
Universidade Federal Rural do Rio de Janeiro
2016-2025
Universidade Federal do Rio de Janeiro
1988-2023
Universidade Federal de Goiás
2012
Centro Universitário da Cidade
1993
ESPCI Paris
1991
Centre National de la Recherche Scientifique
1991
Abstract Knowledge of the structure-property-function relationship humic substances (HSs) is key for understanding their role in soil. Despite progress, studies on this topic are still under discussion. We analyzed 37 fractions with respect to isotopic composition, structural characteristics, and properties responsible stimulating plant root parameters. showed that regardless source origin carbon (C 3 or C 4 ), soil-extracted HSs acids (HAs) structurally similar each other. The more labile...
Sixty Brazilian honey samples were analysed for their total phenolic content with the Folin-Denis reagent, flavonoid by aluminium chloride method, and antioxidant activity reaction 2,2-diphenyl-1-picrylhydrazyl radical. Colour was also classified according to visual analysis Pfund scale. Linear relationships observed between colour content, phenolics capacity, contents. The white-coloured Citrus showed lowest activity, while light ambar Verbenaceae highest activity. Dark-coloured polyfloral...
Abstract: Various bioactive chemical constituents were quantified for 21 honey samples obtained at Rio de Janeiro and Minas Gerais, Brazil. To evaluate their antioxidant activity, 3 different methods used: the ferric reducing power, 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical‐scavenging 2,2′‐azinobis (3‐ethylbenzothiazolin)‐6‐sulfonate (ABTS) assays. Correlations between parameters statistically significant (−0.6684 ≤ r ≤−0.8410, P < 0.05). Principal component analysis showed that from...
The antioxidant activities and total polyphenolic content of five multifloral four orange blossom Brazilian honey samples their phenolic extracts were investigated. Identification quantification compounds carried out by HPLC-DAD (high-performance liquid chromatography with diode-array detection). radical scavenging activities, determined 2,2-diphenyl-1-picrylhydrazyl (DPPH•) expressed as EC50, ranged from 10.81 to 52.64 mg mL-1 for 6.17 52.87 the extracts. extract also...
Coumarin-β-ketoesters were used to synthesize new blue-fluorescent compounds exhibiting ICT. The Knoevenagel intermediate suggests that our Biginelli reaction passing by this mechanistic way is unlikely.
Thiosemicarbazone-acridine hybrids are prominent inhibitors of topoisomerases II. This study reports the design, synthesis, and antiproliferative evaluation eighteen new acridine–thiosemicarbazone derivatives as possible topoisomerase IIα. In general, compounds showed moderate to low cytotoxicity in first screening performed on three cell lines, with emphasis DT-3OCH3 series, which five six have been active. Further studies against resistant leukemic cells indicated an interesting profile...
A Candida albicans é um fungo oportunista da cavidade oral que provoca infecções em usuários de próteses (estomatite protética), pacientes debilitados (quimio ou radioterapia) e imunossuprimidos. Antimicrobianos como a anfotericina-B, nitrato micozadol, clorexidina, nistatina fluconazol são usados. Estes apresentam efeitos colaterais, principalmente com o uso frequente, alteração do paladar, pigmentação, náuseas, diminuição no apetite formação cepas resistentes. Os extratos própolis...
Este estudo investigou o efeito da adição de manjericão (Ocimum basilicum L.), orégano (Origanum vulgare) e salsa (Petroselinum crispum) no teor total carotenóides omeletes preparadas em air fryer, micro-ondas frigideira. Os extratos ervas foram inicialmente caracterizados por sua capacidade antioxidante teores fenólicos totais. As sem (controle) com as incorporadas à mistura clara ovo gema três níveis (0,25%, 0,5% 0,75%). Nas amostras controle, cozimento reduziu significativamente...
The work reported herein describes the synthesis and assessment of trypanocidal activity thirteen new 1,2,4-triazole-3-thiones obtained from natural piperine, main constituent dry fruits Piper nigrum. It is part a research program aiming to use abundant easily available products as starting materials for design molecules potentially useful antiparasitic drugs. variously substituted triazole derivatives were synthesized amide in four steps with microwave irradiation on overall yields ranging...
Abstract Background The use of humic substances as plant biostimulants has been increasingly attracting farmers and stunning researchers. ability these to enhance root growth by changing architecture is often linked their hormonal activities, such auxin effects nitric oxide production. Humeomics accesses the molecular constituents substances, revealing importance alkyl components because conformations chemical activities. Here, we describe alkamides present in acids compare bioactivities...
PROPOLIS.In this work were determined the total phenolic contents, antioxidant activity and chemical composition of twelve samples green propolis acquired from beekeepers other commercial extracts different regions Southeast Brazil.The contents evaluated by Folin-Ciocalteau DPPH, ABTS FRAP methods, respectively.Both types showed significant radical scavenging properties.HPLC-PDA was applied for quantification chlorogenic acid, caffeic ferulic para-coumaric rosmarinic vanillin, hesperidin,...
The glucose content in the hemolymph and glycogen digestive gland–gonad complex (DGG) cephalopedal mass of Biomphalaria glabrata exposed to different parasite doses (5 50 miracidia) Echinostoma paraensei as well activity lactate dehydrogenase were evaluated. HPLC (high-performance liquid chromatography) analyses also performed determine concentrations four organic acids (oxalic, succinic, pyruvic lactic) present infected uninfected snails, better understand effect infection on host's...
Curcumin (CUR) is the major constituent of rhizomes Curcuma longa and has been widely investigated for its chemotherapeutic properties. The well-known activity CUR against Leishmania sp., Trypanosoma brucei Plasmodium falciparum led us to investigate cruzi. In this work, we tested cytotoxic effects other natural curcuminoids on different forms T. cruzi, as well ultrastructural changes induced in epimastigote form parasite. was verified curcuminoid with more significant trypanocidal...
The antioxidant activities and polyphenolic levels of "assa peixe," "cambara," "morrão de candeia" Brazilian honeys were investigated.Phenolic extracts 11 evaluated spectrophotometrically to determine their total phenolic flavonoid contents, measured using DPPH, ABTS, FRAP assays.High-performance liquid chromatography coupled with diode array detection was applied the composition honey extracts.The presence fourteen compounds established (eleven acids three flavonoids), as well HMF abscisic...
This study evaluated the protective effect of ground aroeira (Schinus terebinthifolius Raddi) fruit addition against fatty acids and cholesterol oxidation in model systems containing sardine oil (Sardinella brasiliensis) during heating (150 180 °C). High temperatures reduced amount essential polyunsaturated caused formation oxidized products. Total oxides content increased from 58.9 ± 0.26 to 577.5 2.14 μg/g oil, after at °C. However, significantly protected lipids oxidation. Although...