A5005985586- Research Data Management Practices
- Scientific Computing and Data Management
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Virtual Reality Applications and Impacts
- Composting and Vermicomposting Techniques
- COVID-19 epidemiological studies
- Distributed and Parallel Computing Systems
- Advanced Data Storage Technologies
- Forest Insect Ecology and Management
- Biosensors and Analytical Detection
- Impact of Technology on Adolescents
- Software System Performance and Reliability
- Fungal Biology and Applications
- Media Influence and Health
- Renal cell carcinoma treatment
- Irrigation Practices and Water Management
- scientometrics and bibliometrics research
- Digital and Traditional Archives Management
- Drug-Induced Ocular Toxicity
- Online and Blended Learning
- Cancer, Hypoxia, and Metabolism
- Food Allergy and Anaphylaxis Research
- Melanoma and MAPK Pathways
- Hepatocellular Carcinoma Treatment and Prognosis
OSE Immunotherapeutics (France)
2024
University of Illinois Urbana-Champaign
2017-2023
National Center for Supercomputing Applications
2017-2023
University of Illinois System
2022
Astex Pharmaceuticals
2021
National Center for Supercomputing Applications
2018
Florida Gulf Coast University
2011-2013
Queen Elizabeth II Health Sciences Centre
2013
Serial screening is critical for restricting spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by facilitating timely identification infected individuals to interrupt transmission. Variation in sensitivity different diagnostic tests at stages infection has not been well documented.In a longitudinal study 43 adults newly with SARS-CoV-2, all provided daily saliva and nasal swabs quantitative reverse transcription polymerase chain reaction (RT-qPCR), Quidel SARS Sofia...
ABSTRACT The dynamics of SARS-CoV-2 replication and shedding in humans remain poorly understood. We captured the infectious virus viral RNA during acute infection through daily longitudinal sampling 60 individuals for up to 14 days. By fitting mechanistic models, we directly estimate reproduction clearance rates, overall infectiousness each individual. Significant person-to-person variation suggests that individual-level heterogeneity contributes superspreading. Viral genome load often...
Diagnostic tests and sample types for SARS-CoV-2 vary in sensitivity across the infection period. We show that both RTqPCR (from nasal swab saliva) Quidel SARS Sofia FIA rapid antigen peak during period which live virus can be detected swabs, but of rises more rapidly pre-infectious also use empirical data to estimate sensitivities as a function testing frequency. will effective than at identifying infected individuals prior or early infectious thus minimizing forward transmission (provided...
<p>Due to the unique applications of virtual reality in many modern contexts, Second Life (SL) offers inimitable opportunities for research and exploration experiential learning as part a distance curriculum assignment. A review current regarding SL examined real world social influences online interactions what effects on users may be. This aids students understanding constructionist perceptions worldview those persons they serve services. suggests importance developing an relationship...
Due to the unique applications of virtual reality in many modern contexts, Second Life (SL) offers inimitable opportunities for research and exploration. A review current regarding SL has examined influence real world social influences online interactions what effects on users may be. This suggests importance developing an understanding relationship between users’ life their Life, how two are related. Some begun reveal effectiveness telecommunication computer simulation with certain clients...
von Hippel-Lindau (VHL) disease is an autosomal dominant condition characterized by the development of benign and malignant tumours, including cases renal cell carcinoma (RCC). Early detection RCC through routine surveillance can lead to decreased morbidity mortality. Data on number patients in Nova Scotia (NS) who have VHL disease, manifestations frequency mode not previously been collected or reported. This project was designed obtain that information.The management with determined...
Brown Dog is a data transformation service for auto-curation of long-tail data. In this digital age, we have more available analysis than ever and trend will only increase. According to most estimates, 70--80% unstructured, together with unsupported formats inaccessible software tools, in essence, not either easily accessible or usable its owners meaningful way. aims at making by indexing, leveraging existing novel tools. paper, discuss the recent major component improvements including tools...
The future for science gateways warrants exploration as we consider the possibilities that extend well beyond ’science’ and high-performance computing into new interfaces, applications user communities. In this paper, look retrospectively at successes of representative thus far. This serves to highlight existing gaps need overcome in areas such accessibility, usability interoperability, broader outreach by drawing insights from technology adoption research. We explore two particularly...
When hydrologic scientists are looking for data to use in their models relevant research area, they encounter a bottleneck when trying collect information, sometimes might not know of all the available sources. Great Lakes Monitoring (GLM) collects from 5 different state and federal agencies that take measurements on nutrients, geochemicals, contaminants, among other water quality directly affect health Lakes. In this paper, we describe cyberinfrastructure has been implemented order address...
Second Life (SL) offers unique opportunities for research and exploration in virtual environments. A review of current regarding SL has examined the influence real world social influences online interactions what effects on users may be. This suggests importance developing an understanding relationship between users' life (RL) their SL. Some begun to reveal effectiveness telecommunication computer simulation with certain clients fields mental health human services, yet there is a lack...
No abstract available.
The emerging transdiscipline of Computational Archival Science (CAS) links frameworks such as Brown Dog and repository software Digital Repository At Scale To Invite Computation (DRAS-TIC) to yield an understanding working with digital collections at scale for cultural data. DRAS-TIC projects here serve the basis expandable distributed storage/service architecture on-demand, horizontally scalable integrated preservation analysis services.
<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Researchers and educators in humanities such as computational linguists, digital humanists, those doing historical reconstructions are increasingly heavy users of and/or data resources. Many know about activities, working groups, initiatives around the FAIR (Findable, Accessible, Interoperable, Reusable) principles a driving force for improving sharing software. However, it seems researchers...
We present an open source extensible web framework for the analysis of different farm practices and programs easy dissemination their results to users. Currently, this is being applied two use cases --- a web-based decision support system cover crop management program tool assist farmers, academics, policymakers understand policies surrounding Farm Bill. Through first case, we address problem bridging gap between scientific research that happens in labs experimental plots day decisions taken...
Abstract Background: The RAS-RAF-MEK-ERK pathway is commonly upregulated in human cancers. This an open-label Phase 1 study of ASTX029, a dual-mechanism extracellular signal-regulated kinase 1/2 (ERK1/2) inhibitor, subjects with relapsed/refractory solid tumors (NCT03520075). Methods: primary objectives are to identify maximum tolerated dose and/or recommended 2 dose. ASTX029 was administered orally daily 21-day cycles as powder-in-bottle (PiB, Cohort 1/10mg) and tablet formulation...