A5101885768- Plant Ecology and Soil Science
- Drug Transport and Resistance Mechanisms
- Lipid metabolism and disorders
- Cancer Treatment and Pharmacology
- Pharmacological Effects of Natural Compounds
- Mast cells and histamine
- Natural product bioactivities and synthesis
- Chronic Myeloid Leukemia Treatments
- Phytochemical compounds biological activities
- Central Venous Catheters and Hemodialysis
- Dialysis and Renal Disease Management
- Hemodynamic Monitoring and Therapy
- Gastrointestinal Tumor Research and Treatment
- Neurological Disease Mechanisms and Treatments
- Medicinal Plant Pharmacodynamics Research
- Pharmacogenetics and Drug Metabolism
- Fungal Biology and Applications
Sichuan University
2019
West China Hospital of Sichuan University
2019
Pfizer (China)
2018
Chinese Academy of Medical Sciences & Peking Union Medical College
2011
Melanomas harbor aberrations in the c-Kit gene. We tested efficiency of tyrosine kinase inhibitor imatinib selected patients with metastatic melanoma harboring mutations or amplifications.Forty-three were enrolled on this phase II trial. Each patient received a continuous dose 400 mg/d unless intolerable toxicities disease progression occurred. Fifteen who experienced allowed to escalate 800 mg/d.Forty-three eligible for evaluation, and median follow-up time was 12.0 months. The...