Weiwei Wang

ORCID: 0000-0001-9059-3265
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About
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Research Areas
  • Water Quality and Pollution Assessment
  • Hydrology and Watershed Management Studies
  • Soil and Water Nutrient Dynamics
  • Water Resources and Sustainability
  • Groundwater and Isotope Geochemistry
  • RNA Interference and Gene Delivery
  • Cytokine Signaling Pathways and Interactions
  • Endoplasmic Reticulum Stress and Disease
  • S100 Proteins and Annexins
  • RNA regulation and disease
  • RNA Research and Splicing

First Affiliated Hospital of Zhengzhou University
2024-2025

North China University of Water Resources and Electric Power
2024

Xinjiang University
2022-2023

Resistance to temozolomide (TMZ) remains is an important cause of treatment failure in patients with glioblastoma multiforme (GBM). ADAR1, as a member the ADAR family, plays role cancer progression and chemotherapy resistance. However, mechanism by which ADAR1 regulates GBM TMZ resistance still unclear. We first constructed stable transfected strains was knocked down overexpressed investigate effect on first-line glioma drug TMZ. Subsequently, we validated that induces autophagy activation...

10.1111/cns.70168 article EN cc-by CNS Neuroscience & Therapeutics 2025-01-01

Water security, as a crucial component of national plays significant role in maintaining regional stability and ensuring the healthy rapid development economy society. The Yellow River water-receiving area Henan Province (YRWAR-HN) is selected research this study. Firstly, comprehensive evaluation index system constructed based on actual water security problems area, single quantification–multiple indices syntheses–poly-criteria integration method (SMI-P) introduced to quantify degree 14...

10.3390/w16172497 article EN Water 2024-09-03

Understanding of the buffer scale effect on water quality changes analysis in arid and humid regions is great significance for exploring best pollution scientific planning land use. The objective this study to determine optimal scales (500, 1000, 1500, 2000, 2500 3000 m) use that affect ammonia nitrogen (NH3-N) total phosphorus (TP) Jing-Bortala River Watershed (JBRW) (arid region) Liyang Region (LR) (humid under a site buffer. PLS-SEM was used fit pathway relationships between influencing...

10.1016/j.ecolind.2022.109546 article EN cc-by-nc-nd Ecological Indicators 2022-10-12

Abstract Aims Although radiotherapy is a core treatment modality for various human cancers, including glioblastoma multiforme (GBM), its clinical effects are often limited by radioresistance. The specific molecular mechanisms underlying radioresistance largely unknown, and the reduction of an unresolved challenge in GBM research. Methods We analyzed verified expression nuclear autoantigenic sperm protein (NASP) gliomas relationship with patient prognosis. also explored function NASP cell...

10.1111/cns.14709 article EN cc-by CNS Neuroscience & Therapeutics 2024-04-01

艾比湖流域是西北地区重要的生态屏障,维持着该地区乃至整个新疆北部的生态平衡.艾比湖流域水环境的好坏关系着当地经济和流域的可持续发展.然而,针对艾比湖流域长期水质变化、营养状况和健康风险的研究较少,故基于艾比湖流域2005—2020年12个断面长时间序列的监测数据,利用加拿大水质指数(Canadian water quality index,CWQI)评价河湖水质状况,采用综合营养状态指数(comprehensive trophic level index,TLI (∑))评价艾比湖水体富营养化状态,使用Risk评价水环境健康风险(water environment healthy...

10.18307/2022.0210 article EN Journal of Lake Sciences 2022-01-01
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