- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- Antibiotic Use and Resistance
- HIV Research and Treatment
- Bacterial Infections and Vaccines
- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- Immune responses and vaccinations
- SARS-CoV-2 and COVID-19 Research
- Mosquito-borne diseases and control
- Drug-Induced Hepatotoxicity and Protection
- Diabetes Management and Research
- Drug Transport and Resistance Mechanisms
- Thyroid Cancer Diagnosis and Treatment
- Iron Metabolism and Disorders
- HIV-related health complications and treatments
- COVID-19 Impact on Reproduction
- Malaria Research and Control
- Reproductive tract infections research
- Lipoproteins and Cardiovascular Health
- Hemoglobinopathies and Related Disorders
- Streptococcal Infections and Treatments
- Blood Pressure and Hypertension Studies
- Vibrio bacteria research studies
- Respiratory viral infections research
Wollo University
2021-2024
Malaria is among the leading causes of mortality and morbidity under five children in developing countries. Ethiopia has set targets for controlling eliminating malaria through at-risk group interventions. However, disease remains a serious public health concern endemic areas like Wollo, Northeast Ethiopia. Therefore, this study aimed to determine prevalence, risk factors parasite density Ziquala district.A facility-based cross-sectional was conducted hospital, Tsitsika, Mishra Hamusit...
CD4+ cell count recovery after effective antiretroviral therapy (ART) is an important determinant of both AIDS and non-AIDS morbidity mortality. Data on initiation ART are still limited in Sub-Saharan Africa. The aim this study was to assess among HIV-infected adults initiating Ethiopian setting.A retrospective cohort between September 2008 June 2019 carried out. defined as increase >100 cells/mm3 from baseline or achievement a >500 at 12 months initiation. Factors associated with were...
Carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) are usually healthcare associated. The aim of this study was to investigate the epidemiology hospital-acquired CRE and multi-drug-resistant infections, identify associated risk factors in hospitalized patients Northeast Ethiopia.This cross-sectional conducted admitted with sepsis between January June 2021. Demographic clinical data were collected using questionnaires. In total, 384 samples cultured based on source...
Background Hematological reference intervals (RIs) are affected by inherent variables like age, sex, genetic background, environment, diet and certain circumstances such as pregnancy signifying the need for population specific values. This study was designed to establish RIs common hematological parameters of apparently healthy pregnant non-pregnant women from Northeast Ethiopia. Method community based cross-sectional recruited 600 in South Wollo Zone, Ethiopia June August 2019. Complete...
Background: T1DM is a chronic organ-specific T-cell-mediated autoimmune disease characterized by the selective destruction of β-cells in islets Langerhans, resulting insulin deficiency and hyperglycemia. Genes for cytotoxic T lymphocyte-associated antigen 4 have been hypothesized as possible contender genes vulnerability. However, it has not studied Ethiopian population yet. Objective: The aim study was to investigate CTLA-4 exon 1 linked A49G polymorphism with its biological features among...
Background Urinary tract infections are common bacterial and fungal in humans, occurring both the community immunocompromised patients healthcare settings. have a significant health impact on HIV-infected patients. Nowadays, drug-resistant pathogens widespread poses serious clinical risk, causes urinary infection. The agents of bacteria fungi that cause infection Escherichia coli followed by Klebsiella pneumonia , Staphylococcus saprophyticus Enterococcus faecalis group B streptococcus...
Background: Streptococcus pneumoniae infection is still the world's most serious public health problem among children under age of five. Nasopharyngeal carriage rate has been identified as an important risk factor for acquisition community acquired respiratory tract infection. To date, little known about nasopharyngeal and antimicrobial susceptibility pattern preschool in Ethiopia. Objective: The aim this study was to assess prevalence children. Methods: A cross-sectional conducted from...
One of the major risk factors for cardiovascular disease is atherogenic dyslipidemia. There was, however, little information available in Ethiopia. Therefore, purpose this study was to estimate prevalence dyslipidemia and related Northeast Ethiopian hypertension patients.A systematic random sampling technique used perform a cross-sectional at an institution with 384 chosen participants. A structured questionnaire collect socio-demographic, anthropometric, lifestyle, clinical characteristics...
Background: Thyroid nodules are the most common thyroid disease and its incidence has been rising throughout world. Thus, this study aimed to assess patterns of fine needle aspiration cytology-diagnosed among clinically suspected patients. Methods: A prospective cross-sectional was conducted from April 2021 March 2022 using 424 participants who were referred undergo cytology examination consecutively included. Moreover, two FNAC smears prepared stained Wright Giemsa staining solutions then...
Background: In people living with the human immunodeficiency virus, haematological abnormalities have been linked to an increased risk of disease progression and mortality. Hematological parameters may a positive or negative impact on antiretroviral therapy. The aim this study was assess immuno-haematological HIV-infected patients before after initiation highly active therapy in clinics six health facilities Dessie, Northeast Ethiopia. Methods: A facility-based cross-sectional conducted from...