Diabetic nephropathy (DN) is a serious complication of diabetes associated with increased risk mortality, and cardiovascular renal outcomes. Diagnostic markers to detect DN at early stage are important as intervention can slow loss kidney function improve patient Urinary biomarkers may be elevated in diabetic patients even before the appearance microalbuminuria, used useful marker for detecting normoalbuminuria (early DN). We reviewed some new urinary biomarkers, such as: Neutrophil...

The aim of this study was to determine the status glycemic control and identify factors associated with poor among diabetic out-patients.A hospital based cross-sectional conducted randomly selected 384 (126 type 1 258 2) adults attending a in Northeast Ethiopia from January April 30, 2017. Of total participants, 70.8% had (defined as mean fasting blood glucose level above 130 mg/dl). In multivariate analysis, rural residence (AOR = 2.61, 95% CI 1.37-4.96), low educational 7.10, 2.94-17.17)...

Background Health care professionals, especially medical students, are at greater risk of contracting hepatitis B and C virus infections due to their occupational exposure percutaneous injuries other body fluids. The aim this study was determine the seroprevalence among medicine health science students in Northeast Ethiopia assess knowledge practice towards viral hepatitis. Methods A cross-sectional conducted a total 408 during period from March September 2017. pre-coded self-administered...

With prolonged survival and aging of persons with HIV on combination antiretroviral therapy (ART), hypertension has emerged as a significant cause morbidity mortality globally. However, little is known about the burden this comorbid condition among adults living in sub-Saharan Africa. In study, we aimed to determine prevalence factors associated HIV-infected patients receiving ART Northeast Ethiopia.A cross-sectional study was conducted at clinic Dessie Referral Hospital, Ethiopia, between...

Diabetes mellitus (DM) is a chronic condition associated with raised levels of blood glucose due to the body cannot produce any or enough insulin hormone be effectively utilized produced by body. Patients poorly controlled diabetes show significant alteration in various parameters including metabolic, cellular, immunological, and hematological disturbances that leads vascular complications. Thus, main aim this study compare between type 2 (T2DM) patients healthy controls.A comparative...

Background: Chronic kidney disease (CKD) in diabetes is associated with an increased risk of premature mortality, failure and cardiovascular disease. No studies are available on the prevalence CKD among diabetics Ethiopia. The aim this study was to determine its factors diabetic adults attending Butajira hospital Southern Ethiopia based estimated glomerular filtration rate (GFR). Methods: A facility cross sectional conducted hospital, southern 214 randomly selected adults. Demographic,...

Diabetic patients with chronic kidney disease (CKD), as defined by a reduced glomerular filtration rate (GFR), are at greater risk for cardiovascular and renal events mortality. The aim of this study was to determine the prevalence CKD among diabetic attending hospital in southern Ethiopia, assess underdiagnosis insufficiency those normal serum creatinine. A total 214 randomly selected diabetics follow-up clinic Butajira Ethiopia participated during period from September 1 October 31, 2013....

Background. Thrombocytopenia is the most common hematological abnormality in patients with acute malaria. This study aimed to determine role of thrombocytopenia as a diagnostic marker for malaria febrile illness. Method. A cross-sectional health facility-based was conducted on 423 consecutively selected at Ataye District Hospital from February May 2019 GC. complete blood count and microscopy were performed each patient. ROC curve analysis calculate sensitivity, specificity, positive...

Background Data on the burden of dyslipidaemia among people with HIV undergoing antiretroviral therapy (ART) in sub-Saharan Africa are limited and little is known about factors contributing for poor lipid profiles. The aim this study was to determine prevalence associated levels HIV-infected patients receiving first-line combination ART North Shewa, Ethiopia. Methods A cross-sectional conducted between April December 2018 392 adults at least six months clinic Mehal Meda Hospital Blood...

Abstract In the last two decades, there have been increasing recognition of excess cases end-stage renal disease (ESRD) requiring replacement therapy without common underlying causes (diabetes, hypertension, glomerulonephritis, or any identifiable cause) in many parts low-to-middle income countries. ESRD unknown etiology mainly affects young working-age adults and is a global health problem with substantial morbidity, mortality disability. this review, we provide comprehensive overview...

The aim of this study was to estimate the prevalence renal insufficiency using estimated glomerular filtration rate (eGFR) among adult outpatients with normal SCr.A total 414 patients SCr were included in study. Mean GFR (ml/min/1.73 m2) 116.8 ± 43.5 MDRD equation and 90.5 33.1 by C-G formula. According formula, mild (i.e. eGFR 60-89.9 ml/min/1.73 found 21.5% moderate 30-59.9 7.7%. Cockcroft-Gault (C-G) 38.2% 16.9% SCr. In multivariate analysis, older age, female sex, a family history kidney...

The aim of this study was to determine the prevalence diabetes mellitus and its associated factors among human immunodeficiency virus-infected patients on anti-retroviral therapy in Northeast Ethiopia.A facility based cross-sectional conducted 408 HIV-infected adults (≥ 18 years old) attending an ART clinic Ethiopia from January March 30, 2018. mean (± SD) age studied 37 ± 10.3 years, 273 (66.9%) were female. Of total participants, 36 (8.8%, 95% CI 6.4% 11.8%) had 61 (15.0%, 11.5% 18.6%)...

CD4+ cell count recovery after effective antiretroviral therapy (ART) is an important determinant of both AIDS and non-AIDS morbidity mortality. Data on initiation ART are still limited in Sub-Saharan Africa. The aim this study was to assess among HIV-infected adults initiating Ethiopian setting.A retrospective cohort between September 2008 June 2019 carried out. defined as increase >100 cells/mm3 from baseline or achievement a >500 at 12 months initiation. Factors associated with were...

Background Anemia is a common finding in patients with diabetes, even the absence of kidney disease and risk factor for adverse outcomes, including all-cause cardiovascular mortality. Despite this, relatively little known about burden anemia among adults diabetes sub-Saharan Africa. The aim this study was to determine prevalence its association renal diabetic adult outpatients attending hospital Northeast Ethiopia. Methods A cross-sectional conducted 412 at clinic Dessie Referral Ethiopia,...

Abstract Background Chronic kidney disease (CKD) is a serious complication of diabetes associated with adverse outcomes renal failure, cardiovascular and mortality. Despite this, data regarding the burden awareness CKD among adults in Sub-Saharan Africa countries are lacking. The aim this study was, therefore to determine prevalence diabetic outpatients attending hospital Northeast Ethiopia. Methods We conducted cross-sectional on 323 at clinic Ethiopia, from February 1 July 30, 2016. Each...

Anemia is a strong predictor of mortality and poor quality life among persons with either renal impairment or HIV infection. In this study, we investigated the prevalence anemia its association insufficiency infected patients initiating ART at hospital in Northeast Ethiopia. retrospective cohort records 373 on were selected Dessie Referral hospital, South Wollo, Ethiopia from September 2010 to August 2013. Socio-demographic clinical characteristics study collected using standardized data...

Aim To evaluate the prevalence and associated factors of abnormal renal function among Ethiopian HIV-infected patients at baseline prior to initiation antiretroviral therapy (ART) during follow-up. Methods We conducted a retrospective observational cohort study HIV infected who initiated ART outpatient clinic Mehal Meda Hospital North Shewa, Ethiopia from January 2012 August 2018. Demographic clinical data were abstracted medical records patients. Renal was assessed by estimated glomerular...

Background Chronic kidney disease (CKD) is increasingly common in hospitalized patients and associated with increased risk for in-hospital morbidity mortality. However, data regarding the prevalence of CKD African patient population are limited. We therefore examined factors impaired renal function albuminuria among adult admitted to internal medicine wards a hospital Northeast Ethiopia. Methods A cross-sectional study was conducted from January 1 April 30, 2020 at inpatient settings Dessie...

Background: Anemia is the most common hematologic abnormality in HIV patients and associated with disease progression decreased survival. This study aims to describe prevalence predictors of anemia positive at time ART initiation public health facilities Arba Minch town, Southern Ethiopia. Methods: A total 411 adults (?15 years) complete information on hemoglobin levels CD4 count clinical characteristics registered from 2006 2013 were assessed for risk factors clinic hospital center. The...

Cytopenias affect the outcomes of highly active anti-retroviral therapy that results in higher morbidity, mortality, and impaired quality life. The purpose this study was to assess prevalence cytopenia its associated factors among HIV infected adults on antiretroviral at Mehal Meda Hospital, North Shewa Zone, Ethiopia.A cross-sectional health facility based conducted 499 consecutively selected adult patients taking HAART for least six months from January April 2018. participant's...