A5100627118- Influenza Virus Research Studies
- COVID-19 epidemiological studies
- RNA and protein synthesis mechanisms
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Digital Games and Media
- Escherichia coli research studies
- Trypanosoma species research and implications
- Bat Biology and Ecology Studies
- Impact of Technology on Adolescents
- Vaccine Coverage and Hesitancy
- interferon and immune responses
- Monoclonal and Polyclonal Antibodies Research
- Media Influence and Health
Fujian Medical University
2024
University of Illinois Urbana-Champaign
2021-2024
Electronic sports (esports) has become a practical intervention for young people craving social connections since the COVID-19 pandemic. Past studies have shown an equivocal role of esports participation in boosting ties or connectedness. It is unclear if their relationship affected by subjective attitudes gamers. Moreover, present pandemic may further modify this to greater extent.
ABSTRACT The dynamics of SARS-CoV-2 replication and shedding in humans remain poorly understood. We captured the infectious virus viral RNA during acute infection through daily longitudinal sampling 60 individuals for up to 14 days. By fitting mechanistic models, we directly estimate reproduction clearance rates, overall infectiousness each individual. Significant person-to-person variation suggests that individual-level heterogeneity contributes superspreading. Viral genome load often...
The antigenic evolution of the influenza A virus hemagglutinin (HA) gene poses a major challenge for development vaccines capable eliciting long-term protection. Prior efforts to understand mechanisms that govern viral mainly focus on HA in isolation, ignoring fact must act concert with neuraminidase (NA) during replication and spread. Numerous studies have demonstrated degree which receptor-binding avidity receptor-cleaving activity NA are balanced each other influences overall fitness. We...
Abstract The ongoing antigenic evolution of the influenza A virus (IAV) hemagglutinin (HA) gene limits efforts to effectively control spread in human population through vaccination. factors that influence and constrain evolutionary potential HA remain poorly understood. Efforts understand mechanisms govern typically examine isolation ignore importance balancing receptor-binding activities with receptor-destroying viral neuraminidase (NA) for maintaining fitness. We hypothesized need maintain...
ABSTRACT The antigenic evolution of the influenza A virus hemagglutinin (HA) gene poses a major challenge for development vaccines capable eliciting long-term protection. Prior efforts to understand mechanisms that govern viral mainly focus on HA in isolation, ignoring fact must act concert with neuraminidase (NA) during replication and spread. Numerous studies have demonstrated degree which receptor binding avidity cleaving activity NA are balanced each other influences overall fitness. We...