A5053045947- COVID-19 Clinical Research Studies
- Renal Transplantation Outcomes and Treatments
- SARS-CoV-2 and COVID-19 Research
- Cytomegalovirus and herpesvirus research
- Long-Term Effects of COVID-19
- Organ Transplantation Techniques and Outcomes
- Social Media in Health Education
- COVID-19 Impact on Reproduction
- Herpesvirus Infections and Treatments
- Dialysis and Renal Disease Management
- Extracellular vesicles in disease
- scientometrics and bibliometrics research
- Organ Donation and Transplantation
- Nephrotoxicity and Medicinal Plants
- Transplantation: Methods and Outcomes
- Parvovirus B19 Infection Studies
- Poisoning and overdose treatments
- Polyomavirus and related diseases
- Renal function and acid-base balance
- Vascular Malformations and Hemangiomas
- Parathyroid Disorders and Treatments
- Drug-Induced Hepatotoxicity and Protection
- Pneumocystis jirovecii pneumonia detection and treatment
- Electrolyte and hormonal disorders
- Neonatal Health and Biochemistry
Hospital Universitari Germans Trias i Pujol
2020-2025
Red de Investigación en Sida
2025
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2024
Universitat Autònoma de Barcelona
2020
Bellvitge University Hospital
2013-2019
RELX Group (United States)
2017
Universitat de Barcelona
2014-2015
Institut d'Investigació Biomédica de Bellvitge
2015
Tertiary hyperparathyroidism is a common cause of hypercalcemia after kidney transplant. We designed this 12-month, prospective, multicenter, open–label, randomized study to evaluate whether subtotal parathyroidectomy more effective than cinacalcet for controlling caused by persistent Kidney allograft recipients with and elevated intact parathyroid hormone (iPTH) concentration were eligible if they had received transplant ≥6 months before the an eGFR>30 ml/min per 1.73 m 2 . The primary...
Cytomegalovirus (CMV) infection is still a major complication after kidney transplantation. Although cytotoxic CMV-specific T cells play crucial role controlling CMV survival and replication, current pretransplant risk assessment for only based on donor/recipient (IgG)-serostatus. Here, we evaluated the usefulness of monitoring pre- 6-month cell responses against two dominant antigens (IE-1 pp65) lysate, using an IFN-γ Elispot, predicting advent in cohorts 137 transplant recipients either...
Abstract Background Improving cytomegalovirus (CMV) immune-risk stratification in kidney transplantation is highly needed to establish guided preventive strategies. Methods This prospective, interventional, multicenter clinical trial assessed the value of monitoring pretransplant CMV-specific cell-mediated immunity (CMI) using an interferon-γ release assay predict CMV infection transplantation. One hundred sixty donor/recipient CMV-seropositive (D+/R+) patients, stratified by their baseline...
Abstract Background In kidney transplantation, fibrosis represents the final and irreversible consequence of pathogenic mechanisms that lead to graft failure, in late stages it irremediably precedes loss renal function. The invasiveness biopsy prevents this condition from being frequently monitored, while clinical data are rather unspecific. objective study was find noninvasive biomarkers rejection. Methods We carried out proteomic analysis urinary Extracellular Vesicles (uEVs) a cohort...
Use of immunosuppressive drugs is still unavoidable in kidney-transplanted patients. Since their discovery, calcineurin inhibitors (CNI) have been considered the first-line agents, spite known nephrotoxicity. Chronic CNI toxicity (CNIT) may lead to kidney fibrosis, a threatening scenario for graft survival. However, there controversy regarding CNIT diagnosis, monitoring and therapeutic management, specific effects at molecular level are not fully known. Aiming better characterize patients,...
Interstitial fibrosis and tubular atrophy (IFTA) is a critical factor in the prognosis of kidney health. Currently, IFTA quantitation biopsy samples crucial for diagnosis assessing disease severity, but available non-invasive biomarkers are not satisfactory. Proteomic studies identified urinary vitronectin (VTN) as potential biomarker fibrosis. As mass spectrometry techniques practical use clinical settings, we tested whether evaluation VTN levels through enzyme-linked immunosorbent assay...
Remdesivir is the only antiviral treatment that has been shown to be useful against SARS-CoV-2 infection. It shorts hospitalization time compared placebo. Its effects in Kidney transplant (KT) patients are limited some published cases. We performed a retrospective observational study included all KT admitted between August 01, 2020 and December 31, with pneumonia who received remdesivir. The objective of this was describe experience cohort treated A total 37 developed infection, 7 them rest...
El remdesivir es el único tratamiento antiviral que ha demostrado ser útil frente al SARS-CoV-2 acortando tiempo de hospitalización a placebo. Su efecto en pacientes trasplantados renales (TR) se limita algunos casos publicados. Estudio retrospectivo observacional los TR ingresaron entre 1 agosto 2020 hasta 31 diciembre con neumonía por y recibieron remdesivir. objetivo describir la experiencia una cohorte tratados 37 infección secundaria SARS-CoV-2, 7 ellos resto fueron excluidos CKD-EPI...
Abstract Background and Aims The decrease of immunosuppression (IS) in kidney transplant (KT) recipients with SARS-CoV-2 infection was proposed during the first years pandemic due to lack knowledge course absence vaccines specific treatment. effects this are being assessed a medium-long term. Method Unicentric retrospective study that included 19 patients biopsy after (120 days). We measured acute injury (AKI) de infection, IS rejection episodes renal function evolution 24 months infection....
Abstract Background Kidney transplantations (KT) from uncontrolled donation after cardiac death (uDCD) achieve very good outcomes to short and long follow-up, but the incidence of primary non-function venous thrombosis (VT) is high. The resistance index (RI) kidney transplantation increase in VT cases other diseases. Aims To describe effect prophylactic anticoagulation KT uDCD with RI ≥0.8 avoid its secondary effect. Method Unicentric retrospective cohorts study that included all measured by...
Abstract Background and Aims The treatment of coronavirus disease (COVID-19) is based on the patient’s clinical status levels inflammatory biomarkers. comparative activity these biomarkers in KT patients with COVID-19 pneumonia from severe acute respiratory syndrome 2 (SARS-CoV-2) non-SARS-CoV-2 aetiologies unknown. aim this study was to compare presentation parameters at admission those non-COVID-19 over same period. Method Biomarkers were measured compared between (n=42) (n=18) March...
Abstract Background and Aims Remdesivir is the only treatment that has been shown to be useful against SARS-CoV-2 infection. It shorts hospitalization time compared placebo. Kidney transplant (KT) patients were not included in these studies, therefore, its effects this population limited some published cases. Method We performed a retrospective observational study all KT admitted between August 01, 2020 November 17, with pneumonia who received remdesivir. Patients 200mg loading dose followed...