Xiujin Chen

ORCID: 0000-0001-9063-7221
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Advanced Nanomaterials in Catalysis
  • Biosensors and Analytical Detection
  • Nanocluster Synthesis and Applications
  • Electrochemical sensors and biosensors
  • Carbon and Quantum Dots Applications
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Nanoplatforms for cancer theranostics
  • CRISPR and Genetic Engineering
  • Analytical chemistry methods development
  • Plant Pathogenic Bacteria Studies
  • Plant Pathogens and Fungal Diseases
  • Essential Oils and Antimicrobial Activity

Henan University of Science and Technology
2022-2025

Soaked Auricularia auricula-judae serves as a significant vehicle for foodbome disease caused by Burkholderia gladiol. This study aimed to develop predictive models assessing the growth of B. gladioli and its bongkrekic acid (BA) toxin production in soaked auricula-judae. The experiment involved inoculations with incubating it at 4, 10, 15, 20, 26, 30 36 °C. Data on concentration was fitted using Origin IPMP 2013 software establish model, while BA were measured create model. Model validation...

10.2139/ssrn.5092785 preprint EN 2025-01-01

Sensitive detection of ochratoxin A (OTA) is significant and essential because OTA may pose risks to human animal health. Here, we developed an electrochemical aptasensor for analysis using polyamidoamine (PAMAM) dendrimers as a signal amplifier. As carrier, PAMAM has numerous primary amino groups that can be coupled with thiolated complementary strand DNA (cDNA), allowing it recognize aptamers bound the surface horseradish peroxidase (HRP)-modified gold nanoparticles (AuNPs), thereby...

10.3390/bios13110955 article EN cc-by Biosensors 2023-10-26

The aptasensors have received extensive attention and been widely used in various targets, however, the development of aptamer based LFA (Apt-LFA) is still far behind, especially for small molecule targets detection. shortcoming long response time severely hindered Apt-LFA strip application on-site detection molecules contaminants environment foods. Herein, we introduce bivalent triple helix (BTHA) nanozyme yielding an accelerated signal amplified acetamiprid We obtained a BTHA with two 10...

10.2139/ssrn.4259909 article EN SSRN Electronic Journal 2022-01-01

CRISPR/Cas holds great promise for biosensing applications, however, restricted to nucleic acid targets. Here, we broaden the sensing target of small molecules via integrating a bivalent aptamer as recognition component. Using adenosine 5-triphosphate (ATP) model molecule, found that selected could shorten binding time between and ATP from 30 min 3 min, thus dramatically accelerating detection ATP. To facilitate on-site detection, integrated lateral flow assay (LFA) with strategy (termed...

10.2139/ssrn.4167982 article EN SSRN Electronic Journal 2022-01-01

Indicator replacement assay combining with fluorescence resonance energy transfer(FRET) effect has attractive performance in sensing small molecules, however, there wasn’t application pesticide molecule reported so far. In this work, we prepared a nanocomplex (NCP), AuAgNCs-CD, through self-assembly of gold nanoclusters (AuNCs), silver (AgNCs) and carboxymethyl-β-cyclodextrin (CM-β-CD) by one-step method. The AuAgNCs-CD NCP not only demonstrated enhanced emission, but also could encapsulate...

10.2139/ssrn.4372827 article EN 2023-01-01

Nanomaterial based indicator displacement assays (IDA) have demonstrated some interesting applications in chemosensing, however, restricted to the fluorescence quenching by nanomaterials. Fluorescent metal nanocluster (NCs), serving as a receptor and producing dual signal responses IDA, may provide new sensing paradigms applications. In this work, we utilized GSH/CD-AuNCs KAE/Al 3+ complex indicator. Due inner filter effect (IFE) photoinduced electron transfer (PET) effect, of was greatly...

10.2139/ssrn.4225346 article EN SSRN Electronic Journal 2022-01-01
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