A5073046872- Porphyrin and Phthalocyanine Chemistry
- Photodynamic Therapy Research Studies
- Photochromic and Fluorescence Chemistry
- Nanoplatforms for cancer theranostics
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Analytical Chemistry and Sensors
- Luminescence and Fluorescent Materials
- Conducting polymers and applications
- Advanced biosensing and bioanalysis techniques
- Gas Sensing Nanomaterials and Sensors
- Molecular Sensors and Ion Detection
- Synthesis of Organic Compounds
- Organic Electronics and Photovoltaics
- Flame retardant materials and properties
- Photochemistry and Electron Transfer Studies
- TiO2 Photocatalysis and Solar Cells
- Electrochemical sensors and biosensors
- Liquid Crystal Research Advancements
- Metal complexes synthesis and properties
- Synthesis and biological activity
- Organic Chemistry Cycloaddition Reactions
- Click Chemistry and Applications
- Corrosion Behavior and Inhibition
- Synthesis and Reactivity of Sulfur-Containing Compounds
Gebze Technical University
2015-2024
Kocaeli Üniversitesi
2015-2016
Three Zn(II) phthalocyanines substituted by hydroxyl-terminated tetraethylene glycol chains have been synthesized. In order to evaluate the potential of these highly water-soluble as type II-photosensitisers for photodynamic therapy, their structure–activity relationship was assessed determining relevant photophysical and photochemical properties, such aggregation behaviour in aqueous buffers, fluorescence properties efficiency with regard generation singlet oxygen. addition, evidence a...
Four isomerically pure octasubstituted zinc phthalocyanines with variations in the attachment atom and positions of substituents were selected for a systematic investigation effect substitution pattern on their electronic spectroscopic properties. Effects which investigated are position, electron donating withdrawing properties, force substituent. The results discussed interpreted based theoretical experimental determination orbital levels. This work allows us to highlight patterns most...
Phthalocyanines (Pcs) are organic compounds able to act as chemical recognition systems because of the various physical effects induced in them by interaction with a large number gases. The gas response, stability and other sensing characteristics Pc films affected many factors, such film morphology, molecular orientation so on. between coatings molecules may be classified terms irreversible affinity, reversible (usually charge transfer) reaction or sorption. nature interactions coating...
Photodynamic therapy (PDT) and vascular-disrupting agents (VDA) each have their advantages in the treatment of solid tumors, but also present drawbacks. In PDT, hypoxia at center tumor limits conversion molecular oxygen into singlet oxygen, while VDAs are deficient affecting rim tumor. A phthalocyanine-chalcone conjugate combining VDA properties chalcones with PDT phthalocyanines was designed to address these deficiencies. Its vascular targeting, photophysical, photochemical, photodynamic...
The palliative treatment options for advanced hepatocellular carcinoma (HCC) are currently not satisfying. use of photodynamic therapy (PDT) has gained much attention in the several cancers and been approved as an alternative approach treating different forms cancers. We investigated first time PDT effects tetra-triethyleneoxysulfonyl zinc phthalocyanine (ZnPc) on HCC cells. Photoactivation ZnPc loaded cells resulted a dose- time- dependent growth inhibitory effect, production reactive...
A novel push–pull zinc phthalocyanine dye (KH1) containing 2,6-di- tert -butyl-4-methylphenoxy donor groups was synthesized for DSSCs. The DSSC based on the exhibited a PCE of 3.12%.
The synthesis, photophysical and photochemical properties of the tetra- octa-poly(oxyethylene)substituted zinc (II) phthalocyanines are reported for first time. new compounds have been characterized by elemental analysis, IR, 1H 13C NMR spectroscopy, electronic spectroscopy mass spectra. General trends described photodegradation, singlet oxygen, triplet state fluorescence quantum yields, lifetimes these in dimethylsulfoxide (DMSO). Photophysical phthalocyanine complexes very useful PDT...
In this study, we synthesized and characterized a silicon phthalocyanine substituted with 3-hydroxypyridin-2-thione (SiPc-HDACi), designed to be chemophotodynamic therapy agent acting as histone deacetylase inhibitor, determined its photophysical, photochemical, photobiological properties. Next, evaluated anticancer efficacy on MCF-7, double positive MDA-MB-231, triple negative breast cancer cell lines, well healthy human endothelial line (HUVEC). Our results indicate that SiPc-HDACi can...
The five possible non-peripherally substituted zinc(II) phthalocyanines with different molecular symmetries (Pc1–Pc5) were synthesized from statistical condensation of the phthalonitrile derivatives (A and B). 2-[2-(2-ethoxyethoxy)ethoxy]-1-[2-((2-ethoxyethoxy)-ethoxy)ethoxymethyl]ethyloxy 2′-[(tert-butoxycarbonyl)amino]ethoxy groups used as substituents. structures new compounds characterized using elemental analysis spectroscopic data including IR, 1 H 13 C NMR, electronic absorption mass...